Serum microRNA liver cancer diagnostic markers and kits

A diagnostic kit, hsa-mir-192 technology, applied in the field of biomedicine, can solve the problems of inability to comprehensively and objectively reflect circulating microRNA, difficult to explain marker diagnostic markers, lack of multi-center verification, etc., to save time and labor costs , avoid the complicated detection in the past, and obtain the effect easily
CN105671178BActive Publication Date: 2019-12-03江苏阔然生物医药科技有限公司
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
江苏阔然生物医药科技有限公司
Publication Date
2019-12-03

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Abstract

The invention discloses a hepatocellular carcinoma diagnosis marker combination composed of serum microRNA and a kit comprising the marker combination. The hepatocellular carcinoma diagnosis marker combination comprises following microRNA: has-miR-145, hsa-miR-29a, hsa-miR-29c, hsa-miR-133a, hsa-miR-192 and hsa-miR-505. The hepatocellular carcinoma diagnosis marker combination and the kit can be used for liver cancer diagnosis.
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Description

technical field

[0001] The invention belongs to the field of biomedical diagnosis, and in particular relates to a liver cancer diagnostic combination composed of serum microRNA, said serum microRNA including hsa-miR-145, hsa-miR-29a, hsa-miR-29c, hsa-miR-133a, hsa -miR-192 and hsa-miR-505, and a kit for the diagnosis of liver cancer and its application. Background technique

[0002] Primary liver cancer is a common malignant tumor with high morbidity and mortality worldwide, among which hepatocellular carcinoma (referred to as liver cancer, Hepatocellular Carcinoma, HCC) accounts for more than 90% of primary liver cancer. According to the "Global Cancer Report 2014" issued by the World Health Organization, in 2012, the new cases of liver cancer in the world ranked fifth among malignant tumors, and its fatality rate ranked second. Among them, the new cases and deaths of liver cancer in China were about accounted for half of the global cases. Due to the lack of effective scr...

Claims

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