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Traditional Chinese medicine composition with anti-depression function and preparation method thereof

An antidepressant and composition technology, which is applied in the field of traditional Chinese medicine compositions with antidepressant effects and the preparation thereof, can solve the problems of inconvenient quality control, low dosage of medicines, and many ineffective components.

Inactive Publication Date: 2016-03-09
TIANJIN UNIV OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The method of the present invention overcomes the defects of the traditional preparation of the Jiaotai Pill compound, such as large dosage, simple processing, inconvenient quality control, and many ineffective components; the prepared composition has significant curative effect, enhanced drug absorption, high bioavailability, and less dosage for patients , while achieving the effect of depression treatment and delaying the disease process, it also provides ideas and methods of health care prevention

Method used

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  • Traditional Chinese medicine composition with anti-depression function and preparation method thereof
  • Traditional Chinese medicine composition with anti-depression function and preparation method thereof
  • Traditional Chinese medicine composition with anti-depression function and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0062] 1. Prepare raw materials according to the following weight ratio (g)

[0063] Coptidis 200

[0064] Cinnamon 20

[0065] Wherein, Coptidis Rhizoma and Cinnamon are pulverized respectively, and are passed through a 20-mesh sieve respectively, and set aside;

[0066] 2. Preparation of Coptis chinensis liquid

[0067] 2A) Put 200g of crushed and sieved Coptis chinensis powder in a round-bottomed flask (5L), install the round-bottomed flask on a heating mantle, add water, assemble a condenser above the round-bottomed flask, heat, and carry out Coptis chinensis. Reflux extraction for the first time, wherein the ratio of the weight of water added to the weight (dry weight) of Coptidis Rhizoma is 10:1; filter after reflux extraction for 170min, obtain Coptidis Rhizoma extract for the first time;

[0068] 2B) Adding water to the filter residue, the ratio of the weight of water to the weight (dry weight) of Coptidis Rhizoma is 8:1, heating, performing the second reflux extrac...

Embodiment 2

[0082] 1. Prepare raw materials according to the following weight ratio (g)

[0083] Coptidis 200

[0084] cinnamon 10

[0085] Wherein, Coptidis Rhizoma and Cinnamon are pulverized respectively, and are passed through a 20-mesh sieve respectively, and set aside;

[0086] 2. Preparation of Coptis chinensis liquid

[0087] 2A) Put 200g of crushed and sieved Coptis chinensis powder in a round-bottomed flask (5L), install the round-bottomed flask on a heating mantle, add water, assemble a condenser above the round-bottomed flask, heat, and carry out Coptis chinensis. Reflux extraction for the first time, wherein the ratio of the weight of water added to the weight (dry weight) of Coptidis Rhizoma is 12:1; filter after 200min of reflux extraction, obtain Coptidis Rhizoma extract for the first time;

[0088] 2B) Add water to the filter residue, the ratio of the weight of water to the weight of Coptidis rhizome (dry weight) is 10:1, heat, perform the second reflux extraction of C...

Embodiment 3

[0099] 1. Prepare raw materials according to the following weight ratio (g)

[0100] Coptidis 200

[0101] Cinnamon 40

[0102] Wherein, Coptidis Rhizoma and Cinnamon are pulverized respectively, and are passed through a 20-mesh sieve respectively, and set aside;

[0103] 2. Preparation of Coptis chinensis liquid

[0104] 2A) Put 200g of crushed and sieved Coptis chinensis powder in a round-bottomed flask (5L), install the round-bottomed flask on a heating mantle, add water, assemble a condenser above the round-bottomed flask, heat, and carry out Coptis chinensis. Reflux extraction for the first time, wherein the ratio of the weight of water added to the weight (dry weight) of Coptidis Rhizome is 8:1; filter after reflux extraction for 150min, obtain Coptidis Rhizoma extract for the first time;

[0105] 2B) Add water to the filter residue, the ratio of the weight of water to the weight (dry weight) of Coptidis Rhizoma is 6:1, heat, perform the second reflux extraction of Co...

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Abstract

The invention discloses a traditional Chinese medicine composition with an anti-depression function and a preparation method of the traditional Chinese medicine composition. The preparation method comprises the steps of firstly, carrying out heating reflux extraction after respectively and uniformly mixing coptis chinensis and cinnamomum cassia with water, and obtaining coptis chinensis liquor and cinnamomum cassia liquor; distilling by water vapor to obtain cinnamomum cassia volatile oil; then sequentially carrying out concentration treatment and drying treatment after uniformly mixing the coptis chinensis liquor, the cinnamomum cassia liquor and the cinnamomum cassia volatile oil. Compared with Jiaotai pills prepared through a traditional decoction method, the traditional Chinese medicine composition with the anti-depression function, disclosed by the invention, has the advantages that chemical components are relatively clear and definite, the curative effect is remarkable, the quality is controllable, and the like; the traditional Chinese medicine composition with the anti-depression function, prepared by the preparation method has the characteristics that the pharmacological effect is clear, the effect is achieved rapidly, toxic and side effects are little, the preparation technology is simple, the operation and the popularization are convenient, and a new medicine source is provided for preventing and treating depression and complications thereof, obstacles or symptoms.

Description

technical field [0001] The invention relates to a medicine or health food for preventing, alleviating and / or treating neurological diseases of affective disorder and its preparation method, in particular to a traditional Chinese medicine composition with antidepressant effect and its preparation method, belonging to the technical field of traditional Chinese medicine . Background technique [0002] Major depressive disorder is the main type of mood disorders. It is a common mental disease with high prevalence, high burden, high suicide, easy relapse, and easy disability. It is characterized by obvious and persistent low mood. The main manifestations may be accompanied by corresponding changes in thinking and behavior. [0003] The main clinical manifestations of depression are depressed mood, loss of interest, self-blame, decreased self-evaluation, and fatigue, etc., and there may be neuromotor hysteresis or agitation, often accompanied by symptoms such as decreased appetit...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/718A61P25/24
Inventor 于春泉高杉李琳高树明张敏李苒
Owner TIANJIN UNIV OF TRADITIONAL CHINESE MEDICINE
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