100results about How to "No obvious side effects were found" patented technology

The invention discloses a process of preparing Dehydroandrographolide Succinate Sodium and Potassium salts with Potassium Dehydroandrograpolide Succinate. The process comprises the steps of: weighing right amount of Potassium Dehydroandrograpolide Succinate, adding absolute ethyl alcohol about 3 to 6 times to make suspension; weighting mole Sodium bicarbonate in equal weight, adding water to dissolve, dripping slowly Sodium bicarbonate solution in potassium dehydroandrograpolide succinate suspension in a water bath at a temperature of between 40 and 60 DEG C, mixing into liquid medicine and defecating, dissolving impurity and filtering, putting on a 0.22 mu m filter membrane, adding absolute ethyl alcohol about 7 to 12 times while mixing, after 10 to 30 minutes of mixing, natural crystallization seeds out after 13 to 18 hours standing in room temperature; filtering and washing 2 to 3 times with right amount of absolute ethyl alcohol; filtering and drying with less pressure. The invention provides a process route of preparing potassium sodium dehydroandroan drographolide succinate for injection with high purity, which is high in process yields, high in product purity, good in solubility, less in impurity and complete in combination of Potassium and Sodium; no obvious toxic and side effect in clinic application, the preparation is more stable compared with the similar and can be prepared into various preparations.

The present invention relates to one kind of sodium-potassium andrographolide-semisuccinate and its preparations. On the basis of potassium andrographolide-semisuccinate, which is not enough stable and is likely to produce precipitate and negative effect, sodium-potassium andrographolide-semisuccinate is developed and has relatively high stability and less side effect. The sodium-potassium andrographolide-semisuccinate is prepared into injection, powder for injection and other forms.

The invention discloses a prepared traditional Chinese medicinal preparation for treating diabetes which is prepared from the following Chinese herbs, astragalus root, honey-suckle stem, oriental water plantain rhizome, Chinese angelica root, root of red rooted saliva, mulberry, Chinese honey locust and dahurian angelica root.

The invention relates to a traditional Chinese medicine composition for treating gastrointestinal disease and a preparation method thereof. The traditional Chinese medicine composition is prepared from elecampane, agilawood, fructus aurantii, sandalwood, rheum officinale, mangnolia officinalis, Muscat and defatted croton seed powder mixed with other medicaments. The invention is mainly used for treating diseases such as acute diarrhea, irritable bowel syndrome and the like in clinic.

The invention discloses a fleece-flower root-containing traditional Chinese medicine preparation and a preparation method thereof. The fleece-flower root-containing traditional Chinese medicine preparation comprises, by mass, 50-100 parts of fleece-flower root, 15-25 parts of cassia seed, 20-30 parts of poria cocos, 25-50 parts of Chinese angelica, 60-80 parts of eucommia, 50- 80 parts of rhizoma rehmanniae, 25-35 parts of ligusticum wallichii, 60-80 parts of mannitol and 1-2 parts of talcum powder. The fleece-flower root-containing traditional Chinese medicine preparation adopts fleece-flower root as a raw material, contains stibene glucoside as a main component, can be used for adjunctive treatment on dementia, apoplexy, coronary heart disease and angina pectoris, can be used for daily health care, can improve human immunity, can prevent eqpidemic diseases, can delay aging and can reduce fat. Through utilization of the natural plants, the fleece-flower root-containing traditional Chinese medicine preparation has no obvious toxic or side effect and high safety, can be absorbed easily, can produce effects fast, is convenient for use, can remove toxins, can eliminate carbuncle and can moisten the intestines to relax the bowels. The fleece-flower root-containing traditional Chinese medicine preparation can mainly treat scrofula and carbuncle, rubella pruritus and constipation due to intestinal dryness. Prepared fleece-flower root has effects of nourishing liver and kidney, boosting essence and blood, blacking beard and hair, strengthening muscles and bones, resisting oxidation, resisting aging, improving cognitive ability, improving immunity, reducing blood fat and resisting atherosclerosis. The preparation method has a low cost and simple processes and can be widely used.

The invention relates to a gastrointestinal disease-treating traditional Chinese medicine composition containing Chinese eaglewood and a preparation method thereof. The traditional Chinese medicine composition is prepared with costustoot, Chinese eaglewood, immature bitter orange, sandalwood, golden thread or baical skullcap root, officinal magnolia bark or swordlike atractylodes rhizome, musk, defatted croton seed powder, Chinese date, Szechuan lovage rhizome and the like. Clinically, the traditional Chinese medicine composition mainly treats diseases such as acute diarrhea and irritable bowel syndrome.

The present invention discloses a medicine for curing cancers. It is characterized by that it is an injection preparation prepared by extracting effective components of the Chinese medicinal materials of rabdosia rubescens, gentian root, rhinoceros horn, black nightshade, bushy sophora root, epimedium and walnut twigs. Said invented medicine mainly can be used for curing carcinoma of esophagus, carcinoma of stomach, hepatis carcinoma, oral carcinoma and cervical carcinoma, and its effective rate can be up to above 95%.

The invention discloses a traditional Chinese medicine composition capable of enhancing memory and relieving depression, a preparation method and applications thereof. The composition is composed of the following raw materials in parts by weight: 2 to 5 parts of ginseng, 1 to 5 parts of polygala root, 1 to 5 parts of acorus tatarinowii, 2 to 5 parts of poria cocos, 1 to 5 parts of dwarf lilyturf tuber, 1 to 5 parts of Chinese magnoliavine, 1 to 5 parts of curcuma tuber, 1 to 5 parts of cape jasmine, and 0.1 to 0.5 part of ginkgo leaf extract. The provided traditional Chinese medicine composition can prevent neurodegeneration dementia, relieve suppression, delay the deterioration of memory, and improve the memory of patients of neurodegeneration dementia, has the advantages of reliable curative effect, good safety, and low happening rate of adverse reaction, and can be used to prepare drugs for preventing neurodegeneration dementia and suppression.

The invention relates to a Chinese medicinal composition for treating gastrointestinal disease and a preparation method thereof. The composition is prepared from costustoot, Chinese eaglewood, bitter orange, sandalwood, rhubarb, officinal magnolia bark, musk and defatted croton seed powder in a basic prescription and other medicines, and is mainly used for treating diseases such as acute diarrhea, irritable bowel syndrome and the like clinically.

The invention relates to a sandalwood-containing traditional Chinese medicine for treating gastrointestinal diseases and a preparation method thereof. The traditional Chinese medicine is prepared by processing ten drugs such as costustoot, sandalwood, immature bitter orange, fructus amomi, rhizoma coptidis or radix scutellariae, mangnolia officinalis or rhizoma atractylodis, muskiness, defatted croton seed powder, Chinese date and ligusticum wallichii and the like, is mainly used for treating diseases such as acute diarrhea, irritable bowel syndrome and the like on clinic.

The invention discloses a traditional Chinese medicine for treating the constipation, and a preparation method and an application thereof. The traditional Chinese medicine is prepared by using the following raw medicines, by mass, 25-35 parts of Radix aconiti lateralis preparata, 5-15 parts of cinnamon, 15-25 parts of epimeddium, 10-20 parts of cortex magnoliae officinalis, 15-25 parts of Longstamen Onion Bulb, 25-35 parts of Radix Puerariae and 15-25 parts of Poria cocos. The preparation method comprises the following steps: extracting volatile oil from the cinnamon, carrying out clathration by beta-cyclodextrin to obtain a clathrate, and refluxing other traditional Chinese medicines by ethanol to prepare a preparation. The traditional Chinese medicine can be used for treating the constipation, especially spleen and kidney yang deficiency type constipation; researches show that the traditional Chinese medicine adopting natural plants has no obvious toxic side effects and has high security; and the traditional Chinese medicine can be processed to prepare a pharmaceutical tablet, capsule or granule to be widely used.

The invention relates to a traditional Chinese medicine composition for treating gastrointestinal disease and a preparation method thereof. The traditional Chinese medicine composition is prepared from elecampane, pericarpium citri reticulatae viride or rhizoma cyperi, fructus aurantii, sandalwood, rheum officinale, mangnolia officinalis, muscat, defatted croton seed powder, fructus Zizyphi and ligusticum wallichii. The invention is mainly used for treating diseases such as acute diarrhea, irritable bowel syndrome and the like in clinic.

The invention discloses a traditional Chinese medicine for treating constipation and a preparation method and an application of the traditional Chinese medicine. The traditional Chinese medicine is prepared from raw materials in parts by weight as follows: 25-35 parts of largehead atractylodes rhizomes, 7-17 parts of astragalus membranaceus, 5-15 parts of desertliving cistanche, 5-15 parts of hemp fruits, 5-15 parts of bitter orange, 2-12 parts of medicated leaven and 1-8 parts of cassia bark. Volatile oil is extracted from the largehead atractylodes rhizomes, the bitter orange and the cassia bark and included by beta-cyclodextrin, and an inclusion compound is obtained; the desertliving cistanche and the medicated leaven are decocted in water, other Chinese herbal medicines are subjected to alcohol reflux, a preparation is prepared and has the efficacy of treating constipation, especially spleen deficiency and qi weakness type constipation; natural plants are adopted, no remarkable toxic or side effects are found in researches, the safety is high, and the traditional Chinese medicine can be made in the form of tablets, capsules or granules in pharmacy and can be widely used.

The invention relates to a traditional Chinese medicine composition for treating gastrointestinal diseases and a preparation method thereof. The traditional Chinese medicine composition is prepared from tens of traditional Chinese herbs of costustoot, agilawood, fructus aurantii, sanders, rheum officinale, mangnolia officinalis, muak, defatted croton seed powder, date and ligusticum wallichii. The traditional Chinese medicine composition is mainly used for treating diseases of acute diarrhea, irritable bowel syndrome and the like in clinic.

The invention relates to a costunolide-containing traditional Chinese medicine composition for treating gastrointestinal diseases and a preparation method thereof. The traditional Chinese medicine composition is prepared from basic medicines and other medicines, wherein, the basic medicines comprise the following components: costunolide, naringin, santalol, chrysophanol, artificial musk, ligustrazine, croton oil and polysaccharides from Chinese red dates. The traditional Chinese medicine composition is mainly used for clinically treating diseases such as acute diarrhea, irritable bowel syndrome and the like.

The invention discloses an application of B-ecdysterone in making medicine for curing and / or preventing osteoporosis. The invention respectively studies the protective action of B-ecdysterone on bone metabolism at both general level and cellular level. When cultured together with osteoblast strain MC3T3-E1 and primary mice marrow stromal stem cell, B-ecdysterone can obviously promote the osteogenic differentiation of both cells. A mice osteoporosis model is established through tretinoin lavage, and the in vivo activity experiment of B-ecdysterone is carried out through adopting an intraperitoneal injection method and a lavage method; the results show that B-ecdysterone has the functions of increasing bone density, the content of mineral matters in bone tissues and thighbone diameter and improving hydroxyproline enzymatic activity. Therefore, B-ecdysterone can be used to make medicine for curing and / or preventing osteoporosis as well as medicine for promoting osteogenic differentiation and bone healing.

A Chinese medicine in the form of pill for treating hypertension and resolving phlegm is prepared from 14 Chinese-medicinal materials including borneol, mint, pearl, white peony root, etc. Its preparing process is also disclosed.

The invention discloses a traditional Chinese medicine preparation for treating periodontitis. The traditional Chinese medicine preparation for treating periodontitis is composed of the following medicinal raw materials: 3-8g of astragalus membranaceus, 3-8g of asarum, 3-8g of cinnabar, 3-8g of borneol, 2-4g of borax, 1.5-2.5g of realgar, 2-4g of radices trichosanthis, 1.5-2.5g of camphor, 2-4g of alumen, 1.5-2.5g of indigo naturalis and 30-60g of aloe. A preparation method comprises the following steps of: preparing astragalus membranaceus, asarum, cinnabar, borneol, borax, realgar, radices trichosanthis, camphor, alumen and indigo naturalis, mixing and uniformly grinding, then adding aloe, uniformly grinding, and blending into paste, namely the traditional Chinese medicine preparation. During treatment, the traditional Chinese medicine preparation for treating periodontitis is injected to the part with periodontitis by an injector or applied to the surface of the part with periodontitis by a cotton swab, applied once a day, one week for a treatment course, and periodontitis can be generally cured within 2-3 treatment courses. The traditional Chinese medicine preparation for treating periodontitis disclosed by the invention is capable of rapidly reducing the surface with periodontitis, reducing periodontitis exudation, relieving pain symptom and obviously reducing disease course, and free of obvious toxic and side effects.

The invention relates to a gastrointestinal disease-treating traditional Chinese medicine composition containing costustoot and a preparation method thereof. The traditional Chinese medicine composition is prepared with costustoot, fructus amomi or Chinese eaglewood, bitter orange or immature bitter orange, sandalwood, rhubarb, officinal magnolia bark, musk, defatted croton seed powder, Chinese date, Szechuan lovage rhizome and the like. Clinically, the traditional Chinese medicine composition mainly treats diseases such as acute diarrhea and irritable bowel syndrome.

The invention discloses a traditional Chinese medicine composition for treating a uterus cancer. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 20-100 parts of oroxylum indicum, 50-200 parts of oroxylum indicum, 20-100 parts of arundina graminifolia, 50-200 parts of pingwo (Chinese character) gynura segetum and 100-400 parts of dracaena draco linn. In addition, the invention further simultaneously discloses a preparation method and an application of the traditional Chinese medicine composition. The traditional Chinese medicine composition disclosed by the invention has a good treatment effect on the uterus cancer, a stomach cancer and an esophagus cancer.

The medicine for treating cervical spondylosis as one kind of orally taken Chinese medicine powder is prepared with scorpion, centipede, fleeceflower root, peach kernel, safflower and other five kinds of Chinese medicinal materials in certain weight proportion, and through sorting material, stoving, crushing, 100-120 mesh sieving and steps of traditional Chinese medicine preparing process. The clinical practice on over ten thousand cases shows that the medicine has fast acting, determined curative effect, high efficiency, less recurrence and no obvious toxic side effect in treating various kinds of cervical spondylosis.

The invention discloses a traditional Chinese medicine composition for treating chronic hepatitis B. The traditional Chinese medicine composition is composed of the following traditional Chinese medicines by weight: 5-18g of radix bupleuri, 9-26g of bitter orange, 7-19g of rhizoma corydalis, 8-21g of radix curcumae, 3-9g of elecampane, 6-15g of rhizoma cyperi, 15-40g of Astragalus membranaceus, 5-18g of radix pseudostellariae, 9-16g of white atractylodes rhizome, 11-27g of hyacinth bean, 10-20g of Tuckahoe, 8-45g of giant knot weed, and 18-40g of rhizoma smilacis glabrae, furthermore, the traditional Chinese medicine composition is composed of the following traditional Chinese medicines by weight: 6-13g of radix bupleuri, 12-19g of bitter orange, 9-16g of rhizoma corydalis, 10-17g of radix curcumae, 5-7g of elecampane,7-12g of rhizoma cyperi, 18-30g of Astragalus membranaceus, 8-16g of radix pseudostellariae, 11-15g of white atractylodes rhizome, 16-23g of hyacinth bean, 14-18g of Tuckahoe, 12-30g of giant knot weed, and 23-36g of rhizoma smilacis glabrae.

The invention discloses a traditional Chinese medicine for treating cough and method for preparing the same. The traditional Chinese medicine for treating cough is prepared by using the following raw medicinal materials in parts by weight: 25 to 35 parts of mulberry leaf, 25 to 35 parts of bitter apricot seed, 15 to 25 parts of great burdock achene, 5 to 15 parts of hogfennel root, 5 to 15 parts of peppermint, 5 to 15 parts of dried tangerine peel, 5 to 15 parts of platycodon root and 3 to 8 parts of liquorice root. The dried tangerine peel and the peppermint are subjected to volatile oil extraction and are included by HP-beta-cyclodextrin to obtain inclusion compounds, the great burdock achene and the hogfennel root are subjected to ethanol reflux extraction, and the mulberry leaf, the bitter apricot seed, the platycodon root, the liquorice root and medicine residues are subjected to water decoction to obtain a preparation. The traditional Chinese medicine for treating cough has an effect of treating cough, especially cough caused by wind-heat affecting lung; by adopting natural plants, no obvious toxic and side effects are found in study, the safety is high, and the product can be prepared into pharmaceutical orally-taken liquid and can be widely used.

The invention relates to a Chinese medicine composite for treating gastrointestinal diseases and a preparation method thereof, which is made into tablets by least ten ingredients of costustoot, agilawood, bitter orange, sandalwood, rheum officinale, twolobed officinal magnolia bark, moschus, semen crotonis pulveratum, fructus jujubae and ligusticum chuanxiong, and the like. The Chinese medicine composite is clinically used for treating acute diarrhea and irritable bowel syndrome, and the like.

The invention discloses a traditional Chinese medicine preparation for treating psoriasis. The traditional Chinese medicine preparation is prepared from the following crude drugs in parts by weight: 25 to 35g of cornu bubali, 9 to 12 parts of radix scutellariae, 10 to 12 parts of poria cocos, 12 to 15 parts of cortex moutan radicis, 9 to 15 parts of cortex dictamni, 9 to 12 parts of Chinese angelica, 10 to 30 parts of crude flos sophorae, 10 to 15 parts of radix salviae miltiorrhizae, 10 to 30 parts of radix rehmanniae, 6 to 9 parts of radix clematidis, and 3 to 10 parts of liquorice root. In the treatment process, the traditional Chinese medicine preparation is conventionally decocted by water twice, one dose is taken each day respectively at morning and evening, about 100ml is taken each time, and the traditional Chinese medicine preparation is continuously taken for 10 days as one treatment course. The traditional Chinese medicine preparation has the advantages that the effects of clearing heat, cooling blood and detoxifying, and removing blood stasis, eliminating freckle and relieving itching are realized, the immunity can be regulated, and the effect of supporting the healthy energy is realized, so that the good effect is obtained; the effect of treating the psoriasis is obvious, and any side effect is avoided in the treatment process; the price of each raw material is low, so that the traditional Chinese medicine preparation is suitable for common populations and is suitable for popularizing and applying.

The invention relates to a volatile oil of Artemisia frigida var. atropurpurea. The volatile oil is a flaxen transparent liquid which has full aroma, and comprises the following main chemical components by weight percentage: 20-40% of camphor, 15-30% of encalyptole, 5-10% of 6-methyl-2-ethenyl-1,3-heptadiene aldehyde, 1-5% of menthenol, 1-5% of bridge-ring terpenone, 1-5% of camphene, 1-5% of 1R-alpha-pinene, 1-5% of demethyl eugenol, 1-5% of alpha-terpineol, 1-5% of borneol, 1-5% of beta-myrcene and 0.1-5% of thymol. Meanwhile, the invention further discloses a preparation method of the volatile oil which has high extraction rate and simple process flows. The volatile oil of Artemisia frigida var. atropurpurea can be applied to treating rhinitis because of bacteriostatic and antiphlogistic active components thereof.

The present invention discloses a medicine for curing respiratory diseases, in particular to a medicine for curing chronic bronchitis, emphysema and other diseases and a preparation method thereof. The present invention takes gecko, suncured ginseng, radix astragali, sichuan fritillary bulb, shizandra berry, mulberry root bark, bitter almond, figwort root, angelica, white peony, pachyma cocos and liquorice as the raw materials and then manufactures raw materials into powder or capsules in proportion after pulverizing, chipping, decocting with water for three times, and the like, according to different properties of the medicinal materials. The present invention has the advantages of significant curative effect, wide application, easy access to raw materials and low cost.