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Soft capsules for suppressing cold and preparation method and application thereof

A technology of soft capsules and mullein, which is applied in capsule delivery, pharmaceutical formulations, medical preparations containing active ingredients, etc., can solve problems such as the cause of the disease is not completely clear, and achieve the effect of no toxic side effects, reasonable design, and definite curative effect

Inactive Publication Date: 2015-03-25
NANJING ZHENGLIANG MEDICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the exact cause is still unclear

Method used

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  • Soft capsules for suppressing cold and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Example 1: Get 18g of Mullein grass, 22g of Lantern plant, 8g of safflower plus 12 times the amount of 70% ethanol for reflux extraction twice, each time for 2 hours, combine the extracts, filter, and concentrate the filtrate under reduced pressure to a thick extract , vacuum-dried, and pulverized to obtain dry extract powder; in addition, menthol 5g was crushed into fine powder, mixed with the above-mentioned dry extract powder, passed through a 100-mesh sieve, added an appropriate amount of vegetable oil, mixed, ground with a colloid mill, cooled to room temperature, Press into 1000 capsules, dry, degrease, and dry to obtain soft capsules.

Embodiment 2

[0022] Example 2: Get 20 g of Mullinus chinensis, 20 g of Lantern plant, 10 g of safflower plus 12 times the amount of 70% ethanol for reflux extraction twice, each time for 2 hours, combine the extracts, filter, and concentrate the filtrate under reduced pressure to a thick extract , vacuum-dried, and crushed to obtain dry extract powder; in addition, menthol 4g was crushed into fine powder, mixed with the above-mentioned dry extract powder, passed through a 100-mesh sieve, added an appropriate amount of vegetable oil, mixed, ground with a colloid mill, cooled to room temperature, Press into 1000 capsules, dry, degrease, and dry to obtain soft capsules.

Embodiment 3

[0023] Example 3: Get 22 g of Mullinus chinensis, 18 g of Lantern plant, 12 g of safflower plus 12 times the amount of 70% ethanol for reflux extraction twice, each time for 2 hours, combine the extracts, filter, and concentrate the filtrate under reduced pressure to a thick extract , vacuum-dried, and crushed to obtain dry extract powder; in addition, 3 g of menthol was crushed into fine powder, mixed with the above-mentioned dry extract powder, passed through a 100-mesh sieve, added an appropriate amount of vegetable oil, mixed, ground with a colloid mill, cooled to room temperature, Press into 1000 capsules, dry, degrease, and dry to obtain soft capsules.

[0024] 3. The present invention's test data on antitussive efficacy

[0025] 3.1 Animals: guinea pigs, half male and half female, weighing about 160-200g, provided by Qinglongshan Animal Breeding Farm, Tangshan, Jiangning County, experimental animal production license SCXK (Su) 2002-0004, experimental animal use license:...

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PUM

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Abstract

The invention provides soft capsules for suppressing a cold. The soft capsules are prepared from the following raw material medicines in parts by weight: 18-22 parts of Duthiea brachypodium, 18-22 parts of peruvian groundcherry herb, 8-12 parts of flowers carthami and 3-5 parts of menthol. The raw material medicines are prepared into soft capsules by adopting a corresponding preparation method. The soft capsules have the effect of suppressing the cold and are used for treating asthma and acute and chronic bronchitis.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a soft capsule for suppressing cough, a preparation method and application thereof. Background technique [0002] Bronchitis is generally divided into acute and chronic. Acute bronchitis is an acute inflammation of the bronchial mucosa caused by viral or bacterial infection, physical or chemical stimulation or allergic reaction, and is generally a self-limiting disease. The main reason for chronic bronchitis is chronic non-specific inflammation of the bronchi caused by superinfection of viruses and bacteria. Sudden drop in temperature, spasm and ischemia of small respiratory vessels, decreased defense function, etc. are conducive to pathogenesis; chronic stimuli such as smoke, dust, and air pollution can also cause disease; smoking can cause bronchospasm, mucous membrane variation, decreased ciliary movement, and increased mucus secretion, which is conducive ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/81A61K9/48A61P11/14A61P11/06A61P11/00A61K31/045
CPCA61K36/899A61K9/4858A61K31/045A61K36/286A61K36/81A61K2236/333A61K2236/39A61K2236/51A61K2236/53
Inventor 卞毓平
Owner NANJING ZHENGLIANG MEDICAL TECH
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