Novel application of notoginseng in preparation of medicine for treating and/or preventing prostatitis

A technology for prostatitis and new uses, applied to the new use of Panax notoginseng saponins, and the field of preparation of drugs for the treatment and/or prevention of prostatitis, which can solve the problems of not finding Panax notoginseng, Panax notoginseng extracts or Panax notoginseng saponins, etc. , to achieve the effect of preventing non-bacterial prostatitis, significant therapeutic effect, and simple preparation process

Inactive Publication Date: 2016-06-15
GUANGXI WUZHOU PHARMA GRP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] At present, there are no literature reports related to the use of Panax notoginseng, Panax notoginseng extract or total saponins of Panax notoginseng for the treatment of prostatitis

Method used

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  • Novel application of notoginseng in preparation of medicine for treating and/or preventing prostatitis
  • Novel application of notoginseng in preparation of medicine for treating and/or preventing prostatitis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0041] Example 1: Preparation of Radix Notoginseng Extract

[0042] Take 2kg Panax notoginseng, crush it, add 20 times of 65% ethanol, ultrasonically extract twice, each extraction time is 30min, filter, and combine the extracts; add 5 times of 75% ethanol to the dregs, soak at 55°C for 0.5h, filter , mixed with the above obtained extract, concentrated and dried to obtain the notoginseng extract.

[0043] Taking ginsenoside Rg3 as a control, the absorbance was measured, and calculated according to the regression equation, the extraction rate of total saponins in Panax notoginseng was 12.67%.

Embodiment 2

[0044] Embodiment 2: the preparation of Panax notoginseng extract

[0045] Take 2kg Panax notoginseng, crush it, add 30 times of 40% ethanol, ultrasonically extract twice, each extraction time is 60min, filter, and combine the extracts; add 15 times of 75% ethanol to the dregs, soak at 60°C for 5h, filter, Mix with the extract obtained above, concentrate, and dry to obtain the extract of Panax notoginseng.

[0046] Using ginsenoside Rg3 as a control, the absorbance was measured. According to the regression equation, the extraction rate of total saponins in Panax notoginseng was 13.46%.

Embodiment 3

[0047] Embodiment 3: the preparation of Panax notoginseng extract

[0048] Take 2kg Panax notoginseng, crush it, add 40 times of 70% ethanol, ultrasonically extract 3 times, each extraction time is 90min, filter, and combine the extracts; add 10 times of 95% ethanol to the dregs, soak at 70°C for 8h, filter, Mix with the extract obtained above, concentrate, and dry to obtain the extract of Panax notoginseng.

[0049] Using ginsenoside Rg3 as a control, the absorbance was measured. According to the regression equation, the extraction rate of total saponins in Panax notoginseng was 13.05%.

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Abstract

The invention relates to novel application of notoginseng, in particular to novel application of panax notoginseng saponins in preparation of medicine for treating and / or preventing prostatitis. The ginsenoside Rg3 content in the panax notoginseng saponins is not less than 25%, an experiment proves that the ginsenoside Rg3 has the remarkable effect of treating the prostatitis and is quick in effect and small in side effect, a preparation process is simple, and the problem that the prostatitis treating effects of western medicines are not ideal and lots of side effects are brought is solved.

Description

technical field [0001] The present invention relates to the new application of Panax notoginseng and its extract, especially the new application of Panax notoginseng saponins, that is, the new application in the preparation of medicines for treating and / or preventing prostatitis Background technique [0002] Prostatitis syndrome (ProstatitisSysndrome, PS) is a universally recognized medical chronic disease, known as "an incurable disease that is not cancer". PS is a common disease of the male urinary system, mainly in middle-aged and elderly men, and it is on the rise and younger. It has become a common and frequently-occurring disease that threatens men's health. Prostate diseases are mainly prostatitis and benign prostatic hyperplasia, which are clinically manifested as dysuria, discomfort during urination, dysuria, and decreased sexual function. Clinically, prostatitis is divided into 4 categories: ①acute bacterial prostatitis (ABP); ②chronic bacterial prostatitis (CBP);...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/258A61P13/08
CPCA61K36/258A61K2236/333A61K2236/39A61K2236/55
Inventor 谭喜梅林艳英邓裕彦黄源春郑志远杨北妮
Owner GUANGXI WUZHOU PHARMA GRP
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