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Medicinal composition for treating psoriasis

A composition and technology for psoriasis, applied in drug combination, drug delivery, skin diseases, etc., to achieve better effect, treat psoriasis, and simple preparation method

Active Publication Date: 2016-07-20
ZHEJIANG AEGIS BIOLOGICAL SCI & TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0031] At present, the combination of lysozyme and emodin for the prevention and treatment of psoriasis has not been reported

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0046] Embodiment 1, prepare the ointment containing emodin

[0047] Weighing 10 parts by weight of emodin, 50 parts by weight of sodium carboxymethyl cellulose, 10 parts by weight of zinc oxide and 1 part by weight of disodium edetate are dispersed in 500 parts by weight of purified water, stirred evenly to obtain water phase; then weigh 50 parts by weight of vaseline, put 10 parts by weight of Tween 80 in another container, and mix to obtain an oil phase; heat the water phase and the oil phase respectively, mix them, homogenize for 10 minutes, and prepare Become ointment A1 containing emodin.

Embodiment 2

[0048] Embodiment 2, prepare the ointment containing lysozyme

[0049] Weigh 10 parts by weight of lysozyme, 50 parts by weight of sodium carboxymethylcellulose, 10 parts by weight of zinc oxide and 1 part by weight of disodium ethylenediamine tetraacetate and disperse them in 500 parts by weight of purified water, and stir to obtain water phase; then weigh 50 parts by weight of vaseline, put 10 parts by weight of Tween 80 in another container, and mix to obtain an oil phase; heat the water phase and the oil phase respectively, mix them, homogenize for 10 minutes, and prepare into ointment A2 containing lysozyme.

Embodiment 3

[0050] Embodiment 3, prepare the ointment containing lysozyme and emodin (1:1)

[0051] Weigh 5 parts by weight of lysozyme, 5 parts by weight of emodin, 50 parts by weight of sodium carboxymethylcellulose, 10 parts by weight of zinc oxide and 1 part by weight of disodium edetate dispersed in 500 parts by weight In purified water, stir evenly to obtain the water phase; then weigh 50 parts by weight of vaseline, and put 10 parts by weight of Tween 80 in another container, and mix to obtain the oil phase; heat the water phase and the oil phase respectively and mix them, After 10 minutes of qualitative transformation, the ointment A3 containing lysozyme and emodin (1:1 by weight) was made after cooling down.

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PUM

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Abstract

The invention relates to a medicinal composition for treating psoriasis. The medicinal composition comprises the active ingredients of lysozyme and rheum emodin which are in the weight ratio of (1:10)-(10:1). Compared with a common Western medicinal preparation, a lysozyme preparation of the medicinal composition is simple in preparation method and reasonable in compatibility; the two active ingredients give play to respective effects, and meanwhile, can generate a synergetic effect; the psoriasis is treated remarkably; the lysozyme and the rheum emodin are sourced naturally and are safe and non-toxic, and have no side effect; the medicinal composition does not contain a Western medicinal component, so that the medicament has no medicament resistance.

Description

technical field [0001] The invention relates to the field of pharmacy, in particular to a medicine for treating psoriasis. Background technique [0002] Psoriasis, also known as psoriasis, is a skin disease mainly characterized by scales and erythema, accompanied by certain itching. Psoriasis is non-infectious, but has a high incidence rate, long course of disease, and is easy to relapse, stubborn and difficult to cure. It has a great impact on the patient's physical health and spirit. It has the title of "undead cancer" in dermatology. [0003] The etiology of psoriasis is still unclear. Modern studies believe that it is related to factors such as genetics, infection, immunity, spirit, endocrine, trauma, diet and metabolic disorders. At present, it is believed that immune mediation is the main mechanism of occurrence. Its clinical manifestations are erythematous and scaly lesions, with erythematous papules at the beginning, the epidermis is covered with layers of silvery w...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/47A61P17/06A61K31/122
CPCA61K38/47A61K31/122C12Y302/01017A61K9/06A61K47/06A61K9/0014A61P17/06A61K2300/00
Inventor 潘宏涛卢亚萍
Owner ZHEJIANG AEGIS BIOLOGICAL SCI & TECH CO LTD
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