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Traditional Chinese medicine composition capable of enhancing memory and improving depression, its preparation method and application

A memory-enhancing and composition-enhancing technology, applied in drug combinations, medical preparations containing active ingredients, and pharmaceutical formulas, can solve problems such as cardiotoxicity, side effects, and breast cancer, and achieve convenience in clinical use and improvement of pathology link, the effect of repairing the cholinergic nervous system

Active Publication Date: 2019-07-16
NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the side effects of these drugs are often criticized. In addition to common indigestion such as dizziness, nausea and vomiting, they often cause insomnia and other sleep disorders.
At the same time, selegiline is also cardiotoxic
Estrogen replacement therapy also carries breast cancer risk

Method used

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  • Traditional Chinese medicine composition capable of enhancing memory and improving depression, its preparation method and application
  • Traditional Chinese medicine composition capable of enhancing memory and improving depression, its preparation method and application
  • Traditional Chinese medicine composition capable of enhancing memory and improving depression, its preparation method and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] A kind of embodiment 1 has enhanced memory, the preparation method of the Chinese medicine composition of improving depressive mood effect, comprises the steps:

[0030] (1) Take 1 part of ginseng, 1 part of Polygala, 1 part of Shichangpu, 1 part of Poria cocos, 2 parts of Ophiopogon japonicus, 1 part of Schisandra chinensis, 0.5 part of turmeric, and 0.5 part of gardenia, and mix them. Add 60% ethanol in an amount 8 times the weight of the medicinal material, reflux for extraction for 120 min, filter, and collect the filtrate and filter residue.

[0031] (2) Take the medicinal dregs in the step (1), add 60% ethanol in a volume 10 times the weight of the medicinal material, extract under reflux for 120 min, filter, and collect the filtrate.

[0032] (3) Combine the filtrate obtained in step (1) and step (2), concentrate under reduced pressure to obtain extract, add 0.1 part of Ginkgo biloba extract, and obtain the extract at low temperature and under reduced pressure. ...

Embodiment 2

[0033] A kind of embodiment 2 has enhanced memory, the preparation method of the Chinese medicine composition of improving depression effect, comprises the steps:

[0034] (1) Take 5 parts of ginseng, 3 parts of Polygala, 5 parts of Shichangpu, 8 parts of Poria cocos, 5 parts of Ophiopogon japonicus, 5 parts of Schisandra chinensis, 2 parts of turmeric, and 2 parts of gardenia, and mix them. Add 60% ethanol in an amount 8 times the weight of the medicinal material, reflux for extraction for 120 min, filter, and collect the filtrate and filter residue.

[0035] (2) Take the medicinal dregs in the step (1), add 60% ethanol in a volume 10 times the weight of the medicinal material, extract under reflux for 120 min, filter, and collect the filtrate.

[0036] (3) Combine the filtrate obtained in step (1) and step (2), concentrate under reduced pressure to obtain extract, add 0.5 part of Ginkgo biloba extract, and obtain the extract at low temperature and under reduced pressure.

Embodiment 3

[0037] Embodiment 3 A kind of preparation method that has enhanced memory, improves the Chinese medicine composition of depressed mood effect, comprises the steps:

[0038] (1) Take 3 parts of ginseng, 2 parts of Polygala, 2 parts of Shichangpu, 3 parts of Poria cocos, 3 parts of Ophiopogon japonicus, 2 parts of Schisandra chinensis, 1 part of turmeric, and 2 parts of gardenia, and mix them. Add 60% ethanol in an amount 8 times the weight of the medicinal material, reflux for extraction for 120 min, filter, and collect the filtrate and filter residue.

[0039] (2) Take the medicinal dregs in the step (1), add 60% ethanol in a volume 10 times the weight of the medicinal material, extract under reflux for 120 min, filter, and collect the filtrate.

[0040] (3) Combine the filtrate obtained in step (1) and step (2), concentrate under reduced pressure to obtain extract, add 0.1 part of Ginkgo biloba extract, and obtain the extract at low temperature and under reduced pressure.

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Abstract

The invention discloses a traditional Chinese medicine composition capable of enhancing memory and relieving depression, a preparation method and applications thereof. The composition is composed of the following raw materials in parts by weight: 2 to 5 parts of ginseng, 1 to 5 parts of polygala root, 1 to 5 parts of acorus tatarinowii, 2 to 5 parts of poria cocos, 1 to 5 parts of dwarf lilyturf tuber, 1 to 5 parts of Chinese magnoliavine, 1 to 5 parts of curcuma tuber, 1 to 5 parts of cape jasmine, and 0.1 to 0.5 part of ginkgo leaf extract. The provided traditional Chinese medicine composition can prevent neurodegeneration dementia, relieve suppression, delay the deterioration of memory, and improve the memory of patients of neurodegeneration dementia, has the advantages of reliable curative effect, good safety, and low happening rate of adverse reaction, and can be used to prepare drugs for preventing neurodegeneration dementia and suppression.

Description

technical field [0001] The invention relates to a natural product composition, in particular to a traditional Chinese medicine composition capable of enhancing memory and improving depression and a preparation method thereof. Background technique [0002] Various sources show that China has entered an aging society and is developing at an accelerated pace. China's existing elderly population has exceeded 160 million, and the number is increasing at a rate of nearly 8 million every year. It is estimated that by 2050, China's elderly population will reach one-third of the total population. With the rapid increase of the elderly population, especially the average annual growth rate of 1 million elderly people over 80 years old and the disabled elderly, the demand for life care, rehabilitation care, medical care, spiritual culture, etc. of the elderly has become increasingly prominent, and the problem of providing for the aged has become increasingly severe . [0003] Among a...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9066A61P25/28A61P25/24
CPCA61K36/076A61K36/16A61K36/258A61K36/57A61K36/69A61K36/744A61K36/79A61K36/888A61K36/8968A61K36/9066A61K2236/333A61K2236/39A61K2300/00
Inventor 朱悦段金廒詹华强钱大玮
Owner NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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