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Traditional Chinese medicine composition for treating gastrointestinal diseases and preparation method thereof

A technology for gastrointestinal diseases and compositions, which is applied in the field of traditional Chinese medicine compositions for treating gastrointestinal diseases and its preparation, and can solve problems such as mercury hazards, fetal and infant health hazards, and endocrine system hazards

Active Publication Date: 2010-06-30
TIANJIN ZHONGXIN PHARMA GRP CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But its formula contains cinnabar, its function is to calm the nerves, but cinnabar contains mercury, which is very harmful to the human body. It is a subtle and continuous absorption process. Long-term exposure to mercury will cause chronic poisoning: Harmful to human nerves, digestion, endocrine system and kidneys; people with neurasthenia may cause symptoms such as headache, dizziness, insomnia, memory loss, and general fatigue; and long-term exposure to mercury by pregnant and breastfeeding women may also harm the fetus and baby's health
In addition, mercury-containing medicines are subject to certain restrictions when exported to other countries. For example, Singapore requires that the mercury content must be less than 0.5ppm, while the requirements for some European countries are more stringent.

Method used

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  • Traditional Chinese medicine composition for treating gastrointestinal diseases and preparation method thereof
  • Traditional Chinese medicine composition for treating gastrointestinal diseases and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0119] a. get the following raw materials by weight: clove 150g, agarwood 150g, citrus aurantium 150g, sandalwood 90g, rhubarb 90g, magnolia bark 150g, artificial musk 4.5g, croton cream 60g, jujube 500g, chuanxiong 90g for subsequent use;

[0120] b. For the above ten herbs, croton cream and musk are pulverized into fine powder for use; clove, agarwood, sandalwood, citrus aurantium, magnolia, chuanxiong, rhubarb are pulverized, CO 2 Supercritical extraction; take the extract, add an appropriate amount of anhydrous ethanol to dissolve, use an appropriate amount of β-CD for inclusion, and dry to obtain an inclusion compound, which is for later use; extract the drug residues after the supercritical extraction with ethanol twice, and combine them The secondary filtrate is recovered with ethanol and concentrated for subsequent use; the jujube is decocted with water for the second time, and filtered; the filtrate is combined, concentrated, mixed with the above-mentioned alcohol extr...

Embodiment 2

[0122] a. Get the following raw materials in weight ratio: clove 100g, agarwood 600g, citrus aurantium 600g, sandalwood 360g, rhubarb 360g, magnolia bark 600g, musk 18g, croton cream 240g, jujube 2000g, chuanxiong 360g for subsequent use;

[0123] b. Top ten herbs, croton cream and musk are crushed into fine powder for later use; six herbs such as clove, agarwood, sandalwood, citrus aurantium, Magnolia officinalis and Chuanxiong are crushed into coarse powder, add water, soak, decoct and distill in water, and collect volatile oil , after wrapping with β-CD, set aside; the decoction is filtered, the filtrate is concentrated for later use, the dregs and rhubarb coarse powder are extracted twice with ethanol, and filtered; the secondary filtrates are combined, concentrated, dried, and set aside; take jujube, add Decoction with water for the second time, filter; combine the secondary filtrate, concentrate, dry, pulverize the above-mentioned drying into fine powder, mix with croton ...

Embodiment 3

[0125] a. Take the following raw materials by weight: 200g of cloves, 150g of agarwood, 600g of citrus aurantium, 360g of sandalwood, 90g of rhubarb, 200g of Magnolia officinalis, 10g of musk, 80g of croton cream, 1500g of jujube, and 300g of Chuanxiong;

[0126] b. For the above ten flavors, croton cream and musk are respectively crushed into fine powder; the other eight flavors such as clove and agarwood are boiled twice with water for 2 hours each time, combined with the decoction, filtered, and concentrated into a thick paste. Add croton cream and musk powder to the cream, mix well and set aside; take an appropriate amount of polyethylene glycol 6000, heat to melt, add the above thick cream, croton cream and musk powder mixture, mix well, and use a dripping rate of 85 to 90 drops / min, drop into the cooled liquid paraffin to make drop pills, that is, it is obtained.

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Abstract

The invention relates to a traditional Chinese medicine composition for treating gastrointestinal diseases and a preparation method thereof. The traditional Chinese medicine composition is prepared from tens of traditional Chinese herbs of costustoot, agilawood, fructus aurantii, sanders, rheum officinale, mangnolia officinalis, muak, defatted croton seed powder, date and ligusticum wallichii. The traditional Chinese medicine composition is mainly used for treating diseases of acute diarrhea, irritable bowel syndrome and the like in clinic.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a traditional Chinese medicine composition for treating gastrointestinal diseases and a preparation method thereof. Background technique [0002] Diarrhea can be divided into infectious and non-infectious categories. Infectious diarrhea is further divided into bacterial infection and viral infection; non-infectious diarrhea can be caused by various reasons such as improper diet, food allergies, changes in living patterns, sudden changes in climate and even emotional stress. The motherland medicine believes that diarrhea refers to the increased frequency of defecation, the stool is thin, and even watery. The main lesions of diarrhea lie in the spleen, stomach and large intestine. The causes of the disease include feeling external pathogens, injury from diet, disharmony of the seven emotions, internal resistance of dampness pathogens, and weakness of the viscera. The pathogenesis of damp...

Claims

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Application Information

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IPC IPC(8): A61K36/835A61P1/00A61P1/08A61P1/12A61P1/14A61K31/122
CPCY02A50/30
Inventor 陈坚王磊袁学海王伟杨瑾王春晨郝忻
Owner TIANJIN ZHONGXIN PHARMA GRP CO LTD
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