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Contrast medium applicable to liver depression and spleen vacuity type irritable bowel syndrome

A technology for irritable bowel, liver stagnation and spleen deficiency, which is used in preparations, drug combinations, echo/ultrasound imaging agents, etc. for in vivo experiments

Inactive Publication Date: 2016-03-30
江瑞平
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] However, when patients with irritable bowel syndrome take contrast medium, it often occurs that the contrast medium reaches the ileocecal area within one or two hours. Normally, it should be within three to six hours, so that the contrast medium cannot be successfully contrasted.

Method used

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Effect test

Embodiment 1

[0039] This embodiment provides a contrast agent suitable for irritable bowel syndrome of liver depression and spleen deficiency type, which is composed of liposomes and microbubbles encapsulated in the liposomes, and the liposomes are composed of the following parts by weight: Components: 20 parts of lecithin, 55 parts of traditional Chinese medicine carrier; the traditional Chinese medicine carrier is prepared from the following Chinese medicine raw materials in parts by weight: 25 parts of birch, 25 parts of Shishi, 25 parts of white calamus, 12 parts of natural grass , Bupleurum 25, Evodia 12, August Zha 12, Curcuma 12, Sappan 8, Xu Changqing 8, Atractylodes 12, Coptidis 12, Citrus aurantium 12.

[0040] The preparation method of the contrast agent is as follows:

[0041] (1) Take the above-mentioned traditional Chinese medicine raw materials and pulverize them by weight, pass through a 60-mesh sieve, add distilled water with 4 to 8 times the mass of the mixed traditional ...

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Abstract

The invention belongs to the technical field of traditional Chinese medicines and particularly relates to a contrast medium applicable to the liver depression and spleen vacuity type irritable bowel syndrome. The contrast medium comprises liposome and microvesicles coated with the liposome, wherein the liposome is prepared from components in parts by weight as follows: 10-25 parts of lecithin and 45-70 parts of traditional Chinese medicine carriers; the contrast medium is characterized in that the traditional Chinese medicine carriers are prepared from traditional Chinese medicine raw materials in parts by weight as follows: 20-30 parts of Grewia biloba, 20-30 parts of sieve sedge, 20-30 parts of sweetflag root, 10-15 parts of roots of root of small diuranthera, 20-30 parts of Chinese thorowax roots, 10-15 parts of medicinal evodia fruits, 10-15 parts of akebia fruits, 10-15 parts of turmeric root tubers, 5-10 parts of sappan wood, 5-10 parts of paniculater swallowwort roots, 10-15 parts of atractylodes rhizomes, 10-15 parts of rhizoma coptidis and 10-15 parts of immature orange fruits. The contrast medium has the advantages of capability of inhibiting excessively rapid gastrointestinal peristalsis and nourishing gastrointestinal tracts.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine and relates to a gastrointestinal tract contrast agent, in particular to a contrast agent suitable for irritable bowel syndrome of liver depression and spleen deficiency type. Background technique [0002] The gastrointestinal tract is a hollow viscera, often affected by gas, and it is difficult to obtain satisfactory sonograms from the surface of the body by ultrasound. The diagnosis of gastrointestinal diseases often relies on gastroscopy and x-ray barium meal examination. In recent years, due to the development and application of gastrointestinal contrast-enhanced ultrasound and endoscopic ultrasonography, the scope of diagnosis of gastrointestinal diseases has been broadened. Ultrasound examination can clearly show the hierarchical structure of the gastrointestinal wall, find the location, size and shape of the tumor in the gastrointestinal wall, estimate the extent of the...

Claims

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Application Information

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IPC IPC(8): A61K49/22A61K9/127A61K36/9066A61P1/00
CPCA61K36/185A61K36/233A61K36/27A61K36/284A61K36/48A61K36/718A61K36/752A61K36/754A61K36/888A61K36/89A61K36/896A61K36/9066A61K49/223A61K49/227A61K2236/331A61K2236/333A61K2236/39A61K2300/00
Inventor 江瑞平刘从帅乔琳
Owner 江瑞平
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