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Fructus gardeniae oral liquid capable of protecting liver and benefiting gallbladder and preparation method thereof

A gardenia oral liquid, liver-protecting and gallbladder-protecting technology is applied in food preparation, medical preparations containing active ingredients, pharmaceutical formulations, etc., and can solve problems such as unclear mechanism of action

Inactive Publication Date: 2015-12-23
QINGDAO HENGBO INSTR
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there are few studies on gardenia hepatotoxicity, and its mechanism of action is still unclear, and further research is needed

Method used

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  • Fructus gardeniae oral liquid capable of protecting liver and benefiting gallbladder and preparation method thereof
  • Fructus gardeniae oral liquid capable of protecting liver and benefiting gallbladder and preparation method thereof
  • Fructus gardeniae oral liquid capable of protecting liver and benefiting gallbladder and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

specific Embodiment 1

[0068] Soak the sun-dried gardenia into 10 times the amount of ethanol, heat and extract twice, 1-2 hours each time, remove the supernatant, combine the extract, filter with 100-120 mesh, and then pass through the cut-off molecular weight of 5000-10000 The ultrafiltration column is used for ultrafiltration, and the ultrafiltrate is concentrated under reduced pressure to an extract with a relative density of 1.06 at 80°C, heated and concentrated to a paste, and left to stand for later use to form component 1.

[0069] The rest of the raw materials are Capillaris, Poria, Desmodium, Cyperus, Radix Paeoniae Rubra, Motherwort, Corn Silk, Trichosanthes, Habitat, Polygonum cuspidatum, Anemarrhena, Patrinia, Forsythia, Sanleng, Scutellaria, Polygonatum, Curcuma, Mohan Put lotus and plantain in 10 times the amount of ethanol, soak for 1-2 hours, heat and extract twice, 1-2 hours each time, combine the extracts, let stand, remove the supernatant, and then put them into reduced pressure c...

specific Embodiment 2

[0071] Soak 5000g of dried gardenia into 10 times the amount of ethanol, heat and extract twice, 1-2 hours each time, remove the supernatant, combine the extracts, filter with 100-120 mesh, and then pass through the cut-off molecular weight of 5000- 10000 ultrafiltration column ultrafiltration, the ultrafiltrate is concentrated under reduced pressure to an extract with a relative density of 1.06 at 80°C, heated and concentrated to a paste, and left to stand for later use to form component 1.

[0072] Capillaris 1500g, Poria cocos 1500g, Desmodium 1500g, Cyperus cyperi 1500g, Radix Paeoniae Rubra 1500g, Motherwort 1500g, Corn silk 1500g, Trichosanthes 1500g, Habitat 1500g, Polygonum cuspidatum 1500g, Anemarrhena 1500g, Patrinia 1500g, Forsythia 1500g, three Rib 1500g, Scutellaria baicalensis 1500g, Polygonatum 1500g, Zedoary zedoary 1500g, Eclipta 1500g, Plantain 1500g, put the remaining raw materials into 10 times the amount of ethanol, soak for 1-2 hours, heat and extract 2 ti...

specific Embodiment 3

[0073] Specific embodiment 3: Soak gardenia 4000g that has been aired in water for 1 hour, then put into an extraction tank and heat and boil for 1 hour, filter, and the filtrate is standby; add water to the filter residue, heat for the second time, boil for 45 minutes, filter, and the filtrate is standby; filter residue Add water, heat and boil for the third time for half an hour, filter; put the three filtrates together, filter with gauze, add 50-60% ethanol to the residue, continue leaching for 2 hours at 60°C-70°C, stir once every 10min, filter with gauze , combine the extracts to form component 1. The remaining raw materials are 1200g capillary, Poria 1100g, Desmodium 1100g, Rhizoma Cyperi 1200g, Radix Paeoniae Rubra 1200g, Motherwort 1200g, corn silk 1200g, Trichosanthes 12500g, Habitat 1200g, Polygonum cuspidatum 1200g , Anemarrhena 1200g, Patrinia 1200g, Forsythia 1100g, Trigonum 1100g, Scutellaria baicalensis 1100g, Polygonatum 1200g, Curcuma 1200g, Eclipta 1200g, Plan...

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Abstract

The invention provides fructus gardeniae oral liquid capable of protecting the liver and benefiting the gallbladder. The oral liquid is prepared from, by weight, 10-50 parts of fructus gardeniae, 10-20 parts of herba artemisiae capillariae, 10-20 parts of poria cocos, 10-20 parts of herba lysimachiae, 10-20 parts of rhizoma cyperi, 10-20 parts of radix paeoniae rubra, 10-20 parts of herba leonuri, 10-20 parts of corn stigma, 10-20 parts of radix trichosanthis, 10-20 parts of rehmannia roots, 10-20 parts of rhizoma polygoni cuspidati, 10-20 parts of rhizoma anemarrhenae, 10-20 parts of herba patriniae, 10-20 parts of fructus forsythiae, 10-20 parts of rhizoma sparganii, 10-20 parts of radix scutellariae, 10-20 parts of rhizoma polygonati, 10-20 parts of curcuma zedoary, 10-20 parts of herba ecliptae and 10-20 parts of herba plantaginis. Fructus grdeniae can clear heat, discharge fire and cool the blood. The oral liquid can treat pyreticosis of dysphoria and insomnia, jaundice, gonorrhea, consumptive thirst, hot eyes, pharyngalgia, hematemesis, hemorrhinia, bloody flux, hematuria, heat-toxicity sore and ulcer and sprain swelling.

Description

technical field [0001] The invention relates to medical health products containing raw materials derived from plants, animals or minerals, in particular to a gardenia oral liquid for protecting the liver and promoting gallbladder and a preparation method thereof. Background technique [0002] Hepatobiliary disease is a common and frequently-occurring disease that seriously endangers human health. At present, there is no specific drug to promote liver cell regeneration and prevent liver cell necrosis. Gardenia jasminoides Ellis is the dry and mature fruit of Gardenia jasminoides Ellis, a plant of the Rubiaceae family, which belongs to the dual-use medicinal and edible items announced by the Ministry of Health. Gardenia is bitter in taste and cold in nature. It has the effects of purging fire and relieving restlessness, clearing heat and dampness, cooling blood and detoxifying, and is a commonly used clinical medicine for protecting the liver and gallbladder. Gardenia is used...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61K9/08A61P1/16A23L1/29
Inventor 赵玉妹
Owner QINGDAO HENGBO INSTR
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