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Traditional Chinese medicine for treating constipation, and preparation method and application thereof

A technology for treating constipation and traditional Chinese medicine, which is applied in the direction of medical formulas, medical preparations containing active ingredients, drug combinations, etc., can solve the problems of high cost, large toxic and side effects, etc., and achieve high safety, increase body weight, and good therapeutic effects Effect

Active Publication Date: 2013-12-25
NANJING HOSPITAL OF T C M +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The invention provides a traditional Chinese medicine for treating constipation with remarkable curative effect and little side effects, its preparation method and application, and solves the technical problems of large toxic and side effects and high cost in the existing western medicine technology and traditional Chinese medicine preparation technology

Method used

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  • Traditional Chinese medicine for treating constipation, and preparation method and application thereof
  • Traditional Chinese medicine for treating constipation, and preparation method and application thereof
  • Traditional Chinese medicine for treating constipation, and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0043] Step 1: Weigh 500g of Heishun tablets, 300g of cinnamon, 300g of Epimedium, 600g of Magnolia officinalis made from ginger, 300g of Scallops, 700g of Pueraria mirifica, and 500g of Poria cocos.

[0044] Step 2: Take cinnamon, add 5000g of water, soak for 1 hour, steam distillation for 3 hours, distillation temperature is 100°C, collect volatile oil, add 8 times the amount of β-cyclodextrin to the volatile oil, and prepare clathrate by saturated aqueous solution method , the inclusion temperature is 30°C, the electric stirring speed is 120r / min, the inclusion compound is 0.5 hour, and the inclusion compound is vacuum-dried at 40°C for later use.

[0045] The third step: take Pueraria lobata, Magnolia officinalis and Allium scallions, add ethanol with 80% volume concentration of 12 times the total mass of the three raw materials, and extract in two refluxes, each time for 2 hours, combine the extracts, filter, and decompress the filtrate Concentrate to recover ethanol, con...

Embodiment 2

[0048] Step 1: Weigh 600g of Heishun tablets, 200g of cinnamon, 400g of Epimedium, 300g of Magnolia officinalis made from ginger, 400g of Scallops, 600g of Pueraria mirifica, and 400g of Poria cocos.

[0049] Step 2: Take cinnamon, add 5000g of water, soak for 1 hour, steam distillation for 3 hours, distillation temperature is 100°C, collect volatile oil, add 8 times the amount of β-cyclodextrin to the volatile oil, and prepare clathrate by saturated aqueous solution method , the inclusion temperature is 30°C, the electric stirring speed is 120r / min, the inclusion compound is 0.5 hour, and the inclusion compound is vacuum-dried at 40°C for later use.

[0050] Step 3: Take Pueraria lobata, Magnolia officinalis and Allium scallops, add ethanol with 80% volume concentration of 12 times the total mass of the three raw materials, and extract in two refluxes, each time for 2 hours, combine the extracts, filter, and decompress the filtrate Concentrate to recover ethanol, concentrate ...

Embodiment 3

[0053] Step 1: Weigh 700g of Heishun tablets, 100g of cinnamon, 500g of Epimedium, 200g of Magnolia officinalis made from ginger, 500g of Scallops, 500g of Pueraria mirifica, and 500g of Poria cocos.

[0054] Step 2: Take cinnamon, add 5000g of water, soak for 1 hour, steam distillation for 3 hours, distillation temperature is 100°C, collect volatile oil, add 8 times the amount of β-cyclodextrin to the volatile oil, and prepare clathrate by saturated aqueous solution method , the inclusion temperature is 30°C, the electric stirring speed is 120r / min, the inclusion compound is 0.5 hour, and the inclusion compound is vacuum-dried at 40°C for later use.

[0055] Step 3: Take Pueraria lobata, Magnolia officinalis and Allium scallops, add ethanol with 80% volume concentration of 12 times the total mass of the three raw materials, and extract in two refluxes, each time for 2 hours, combine the extracts, filter, and decompress the filtrate Concentrate to recover ethanol, concentrate ...

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Abstract

The invention discloses a traditional Chinese medicine for treating the constipation, and a preparation method and an application thereof. The traditional Chinese medicine is prepared by using the following raw medicines, by mass, 25-35 parts of Radix aconiti lateralis preparata, 5-15 parts of cinnamon, 15-25 parts of epimeddium, 10-20 parts of cortex magnoliae officinalis, 15-25 parts of Longstamen Onion Bulb, 25-35 parts of Radix Puerariae and 15-25 parts of Poria cocos. The preparation method comprises the following steps: extracting volatile oil from the cinnamon, carrying out clathration by beta-cyclodextrin to obtain a clathrate, and refluxing other traditional Chinese medicines by ethanol to prepare a preparation. The traditional Chinese medicine can be used for treating the constipation, especially spleen and kidney yang deficiency type constipation; researches show that the traditional Chinese medicine adopting natural plants has no obvious toxic side effects and has high security; and the traditional Chinese medicine can be processed to prepare a pharmaceutical tablet, capsule or granule to be widely used.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine for treating constipation and its preparation method and application. Background technique [0002] Constipation is a common clinical symptom rather than a disease. It mainly refers to decreased frequency of defecation, decreased amount of feces, dry feces, and laborious defecation. When two or more of the above symptoms are present at the same time, it can be diagnosed as symptomatic constipation. Usually, the frequency of defecation is reduced. Generally, one defecation every 2 to 3 days or longer is considered constipation. The survey results of a group of healthy people show that the habit of defecation is mostly 1-2 times a day or once a day, and the stools are mostly shaped or soft; a small number of healthy people can defecate up to 3 times a day, or 3 times a day. Once a day, the stool is semi-formed or sausage-like h...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8962A61P1/10
Inventor 谈瑄忠丁署琴王蕾毛春芹李林陆兔林陈寅生丁义江
Owner NANJING HOSPITAL OF T C M
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