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Chinese medicine composite for treating gastrointestinal diseases and preparation method thereof

A technology of gastrointestinal diseases and compositions, which is applied in the field of traditional Chinese medicine composition tablets for the treatment of gastrointestinal diseases and its preparation, and can solve problems such as endocrine system harm, harm to fetal and infant health, mercury harm, etc.

Active Publication Date: 2010-07-07
津药达仁堂集团股份有限公司乐仁堂制药厂
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But its formula contains cinnabar, its function is to calm the nerves, but cinnabar contains mercury, which is very harmful to the human body. It is a subtle and continuous absorption process. Long-term exposure to mercury will cause chronic poisoning: Harmful to human nerves, digestion, endocrine system and kidneys; people with neurasthenia may cause symptoms such as headache, dizziness, insomnia, memory loss, and general fatigue; and long-term exposure to mercury by pregnant and breastfeeding women may also harm the fetus and baby's health
In addition, mercury-containing medicines are subject to certain restrictions when exported to other countries. For example, Singapore requires that the mercury content must be less than 0.5ppm, while the requirements for some European countries are more stringent.

Method used

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  • Chinese medicine composite for treating gastrointestinal diseases and preparation method thereof
  • Chinese medicine composite for treating gastrointestinal diseases and preparation method thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0144] a. Take the following weight ratio raw materials: Muxiang 150g, Agarwood 150g, Citrus aurantium 150g, Sandalwood 90g, Rhubarb 90g, Magnolia officinalis 150g, Artificial musk 4.5g, Croton cream 60g, Jujube 500g, Chuanxiong 90g for use;

[0145] b. Above ten flavors, croton cream and musk were crushed into fine powder; rhubarb was crushed into fine powder; volatile oil was extracted from woody, agarwood, and sandalwood for later use, the extract was filtered, and the rest of chuanxiong, citrus aurantium, magnolia, jujube Wait for the four herbs to add water to decoc 2 times, 1 hour each time, combine the decoction, filter, concentrate, dry, pulverize into fine powder, mix with croton cream and musk powder, mix well, add rhubarb powder, starch, Microcrystalline cellulose, etc. are mixed and sieved to form granules, then volatile oils such as wood incense are added, mixed, and dried, an appropriate amount of magnesium stearate is added, mixed, and compressed, and it is ready.

Embodiment 2

[0147] a. Take the following weight ratio APIs: Woody 600g, Agarwood 600g, Fructus Aurantii 600g, Sandalwood 360g, Rhubarb 360g, Magnolia officinalis 600g, Artificial Musk 18g, Croton Cream 240g, Jujube 2000g, Chuanxiong 360g for spare;

[0148] b. Above ten flavors, croton cream and musk were crushed into fine powder; rhubarb was crushed into fine powder; volatile oil was extracted from woody, agarwood, and sandalwood for later use, the extract was filtered, and the rest of chuanxiong, citrus aurantium, magnolia, jujube Wait for the four herbs to add water and decoct 4 times, 4 hours each time, combine the decoction, filter, concentrate, dry, pulverize into fine powder, mix with croton cream and musk powder, mix well, add rhubarb powder, starch, Microcrystalline cellulose, etc. are mixed and sieved to form granules, then volatile oils such as wood incense are added, mixed, and dried, an appropriate amount of magnesium stearate is added, mixed, and compressed, and it is ready.

Embodiment 3

[0150] a. Take the following weight ratio APIs: Woody 200g, Agarwood 150g, Fructus aurantii 600g, Sandalwood 360g, Rhubarb 90g, Magnolia officinalis 200g, Musk 10g, Croton Cream 80g, Jujube 1500g, Chuanxiong 300g for use;

[0151] b. Above ten flavors, croton cream and musk were crushed into fine powder; rhubarb was crushed into fine powder; volatile oil was extracted from woody, agarwood, and sandalwood for later use, the extract was filtered, and the rest of chuanxiong, citrus aurantium, magnolia, jujube Wait for the four herbs to be decocted 3 times with water for 2 hours each time. Combine the decoction, filter, concentrate, dry, pulverize into fine powder, mix with croton cream and musk powder, mix well, add rhubarb powder, starch, Microcrystalline cellulose, etc. are mixed and sieved to form granules, then volatile oils such as wood incense are added, mixed, and dried, an appropriate amount of magnesium stearate is added, mixed, and compressed, and it is ready.

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Abstract

The invention relates to a Chinese medicine composite for treating gastrointestinal diseases and a preparation method thereof, which is made into tablets by least ten ingredients of costustoot, agilawood, bitter orange, sandalwood, rheum officinale, twolobed officinal magnolia bark, moschus, semen crotonis pulveratum, fructus jujubae and ligusticum chuanxiong, and the like. The Chinese medicine composite is clinically used for treating acute diarrhea and irritable bowel syndrome, and the like.

Description

Technical field [0001] The invention relates to the field of medicine, in particular to a traditional Chinese medicine composition tablet for treating gastrointestinal diseases and a preparation method thereof. Background technique [0002] Diarrhea can be divided into infectious and non-infectious categories. Infectious diarrhea is divided into bacterial infection and viral infection; non-infectious diarrhea can be caused by a variety of reasons such as improper diet, food allergies, changes in lifestyle, climate mutations and even emotional stress. Chinese medicine believes that diarrhea refers to increased bowel movements, thin stools, and even water samples. The main pathological changes of diarrhea are the spleen, stomach and large and small intestines. The causes of the disease include feelings of external evils, food injuries, discordance of seven emotions, internal resistance of damp evil, and weakness of viscera. Clinically, damp pathogens can cause cold and dampness ...

Claims

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Application Information

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IPC IPC(8): A61K36/835A61P1/00A61P1/08A61P1/12A61P1/14A61K31/122
CPCY02A50/30
Inventor 陈坚王磊袁雪海王伟杨瑾王春晨郝忻
Owner 津药达仁堂集团股份有限公司乐仁堂制药厂
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