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Traditional Chinese medicine composition for treating insomnia and application thereof

A kind of composition and technology of traditional Chinese medicine, applied in the field of traditional Chinese medicine composition for treating insomnia

Inactive Publication Date: 2015-12-16
李绍旦 +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Traditional Chinese medicine has unique advantages in the treatment of insomnia, but there are still some problems in the existing traditional Chinese medicine treatment of insomnia, mainly because the therapeutic activity of traditional Chinese medicine needs to be further improved, so as to facilitate the large-scale clinical application of this medicine

Method used

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  • Traditional Chinese medicine composition for treating insomnia and application thereof
  • Traditional Chinese medicine composition for treating insomnia and application thereof
  • Traditional Chinese medicine composition for treating insomnia and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0014] Embodiment 1, Chinese medicine composition of the present invention

[0015] Composition of raw materials of traditional Chinese medicine composition: pinellia 100g, coix seed 200g, Atractylodes macrocephala 150g, calamus shichangpu 150g, rattan vine 150g, bark of albizia juniperus 100g, poria cocos 200g, fried jujube kernel 150g.

Embodiment 2

[0016] Embodiment 2, the preparation method of Chinese medicine composition of the present invention

[0017] The preparation method of Chinese medicine composition preparation:

[0018] (1) According to the formula of the Chinese medicine composition in Example 1, take the raw material of Chinese medicine, soak it in water with 10 times the amount of the material for 1 hour, then decoct and extract 2 times, each time for 1.5 hours, combine the decoction, and concentrate to obtain concentrated Liquid standby;

[0019] (2) Take the concentrated solution obtained in step (1), add ethanol, make the concentration of ethanol in the concentrated solution reach 70%, leave standstill, precipitate, take the supernatant, concentrate to obtain the alcohol precipitation concentrate, and set aside;

[0020] (3) Take the alcohol precipitation concentrate obtained in step (2), add diluent cyclodextrin or cornstarch, mix evenly, granulate, dry, and make granules.

Embodiment 3

[0021] Embodiment 3, the influence of Chinese medicine composition on insomnia rat brain tissue cholecystokinin 8 (CCK8) ring

[0022] 1. Materials and methods

[0023] 1.1 Animal health Thirty male Wistar rats of clean grade, weighing (200±20) g, were provided by Beijing Weitong Lihua Experimental Animal Technology Co., Ltd. (Medical Animal Qualification Certificate SCXK Beijing 2012-0001).

[0024] 1.2 Reagent p-chlorophenylalanine (PCPA) was purchased from Sigma (C6506). CCK-8 radioimmunoassay kit was purchased from Beijing Chinatown Lite Biotechnology Institute.

[0025] 1.3 Traditional Chinese Medicine Hewei Anshen Prescription consists of Pinellia 10g, Raw Coix Seed 20g, Atractylodes Rhizoma Atractylodes Rhizoma 15g, Shichangpu 15g, Caulis Nocturna 15g, Albizia Julibrissin 10g, Poria cocos 20g, Fried Zao Ren 15g, etc. Pharmacy provided and identified. The above-mentioned medicines were decocted according to the traditional decoction method to obtain decoction, con...

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Abstract

The invention relates to a traditional Chinese medicine composition for treating insomnia. The traditional Chinese medicine composition for treating the insomnia is prepared from pinellia ternate, raw coix seeds, white atractylodes rhizomes, grass-leaf sweelflag rhizomes, silk tree albizzia barks, tuber fleeceflower stems, poria cocos and fried jujube kernels. The invention further relates to application of the traditional Chinese medicine composition in preparation of medicines for treating the insomnia. The traditional Chinese medicine composition is superior to western medicines in treating effect and can improve other general symptoms.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating insomnia and its application. Background technique [0002] Insomnia is a clinical manifestation that the human body is not satisfied with sleep time and / or quality and affects social function during the day. Insomnia that excludes the cause of physical disease or mental disorder symptoms and has no clear cause under current medical conditions, and may be caused by individual quality characteristics is called primary insomnia, and it is often referred to as insomnia in clinical practice. Insomnia has a high incidence rate and is very harmful. Occasional insomnia will cause fatigue and uncoordinated movements the next day. Long-term insomnia will cause anxiety, depression, inattention, and memory impairment. It will also affect people's daily life. Life, work, study and social interaction have a serious impact. ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8994A61P25/20
Inventor 李绍旦张印刘毅曹科
Owner 李绍旦
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