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Traditional Chinese medicine extract composition for preparing medicine for resisting skin fungal infection

A skin fungus and composition technology, applied in the field of traditional Chinese medicine extract composition, can solve the problems of high recurrence rate and low cure rate, and achieve the effect of strengthening antifungal effect, improving curative effect, and good safety

Active Publication Date: 2016-03-02
THE SECOND HOSPITAL OF HEBEI MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the first-choice drugs for the treatment of dermatophytes are chemically synthesized western medicine external preparations and compound preparations, such as dacryline, clotrimazole, terbinafine, ketoconazole, and compound preparations such as pevisone, trimexin, and triamcinolone acetonide Most bacteriostatic agents have certain antifungal effects and can relieve symptoms, but the cure rate is low and the recurrence rate is high

Method used

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  • Traditional Chinese medicine extract composition for preparing medicine for resisting skin fungal infection
  • Traditional Chinese medicine extract composition for preparing medicine for resisting skin fungal infection

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] Embodiment 1 oily ointment

[0023] Cinnamaldehyde: 4.0g (40 parts by weight)

[0024] Eugenol: 2.0g (20 parts by weight)

[0025] Laurazone: 1.0g (10 parts by weight)

[0026] Tween: 3.0g (30 servings)

[0027] The cinnamaldehyde, eugenol and laurocapram are dissolved in Tween to form a drug component solution, which is then gradually added to the water-in-oil matrix and stirred evenly to obtain an oily ointment.

Embodiment 2

[0028] Embodiment 2 emulsion type ointment

[0029] Cinnamaldehyde: 2.5g (50 parts by weight)

[0030] Eugenol: 1.25g (25 parts by weight)

[0031] Laurazone: 1.0g (20 parts by weight)

[0032] Tween: 4.0g (50 parts by weight)

[0033] The cinnamaldehyde, eugenol and laurocapram are dissolved in Tween to form a drug component solution, and then gradually added to the oil-in-water base, and stirred evenly to obtain an oil-in-water emulsion type ointment.

Embodiment 3

[0034] Embodiment 3 liniment

[0035] Cinnamaldehyde: 3.0g (60 parts by weight)

[0036] Eugenol: 2.0g (40 parts by weight)

[0037] Laurazone: 1.5g (30 parts by weight)

[0038] Tween: 8g (80 parts by weight)

[0039] Dissolving cinnamaldehyde, eugenol and azone with Tween to form a drug component solution; will step The Chinese medicine component solution can be added to 50-75% ethanol.

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Abstract

The invention discloses a traditional Chinese medicine extract composition for preparing a medicine for resisting skin fungal infection and relates to a traditional Chinese medicine extract composition. The traditional Chinese medicine extract composition consists of the following raw material components in parts by weight: 40-60 parts of cinnamaldehyde, 20-40 parts of eugenol and 10-30 parts of laurocapm; preferably the traditional Chinese medicine extract composition further consists of 30-80 parts by weight of Tween-80; preferably, the traditional Chinese medicine extract composition disclosed by the invention consists of the following raw material components in parts by weight: 45-55 parts of cinnamaldehyde, 25-35 parts of eugenol and 15-25 parts of laurocapm; and the fungus is superficial fungus. The invention provides a traditional Chinese medicine extract composition for preparing the medicine for resisting skin fungal infection, and the traditional Chinese medicine extract composition is natural in raw material, significant in action and curative effect on dermatomycoses, such as tinea corporis, tinea cruris, tinea versicolor, vaginitis and the like, caused by various skin ringworms, low in toxic and side effects and not easy for causing drug resistance, and active ingredients of the medicine can rapidly penetrate into skin.

Description

technical field [0001] The invention belongs to a traditional Chinese medicine extracting composition, in particular to a traditional Chinese medicine extracting composition for preparing anti-fungal skin infection medicine. Background technique [0002] Dermatomycosis is a variety of dermatophytosis caused by superficial fungal infection, such as tinea corporis, jock itch, tinea versicolor, tinea manuum, tinea capitis, and vaginitis. Superficial fungi include Trichophyton rubrum, plaster-like hair Ringworm, Trichophyton flocculus, Microsporum gypsum, Microsporum canis, Pityrosporum, Candida, etc. At present, the first-choice drugs for the treatment of dermatophytes are chemically synthesized western medicine external preparations and compound preparations, such as dacryline, clotrimazole, terbinafine, ketoconazole, and compound preparations such as perisone, trimexin, and triamcinolone acetonide Most bacteriostatic agents have certain antifungal effects and can relieve sym...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/11A61K47/22A61P17/00A61P31/10A61K31/085
Inventor 王刚生邓洁华
Owner THE SECOND HOSPITAL OF HEBEI MEDICAL UNIV
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