Scar-repairing silica gel containing human-like collagen

A human-like collagen and silicone gel technology, applied in medical science, bandages, etc., can solve the problem of not paying attention to the transdermal absorption rate of collagen, and achieve the effect of accelerating the transdermal absorption rate and improving the transdermal absorption rate.

Active Publication Date: 2016-06-29
SHAANXI GIANT BIOTECHNOLOGY CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Unfortunately, the studies so far have only focused on the transdermal absorption rate of collagen, but not on the transdermal absorption rate of collagen.

Method used

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  • Scar-repairing silica gel containing human-like collagen
  • Scar-repairing silica gel containing human-like collagen
  • Scar-repairing silica gel containing human-like collagen

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preparation example Construction

[0029] There is no special limitation on the preparation method of the human collagen silica gel of the present invention, and the usual preparation method may include:

[0030] Step A: preparing phase A, the phase A is composed of 2-5% by weight of silicon dioxide, 30-50% by weight of cyclopentasiloxane, and the rest of polydimethylsiloxane;

[0031] Step B: preparing phase B, the phase B is human-like collagen liquid, which contains human-like collagen such that the content of human-like collagen in the human-like collagen silicon gel is 0.01-0.1% by weight, The medium is water such that the water content in the human-like collagen silica gel is 0.05% to 1% by weight;

[0032] Step C: preparing phase C, the phase C is 1-10% by weight of polydimethylsiloxanol; and

[0033] Step D: Then, use the phase C to disperse the phase B and then add it to the phase A, and stir evenly;

[0034] The total weight of the human collagen-like silica gel is taken as 100% by weight.

[0035]...

Embodiment 1

[0045] Embodiment 1. Preparation of human-like collagen silica gel of the present invention

[0046] Ingredients: Silica 3%, Dimethicone 51.45%, Cyclopentasiloxane 40%, Human Collagen 0.05%, Dimethiconol 5%, Water 0.5%.

[0047] Process operation:

[0048] ① Add silicon dioxide first, then slowly add polydimethylsiloxane, and keep stirring until uniform after adding. Then add cyclopentasiloxane, stir while adding, and keep stirring after the addition until the silicon dioxide is completely dispersed;

[0049] ②Dissolve human-like collagen in water to obtain human-like collagen solution, disperse human-like collagen solution in polydimethylsiloxanol, add silicon dioxide, cyclopentasiloxane and silicon dioxide In the mixing system, keep stirring until uniform.

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Abstract

The invention relates to the field of medical/cosmetic apparatuses, and in particular relates to scar-repairing silica gel containing human-like collagen, wherein the rapid transdermal absorption of the human-like collagen can be promoted. The scar-repairing silica gel can be used for repairing hyperplastic scars or keloids caused by burns, scalds, trauma, operations and the like in the medical/cosmetic field. The scar-repairing silica gel contains the human-like collagen, silica, cyclopentasiloxane, dimethiconol, water and polydimethylsiloxane.

Description

technical field [0001] The invention relates to a human-like collagen dressing, in particular to a scar repair silicone gel containing human-like collagen, and belongs to the field of cosmetic / medical equipment. Background technique [0002] Human-like collagen was invented by Professor Fan Daidi of Northwest University in China (see Chinese Patent Application Publication CN1371919A), so it is also called Fan's Human-like Collagen or Fan's Human-like Collagen (FHLC). Human-like collagen has a three-chain, triple-helix structure, and is a highly biocompatible recombinant collagen, which is currently widely used in medical or cosmetic fields. [0003] On the other hand, when collagen dressing products are used for example to eliminate hypertrophic scars or keloids caused by burns, scalds, trauma and surgery, the use of collagen dressing products often needs to be carried out indoors (such as beauty salons, hospitals, etc.) ), as a product user hopes to be able to use it in a ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L26/00
CPCA61L26/0004A61L26/0019A61L26/0033A61L26/0066A61L2300/252A61L2300/412C08L83/04
Inventor 范代娣马晓轩严建亚王淑英常海燕王小军杨婵媛
Owner SHAANXI GIANT BIOTECHNOLOGY CO LTD
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