Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

BDZL (bendazac lysine) eye drops

A technology of benzyl lysine and eye drops, which is applied in the field of pharmaceutical preparations, can solve the problems of patients being unbearable, affecting the curative effect, and large irritation, and achieve the effects of improved bioavailability, stable therapeutic effect, and quick effect

Inactive Publication Date: 2016-06-22
GUANGDONG YIMING PHARMA
View PDF5 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The biggest disadvantage of the listed benzyl lysine eye drops is: strong irritation, local irritation including burning sensation and red eyes, pain and tearing after use, which is unbearable for patients, and tears It will take away the medicine and affect the curative effect

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • BDZL (bendazac lysine) eye drops
  • BDZL (bendazac lysine) eye drops
  • BDZL (bendazac lysine) eye drops

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0026] The following specific examples illustrate the present invention in detail.

[0027] Embodiment and comparative example are shown in the following table 1:

[0028] Table 1: (unit: part)

[0029]

[0030] (1) According to the "Technical Guidelines for Stability Research of Chemical Drugs", the accelerated test is carried out. Test sample 1 (sample 1 was prepared according to the ratio of Example 3) was subjected to an accelerated test for 6 months under the conditions of 40°C±2°C and RH20%±5%. , 6-month sampling inspection indicators.

[0031] Table 2: Accelerated test results

[0032]

[0033] Conclusion: The detection results of the accelerated test show that the quality of the Bendalysine eye drops prepared in Example 3 of the present invention is stable.

[0034] (2) Comparison of the irritation of Bendalysine Eye Drops with the same type of products on the market

[0035] Validation design: A total of 10 healthy volunteers were used to compare the left a...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to the technical field of pharmaceutical preparations, in particular to BDZL (bendazac lysine) eye drops. The BDZL eye drops are used for preventing and treating senile cataract and are prepared from components in parts by mass as follows: 2-3 parts of BDZL, 0.02-0.03 parts of polysorbate-60, 0.01-0.02 parts of polysorbate-20, 0.15-0.25 parts of benzalkonium chloride, 2-2.5 parts of monosodium phosphate, 6-6.5 parts of sodium hydrogen phosphate, 0.1-0.15 parts of methyl 4-hydroxybenzoate, 0.05-0.15 parts of C25H25O6N2Zn and up to 1,000 parts of water for injection. The BDZL eye drops have the advantages that the quality is stable, irritation for eyes is remarkably lower than that of like products sold in the market, the bioavailability is improved remarkably by means of the effective component BDZL under matching of C25H25O6N2Zn, the absorption is good, the effect is taken rapidly, and the treatment effect is stable.

Description

technical field [0001] The invention relates to the technical field of pharmaceutical preparations, in particular to a Bendax lysine eye drop, which is used for preventing and treating cataract. Background technique [0002] Cataract is caused by various reasons such as aging, genetics, local nutritional disorders, immune and metabolic abnormalities, trauma, poisoning, radiation, etc., which can cause lens metabolic disorders, resulting in lens protein denaturation and turbidity. At this time, the light is blocked by the turbid lens. Projected on the retina, objects cannot be seen clearly. From the perspective of preventing and treating blindness in groups, the World Health Organization degeneration and opacity of the lens becomes opaque, so as to affect vision, and those whose corrected vision is 0.7 or below are included in the scope of cataract diagnosis. Cataract (senile cataract) is one of the most common eye diseases and is the number one cause of blindness in the wor...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K9/08A61K31/416A61K47/22A61P27/12
CPCA61K9/08A61K9/0048A61K31/416A61K47/22
Inventor 李易春
Owner GUANGDONG YIMING PHARMA
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com