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Traditional Chinese medicine composition for treating gastrointestinal disease and preparation method thereof

A technology for gastrointestinal diseases and compositions, which is applied in the field of traditional Chinese medicine compositions for treating gastrointestinal diseases and its preparation, and can solve problems such as endocrine system harm, fetal and infant health harm, mercury harm, etc.

Active Publication Date: 2010-06-30
津药达仁堂集团股份有限公司乐仁堂制药厂
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But its formula contains cinnabar, its function is to calm the nerves, but cinnabar contains mercury, which is very harmful to the human body. It is a subtle and continuous absorption process. Long-term exposure to mercury will cause chronic poisoning: Harmful to human nerves, digestion, endocrine system and kidneys; people with neurasthenia may cause symptoms such as headache, dizziness, insomnia, memory loss, and general fatigue; and long-term exposure to mercury by pregnant and breastfeeding women may also harm the fetus and baby's health
In addition, mercury-containing medicines are subject to certain restrictions when exported to other countries. For example, Singapore requires that the mercury content must be less than 0.5ppm, while the requirements for some European countries are more stringent.

Method used

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  • Traditional Chinese medicine composition for treating gastrointestinal disease and preparation method thereof
  • Traditional Chinese medicine composition for treating gastrointestinal disease and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0119] a. Take the following raw materials in weight ratio: 150g of woody fragrance, 150g of green bark, 150g of citrus aurantii, 90g of sandalwood, 90g of rhubarb, 150g of Magnolia officinalis, 4.5g of musk, 60g of croton cream, 500g of jujube, 90g of chuanxiong for later use;

[0120] b. The above ten herbs, croton cream and musk are crushed into fine powder for later use; 2 Supercritical extraction; take the extract, add an appropriate amount of absolute ethanol to dissolve, add an appropriate amount of β-CD for clathrate, and dry to obtain the clathrate for later use; ethanol extract the dregs of the above supercritical extract twice, combine Take the filtrate twice, recover the ethanol and concentrate it for later use; take the jujube and add water to decoct it twice, and filter; combine the filtrate, concentrate, mix with the above-mentioned alcohol extract concentrate, dry, grind into fine powder, and then mix with clathrate, croton Cream and musk are sieved and mixed, ...

Embodiment 2

[0122] a. Take the following raw materials in weight proportions: 300g Cyperus cyperi, 600g Cyperus cyperi, 600g Citrus aurantii, 360g sandalwood, 360g rhubarb, 600g Magnolia officinalis, 18g artificial musk, 240g croton cream, 2000g jujube, 360g Chuanxiong for later use;

[0123] b. The top ten medicines, croton cream and musk are crushed into fine powder for later use; the six medicines such as woody incense, Cyperus cyperi, sandalwood, Citrus aurantium, Magnolia officinalis, Chuanxiong are crushed into coarse powder, add water, soak, decoct and distill. Collect the volatile oil, wrap it with β-CD, and set aside; filter the decoction, concentrate the filtrate for later use, reflux extract the dregs and rhubarb coarse powder with ethanol twice, and filter; combine the second filtrate, concentrate, dry, and set aside; take jujube , add water to decoct twice, filter; combine the second filtrates, concentrate, dry, dry and pulverize into fine powder, mix with croton cream and mus...

Embodiment 3

[0125] a. Take the following raw materials in weight ratio: 600g of woody fragrance, 150g of green bark, 600g of citrus aurantii, 360g of sandalwood, 90g of rhubarb, 200g of Magnolia officinalis, 10g of musk, 80g of croton cream, 1500g of jujube, 300g of chuanxiong for later use;

[0126] b. The above raw materials, croton cream and musk are pulverized into fine powder respectively; the rest of the raw materials are pulverized into fine powder, compounded with croton cream and musk powder, mixed, sieved, and set aside; watered into pills, dried at low temperature, and obtained .

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Abstract

The invention relates to a traditional Chinese medicine composition for treating gastrointestinal disease and a preparation method thereof. The traditional Chinese medicine composition is prepared from elecampane, pericarpium citri reticulatae viride or rhizoma cyperi, fructus aurantii, sandalwood, rheum officinale, mangnolia officinalis, muscat, defatted croton seed powder, fructus Zizyphi and ligusticum wallichii. The invention is mainly used for treating diseases such as acute diarrhea, irritable bowel syndrome and the like in clinic.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a traditional Chinese medicine composition for treating gastrointestinal diseases and a preparation method thereof. Background technique [0002] Diarrhea can be divided into infectious and non-infectious categories. Infectious diarrhea is divided into bacterial infection and viral infection; non-infectious diarrhea can be caused by various reasons such as improper diet, food allergies, changes in life patterns, sudden changes in climate, and even emotional stress. Traditional Chinese medicine believes that diarrhea refers to increased frequency of defecation, clear and thin stool, or even watery. The main lesion of diarrhea lies in the spleen, stomach and large and small intestine. The causes of the disease include exogenous evils, injury from diet, disharmony of the seven emotions, internal resistance of dampness, and weakness of viscera. The pathogenicity of dampness seen clinically...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8905A61K36/752A61P1/00A61P1/08A61P1/12A61P1/14A61K31/122
CPCY02A50/30
Inventor 陈坚王磊袁学海王伟杨瑾王春晨郝忻
Owner 津药达仁堂集团股份有限公司乐仁堂制药厂
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