Pharmaceutical preparation for treating recurrent spontaneous abortion caused by blocking antibody deficiency

Abstract

The invention belongs to the technical field of traditional Chinese medicine and relates to a pharmaceutical preparation for treating recurrent spontaneous abortion caused by blocking antibody deficiency and a preparing method thereof. The pharmaceutical preparation is prepared from melastoma dodecandrum fruit, radix acanthopanacis semticosi, radix rehmanniae praeparata, rhizoma cibotii, herba taxilli, root of Yunnan madder, herba leonuri, root of broadleaf sedge, rhizoma dioscoreae and root of long pepper. Through interaction and complementation of the medicinal materials, the functions of warming and invigorating kidney yang, warming middle and tonifying spleen, benefiting qi for activating blood circulation and clearing and activating the channels and collaterals are realized. The pharmaceutical preparation is developed specially for treating recurrent spontaneous abortion and kidney-yang deficiency caused by blocking antibody deficiency and has a remarkable effect.

Description

technical field

[0001] The invention belongs to the technical field of traditional Chinese medicine, and relates to a pharmaceutical preparation for treating recurrent miscarriage caused by insufficient blocking antibodies and a preparation method thereof. Background technique

[0002] Recurrent spontaneous abortion (RSA) is a common pregnancy complication, which refers to the spontaneous abortion of two or more fetuses with the same spouse before 28 weeks of pregnancy. The etiology and pathogenesis of this disease are quite complicated, and it is also a difficult disease of worldwide common concern. About half of RSV is related to immunity. Among the immune indicators, blocking antibody (BA) is considered to be the most valuable. The research on blocking antibody and recurrent miscarriage has become one of the hot spots in the research of this disease. Insufficient or negative blocking antibody will lead to paternal antigen being absorbed by the mother. The immune system r...

Examples

Embodiment 1

[0029] Embodiment 1 capsule

[0030] Prescription: 25 parts of Dixie fruit, 15 parts of Acanthopanax, 12 parts of Rehmannia glutinosa, 10 parts of Gouji, 6 parts of Sangjisheng, 10 parts of small red ginseng, 8 parts of Motherwort, 12 parts of Cliff palm root, 25 parts of Chinese yam, Piper 8 parts of longan root.

[0031] Preparation method: mix the ground smilax fruit, Acanthopanax, Rehmannia glutinosa, dog ridge, mulberry, red ginseng, motherwort, twig root, Chinese yam, and longicillium root according to the prescription ratio, and add 4 ~ 10 times the amount of water, decocted for 2-3 hours, filtered to obtain the first extract; the dregs obtained by filtering were added with water 3-7 times the mass of the dregs, decocted for 1-2 hours, filtered to obtain the second extract. Two extracts: combine the first extract and the second extract, concentrate under reduced pressure, and dry to obtain a dry paste, place the paste in an ultrafine pulverizer for 1 to 2 hours, crush,...

Embodiment 2

[0032] Embodiment 2 capsules

[0033] Prescription: 20 parts of Dixie fruit, 15 parts of Acanthopanax, 10 parts of Rehmannia glutinosa, 8 parts of Gouji, 6 parts of Sangjisheng, 15 parts of small red ginseng, 10 parts of Motherwort, 8 parts of Cliff palm root, 20 parts of Chinese yam, Piper 6 parts of onion root.

[0034] Preparation method: carry out with reference to Example 1.

Embodiment 3

[0035] Embodiment 3 capsules

[0036] Prescription: 25 parts of Dixie fruit, 18 parts of Acanthopanax, 15 parts of Rehmannia glutinosa, 12 parts of Gouji, 5 parts of Sangjisheng, 12 parts of small red ginseng, 8 parts of Motherwort, 8 parts of Cliff palm root, 20 parts of Chinese yam, Piper 5 parts of longan root.

[0037] Preparation method: carry out with reference to Example 1.

technical field

[0001] The invention belongs to the technical field of traditional Chinese medicine, and relates to a pharmaceutical preparation for treating recurrent miscarriage caused by insufficient blocking antibodies and a preparation method thereof. Background technique

[0002] Recurrent spontaneous abortion (RSA) is a common pregnancy complication, which refers to the spontaneous abortion of two or more fetuses with the same spouse before 28 weeks of pregnancy. The etiology and pathogenesis of this disease are quite complicated, and it is also a difficult disease of worldwide common concern. About half of RSV is related to immunity. Among the immune indicators, blocking antibody (BA) is considered to be the most valuable. The research on blocking antibody and recurrent miscarriage has become one of the hot spots in the research of this disease. Insufficient or negative blocking antibody will lead to paternal antigen being absorbed by the mother. The immune system r...

Examples

Embodiment 1

[0029] Embodiment 1 capsule

[0030] Prescription: 25 parts of Dixie fruit, 15 parts of Acanthopanax, 12 parts of Rehmannia glutinosa, 10 parts of Gouji, 6 parts of Sangjisheng, 10 parts of small red ginseng, 8 parts of Motherwort, 12 parts of Cliff palm root, 25 parts of Chinese yam, Piper 8 parts of longan root.

[0031] Preparation method: mix the ground smilax fruit, Acanthopanax, Rehmannia glutinosa, dog ridge, mulberry, red ginseng, motherwort, twig root, Chinese yam, and longicillium root according to the prescription ratio, and add 4 ~ 10 times the amount of water, decocted for 2-3 hours, filtered to obtain the first extract; the dregs obtained by filtering were added with water 3-7 times the mass of the dregs, decocted for 1-2 hours, filtered to obtain the second extract. Two extracts: combine the first extract and the second extract, concentrate under reduced pressure, and dry to obtain a dry paste, place the paste in an ultrafine pulverizer for 1 to 2 hours, crush,...

Embodiment 2

[0032] Embodiment 2 capsules

[0033] Prescription: 20 parts of Dixie fruit, 15 parts of Acanthopanax, 10 parts of Rehmannia glutinosa, 8 parts of Gouji, 6 parts of Sangjisheng, 15 parts of small red ginseng, 10 parts of Motherwort, 8 parts of Cliff palm root, 20 parts of Chinese yam, Piper 6 parts of onion root.

[0034] Preparation method: carry out with reference to Example 1.

Embodiment 3

[0035] Embodiment 3 capsules

[0036] Prescription: 25 parts of Dixie fruit, 18 parts of Acanthopanax, 15 parts of Rehmannia glutinosa, 12 parts of Gouji, 5 parts of Sangjisheng, 12 parts of small red ginseng, 8 parts of Motherwort, 8 parts of Cliff palm root, 20 parts of Chinese yam, Piper 5 parts of longan root.

[0037] Preparation method: carry out with reference to Example 1.

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