46 results about "Hepatobiliary disease" patented technology

The invention discloses a sulfated bile acid (SBA) enzyme fluorescence capillary analysis and an SBA fluorescence quantitative test kit (SBA-FCA-Kit), which belongs to the field of a clinic biochemistry inspection field and is suitable for the fast screening and diagnosing of liver and gall diseases, more particularly, is suitable for the early period discovery of jaundice in neonatal period and congenital biliary atresia. After being mixed with fluorescence reaction liquid, a biology sample is sucked by an SBA capillary biology reactor (SBA-CBR) which contains sulfated bile acid sulfoacid esterase and Beta-hydroxysteroid dehydrogenase to determine the blank fluorescence intensity of the SBA-CBR under a given excitation wavelength and an emission wavelength; then the biology sample is ledto continuously react for a certain time and the fluorescence intensity is determined; the amount of the SBA in the sample is determined by using fluorescence intensity difference value. The SBA-FCA-Kit is composed of an SBA-CBR and fluorescence reaction liquid containing Beta-NAD<+>, an electric transmission body and diazoresorcinal, etc.

The invention discloses a traditional Chinese medicine composition for preventing and treating hepatobiliary diseases. The composition is prepared from fructus citri sarcodactylis, flos chrysanthemi,fructus lycii, radix puerariae, fructus mori, fructus citri, flos rosae rugosae, poria cocos, fructus crataegi, semen cassiae, herba taraxacum, rhizoma phragmitis, isodon amethystoides or serrate rabdosia herb. The traditional Chinese medicine composition has the advantages that through the synergistic effect of the fructus citri sarcodactylis, flos chrysanthemi, fructus lycii, radix puerariae, fructus mori, fructus citri, flos rosae rugosae, poria cocos, fructus crataegi, semen cassiae, herba taraxacum, rhizoma phragmitis, isodon amethystoides or serrate rabdosia herb, both the symptoms and root causes of hepatobiliary diseases are systematically solved; the root causes of the hepatobiliary diseases are eliminated by clearing heat, removing toxicity, dispelling wind, removing heat, nourishing yin, moistening dryness, removing heat from the liver, astringing the liver, activating blood and dissipating blood stasis; cough is relieved and the body is not harmed through diuretic therapy and defaecation; the symptoms of the hepatobiliary diseases are treated by soothing the liver, harmonizing stomach, nourishing the liver and kidney, tonifying the spleen, clearing damp, reinforcing qiand nourishing blood; the related viscera of the hepatobiliary system can cooperatively work in harmony to form a virtuous cycle with a viscera function to prevent relapse.

A Chinese medicine for treating hepatobiliary diseases, such as acute or chronic cholecystitis, biliary tract infection and cholelithiasis, is prepared from 8 raw materials including artificial bezoar, silymarinum, rhubarb, dandelion herb, etc. Its preparing process is also disclosed.

The invention discloses an extract of bupleurum and preparation method thereof, belonging to the field of traditional Chinese medicine. The preparation method is as follows: drying and grinding the stem and / or leaves of the bupleurum to obtain coarse powder of the bupleurum; adding 75-95% of alcohol solution with 8-10 times of weight for reflux extraction at the temperature of 75-85 DEG C for 1-3times, carrying out extraction for 2-4h every time, combining extracting solution and filtering the extracting solution, recycling and concentrating ethanol until the relative density is 1.0-1.1; adding water with 8-10 times of volume into concentrated solution, placing the mixture for 12h and filtering the mixture, eluting the mixture with D101 macroporous resin column, collecting eluate and vacuum-drying the eluate at the temperature of 70 DEG C to obtain the extract powder of the bupleurum. The invention also discloses a pharmaceutical composition containing the extract of the bupleurum andapplication thereof in preparing drugs for treating liver and nerve diseases.

This disclosure relates to oligonucleotides, compositions and methods useful for reducing CYP27A1 expression, particularly in hepatocytes. Disclosed oligonucleotides for the reduction of CYP27A1 expression may be double-stranded or single-stranded and may be modified for improved characteristics such as stronger resistance to nucleases and lower immunogenicity. Disclosed oligonucleotides for the reduction of CYP27A1 expression may also include targeting ligands to target a particular cell or organ, such as the hepatocytes of the liver, and may be used to treat hepatobiliary disease and related conditions (e.g., liver fibrosis).

The present invention relates to a high-immune anti-stress freshwater fish mixed feed, comprising a base material. The base material includes fish meal, bean pulp, wheat, cottonseed meal, rapeseed meal, wheat middling, rice bran and soybean oil; and also includes the following substances by weight: 1.6-2.5% of calcium phosphate salt, 1.6-2.5% of bentonite, 1.6-2.5% of zeolite powder, 0.15-0.22% of choline chloride, 0.10-0.25% of salt, 0.03-0.1% of composite probiotics, 0.08-0.2% of vitamin C, 0.06-0.2% of composite hepatobiliary agent, 0.04-0.15% of composite immunostimulant, 0.5-2% of composite vitamin and 2% of composite mineral salt. By using the feed, the survival rate, feed efficiency and anti-stress ability of common freshwater fishes can be improved, the incidences of hepatobiliary diseases and water eutrophication are reduced, therefore the ordinary freshwater fish farming costs are reduced, and aquatic product quality and yield and economic benefit per unit are improved.

The invention discloses a traditional Chinese medicine for treating hepatobiliary diseases of turtles. The traditional Chinese medicine comprises plantain seed, tulip, orange shell, common burreed rhizome, danshen root, peach seed, ground beetle and oriental waterplantain rhizome which have the effect of clearing heat and detoxicating and diminishing inflammation, and Indian buead and zedoary which have the effect of sterilizing, wherein the tulip serves as a main medicament; and the orange shell, the Indian buead, the common burreed rhizome, the danshen root, the peach seed, the ground beetle, the oriental waterplantain rhizome and the plantain seed serve as adjuvant. The raw materials are easy to purchase and process; the using method of the traditional Chinese medicine is simple; the effect on treating hepatobiliary diseases of turtles is good; and the traditional Chinese medicine has no toxic or side effects after being taken by the turtles, does not affect the water body growing environment of turtles, can be stored for a long time and is convenient to preserve.

The invention provides a medicinal preparation for treating hepatobiliary diseases and a preparation method thereof. The medicinal preparation comprises ascariasis, hydroxypropyl cellulose, starch, magnesium stearate, HS-15 and an ethanol solution for preparing a soft material. The dissolution curves of an ascariasis tablet provided by the invention in four mediums are consistent with those of anoriginal product, thereby ensuring the same efficacy as the original product.

The invention relates to a pharmaceutical composition for preventing and treating liver and gallbladder disease of aquatic animals. The components of the pharmaceutical composition and their weight percentages are: 1-15% of diisopropylamine dichloroacetate; 1-15% of poria cocos; 1-15% of astragalus; Atractylodes macrocephala 1-15%; Radix Radix Isatidis 1-15%; Semen psyllium 1-15%; For accessories. The present invention adds western medicine ingredients into the traditional Chinese medicine, which has a short onset time, can effectively antibacterial, enhance immunity, protect the liver and promote gallbladder, and is a pharmaceutical composition for preventing and treating liver and gallbladder diseases in aquatic animals that can effectively improve immunity and Its preparation method and application.