Gastrointestinal disease-treating traditional Chinese medicine composition containing costustoot and preparation method thereof

A technology for gastrointestinal diseases and compositions is applied in the field of traditional Chinese medicine compositions containing woody incense for the treatment of gastrointestinal diseases and the field of preparation thereof, which can solve the problems of mercury harm, harm to the health of fetuses and infants, endocrine system harm and the like

Active Publication Date: 2012-01-25
津药达仁堂集团股份有限公司乐仁堂制药厂
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But its formula contains cinnabar, its function is to calm the nerves, but cinnabar contains mercury, which is very harmful to the human body. It is a subtle and continuous absorption process. Long-term exposure to mercury will cause chronic poisoning: Harmful to human nerves, digestion, endocrine system and kidneys; people with neurasthenia may cause symptoms such as headache, dizziness, insomnia, memory loss, and general fatigue; and long-term exposure to mercury by pregnant and breastfeeding women may also harm the fetus and baby's health
In addition, mercury-containing medicines are subject to certain restrictions when exported to other countries. For example, Singapore requires that the mercury content must be less than 0.5ppm, while the requirements for some European countries are more stringent.

Method used

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  • Gastrointestinal disease-treating traditional Chinese medicine composition containing costustoot and preparation method thereof
  • Gastrointestinal disease-treating traditional Chinese medicine composition containing costustoot and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0119] a. Take the following raw materials in weight ratio: 150g of woody fragrance, 150g of amomum, 150g of citrus aurantii, 90g of sandalwood, 90g of rhubarb, 150g of magnolia officinalis, 4.5g of musk, 60g of croton cream, 500g of jujube, 90g of chuanxiong for later use;

[0120] b. The above ten herbs, croton cream and musk are crushed into fine powder for later use; 2 Supercritical extraction; take the extract, add an appropriate amount of absolute ethanol to dissolve, add an appropriate amount of β-CD for clathrate, and dry to obtain the clathrate for later use; ethanol extract the dregs of the above supercritical extract twice, combine Take the filtrate twice, recover the ethanol and concentrate it for later use; take the jujube and add water to decoct it twice, and filter; combine the filtrate, concentrate, mix with the above-mentioned alcohol extract concentrate, dry, grind into fine powder, and then mix with clathrate, croton Cream and musk are sieved and mixed, siev...

Embodiment 2

[0122] a. Take the following raw materials by weight: 300g of woody fragrance, 600g of agarwood, 600g of citrus aurantii, 360g of sandalwood, 360g of rhubarb, 600g of magnolia officinalis, 18g of musk, 240g of croton cream, 2000g of jujube, 360g of chuanxiong for later use;

[0123] b. Top ten medicines, croton cream and musk are crushed into fine powder for later use; woody fragrance, agarwood, sandalwood, citrus aurantii, magnolia officinalis, Chuanxiong and other six medicines are crushed into coarse powder, added with water, soaked, decocted and distilled, collected Volatile oil, after inclusion with β-CD, set aside; filter the decoction, concentrate the filtrate for later use, reflux extract the dregs and rhubarb coarse powder with ethanol twice, and filter; combine the second filtrate, concentrate, dry, and set aside; take jujube, Add water to decoct twice, filter; combine the second filtrates, concentrate, dry, dry and pulverize into fine powder, mix with croton cream an...

Embodiment 3

[0125] a. Take the following raw materials in weight ratio: 600g of woody fragrance, 150g of amomum, 600g of citrus aurantium, 360g of sandalwood, 90g of rhubarb, 200g of magnolia officinalis, 10g of artificial musk, 80g of croton cream, 1500g of jujube, 300g of chuanxiong for later use;

[0126] b. The above ten flavors, croton cream and musk are crushed into fine powder respectively; the other eight flavors such as woody fragrance and amomum are decocted twice with water, each time for 2 hours, and the decoctions are combined, filtered, and concentrated into a thick paste. Add croton cream and musk powder to the above thick cream, mix well, and set aside; take an appropriate amount of polyethylene glycol 6000, heat to melt, add the mixture of the above thick cream, croton cream, and musk powder, mix well, and use a dripping speed of 85-90 drop / min, drop into the cooled liquid paraffin to make drop pills, that is.

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Abstract

The invention relates to a gastrointestinal disease-treating traditional Chinese medicine composition containing costustoot and a preparation method thereof. The traditional Chinese medicine composition is prepared with costustoot, fructus amomi or Chinese eaglewood, bitter orange or immature bitter orange, sandalwood, rhubarb, officinal magnolia bark, musk, defatted croton seed powder, Chinese date, Szechuan lovage rhizome and the like. Clinically, the traditional Chinese medicine composition mainly treats diseases such as acute diarrhea and irritable bowel syndrome.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a traditional Chinese medicine composition containing woody wood for treating gastrointestinal diseases and a preparation method thereof. Background technique [0002] Diarrhea can be divided into infectious and non-infectious categories. Infectious diarrhea is divided into bacterial infection and viral infection; non-infectious diarrhea can be caused by various reasons such as improper diet, food allergies, changes in life patterns, sudden changes in climate, and even emotional stress. Traditional Chinese medicine believes that diarrhea refers to increased frequency of defecation, clear and thin stool, or even watery. The main lesion of diarrhea lies in the spleen, stomach and large and small intestine. The causes of the disease include exogenous evils, injury from diet, disharmony of the seven emotions, internal resistance of dampness, and weakness of viscera. The pathogenicity of da...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/835A61K36/9064A61P1/00A61P1/08A61P1/12A61P1/14A61K31/122
CPCY02A50/30
Inventor 陈坚王磊袁学海王伟杨瑾王春晨郝忻
Owner 津药达仁堂集团股份有限公司乐仁堂制药厂
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