Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Traditional Chinese medicine for treating cough and method for preparing same

The technology of traditional Chinese medicine and raw material medicine, which is applied in the field of traditional Chinese medicine for treating cough and its preparation field, can solve the problems of large side effects of western medicine, and achieve the effect of expectorant, anti-inflammatory and high safety.

Inactive Publication Date: 2016-12-21
NANJING HOSPITAL OF T C M +1
View PDF2 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The invention provides a traditional Chinese medicine for treating cough with remarkable curative effect and little side effects and a preparation method thereof, which solves the problems of large side effects of existing western medicines and the like

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Traditional Chinese medicine for treating cough and method for preparing same
  • Traditional Chinese medicine for treating cough and method for preparing same
  • Traditional Chinese medicine for treating cough and method for preparing same

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Step 1: Weigh 180g mulberry leaves, 180g bitter almonds, 120g burdock seeds, 90g peucedanum, 60g mint, 60g bellflower, 60g tangerine peel, and 30g licorice.

[0022] Step 2: Take mint and tangerine peel, crush them into coarse powder, add 1200g of water, soak for 0.5 hours, steam distillation for 7 hours, collect volatile oil, add 8 times the amount of HP-β-CD to the volatile oil, and prepare clathrate by grinding The inclusion compound was ground for 95 minutes, and the inclusion compound was vacuum-dried at 40°C for later use.

[0023] Step 3: Take Burdock Fructus and Peucedanum Peucedanum, add 70% ethanol with a volume concentration of 15 times the total weight of the two raw materials, and extract by reflux three times, each time for 1.5 hours, combine the extracts, filter, and concentrate the filtrate under reduced pressure to recover Ethanol, concentrated until there is no alcohol smell, to obtain the concentrated solution of alcohol extraction.

[0024] Step 4: ...

Embodiment 2

[0025] Embodiment 2: pharmacodynamic experiment

[0026] (1) Cough test

[0027] 1. Method

[0028] Experimental samples were prepared according to Example 1 of the present invention. Take 48 ICR mice, weighing 20-22 g, half male and half male. Divide into 4 groups at random according to body weight: be respectively (1) blank control group: NS 10ml / kg; (2) Ganmao cough granule group: 5g / kg; (3) low dosage group of the present invention: 2.8g / kg; (4) ) High dose group of the present invention: 5.6g / kg. Each group was intragastrically administered with the above-mentioned dose at a volume of 20ml / kg, once a day, for 6 consecutive days. 30 minutes after the last administration, put the mouse in an inverted 500ml beaker, put a cotton ball in it, draw 0.2ml of ammonia water with a 1ml syringe, inject the cotton ball, quickly invert the beaker, observe and record the cough latency of the mouse and cough within 3 minutes frequency.

[0029] 2. Results

[0030] Experimental res...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a traditional Chinese medicine for treating cough and method for preparing the same. The traditional Chinese medicine for treating cough is prepared by using the following raw medicinal materials in parts by weight: 25 to 35 parts of mulberry leaf, 25 to 35 parts of bitter apricot seed, 15 to 25 parts of great burdock achene, 5 to 15 parts of hogfennel root, 5 to 15 parts of peppermint, 5 to 15 parts of dried tangerine peel, 5 to 15 parts of platycodon root and 3 to 8 parts of liquorice root. The dried tangerine peel and the peppermint are subjected to volatile oil extraction and are included by HP-beta-cyclodextrin to obtain inclusion compounds, the great burdock achene and the hogfennel root are subjected to ethanol reflux extraction, and the mulberry leaf, the bitter apricot seed, the platycodon root, the liquorice root and medicine residues are subjected to water decoction to obtain a preparation. The traditional Chinese medicine for treating cough has an effect of treating cough, especially cough caused by wind-heat affecting lung; by adopting natural plants, no obvious toxic and side effects are found in study, the safety is high, and the product can be prepared into pharmaceutical orally-taken liquid and can be widely used.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine for treating cough and its preparation method and application. Background technique [0002] Cough refers to a disease of the lung system in which the lungs fail to ventilate and descend, and the lung qi rises upwards, making a coughing sound, or coughing up sputum. Traditional Chinese medicine believes that coughing is caused by exogenous evils invading the lungs or visceral dysfunction caused by lung failure and lung qi upside down. Zhang Jingyue, a physician in the Ming Dynasty, first classified cough into two major factors: exogenous pathogenic factors and internal injuries. kind. According to modern medical theory, cough is a defense mechanism of the body, which is beneficial to remove respiratory secretions and harmful substances, and prevent the spread of respiratory infection. Modern medical research has confirmed that...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/752A61P11/14
CPCA61K36/23A61K36/28A61K36/346A61K36/484A61K36/534A61K36/605A61K36/736A61K36/752A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 谈瑄忠
Owner NANJING HOSPITAL OF T C M
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com