Chinese and western medicine composition for treating tuberculous pleuritis and preparation method and application thereof

Abstract

The invention discloses a Chinese and western medicine composition for treating tuberculous pleuritis and a preparation method and application thereof; the Chinese and western medicine composition is prepared from, by weight, 1-3 parts of artemisinin, 3-7 parts of chlorphenamine, 15-23 parts of taurine, and 11-19 parts of amoxicillin; the preparation method comprises mixing and grinding chlorphenamine and amoxicillin, adding deionized water, and stirring at 66 DEG C for 48-50 min to obtain mixture A; mixing taurine and the mixture A, stirring at 60 DEG C for 23-25 min, adding artemisinin, ultrasonically treating at 43 DEG C for 33 min, stirring at 55 DEG C until dryness, and granulating. The Chinese and western medicine composition has significant effect in treating tuberculous pleuritis, has high cure rate, short treatment time and high acting speed, is free of toxic and side effects and allergic reaction, has high cure rate and low recurrence rate, is low in manufacture cost and low in usage and is an ideal drug.

Description

technical field

[0001] The invention relates to the technical field of medicine, in particular to a traditional Chinese and western medicine composition for treating tuberculous pleurisy and its preparation method and application. Background technique

[0002] Tuberculous pleurisy is a pleural inflammation caused by Mycobacterium tuberculosis and its autolyzed products and metabolites entering the pleural cavity of ultra-sensitive organisms. Tuberculous pleurisy is the disease caused by Mycobacterium tuberculosis first invading the body. The majority of tuberculous pleurisy in my country is caused by Mycobacterium tuberculosis. Most tuberculous pleurisy is acute. The symptoms are mainly systemic poisoning symptoms of tuberculosis and local symptoms caused by pleural effusion. The symptoms of tuberculosis poisoning are mainly manifested as fever, chills, sweating, fatigue, loss of appetite, and night sweats. Local symptoms include chest pain, dry cough, and dyspnea. Ches...

Examples

Embodiment 1

[0017] In the embodiment of the present invention, a Chinese and Western medicine composition for treating tuberculous pleurisy is composed of the following raw materials in parts by weight: 1 part of artemisinin, 3 parts of chlorpheniramine, 15 parts of taurine, and 11 parts of amoxicillin .

[0018] Mix and grind chlorpheniramine and amoxicillin, add deionized water 6.2 times the mass of the two, and stir at 66° C. for 48 minutes to prepare mixture A. Mix taurine with mixture A, stir at 60°C for 23min, add artemisinin, then ultrasonicate at 43°C for 33min, ultrasonic power is 800W, then stir at 55°C until Dried and granulated to obtain the Chinese and Western medicine composition.

Embodiment 2

[0020] In the embodiment of the present invention, a Chinese and Western medicine composition for treating tuberculous pleurisy is composed of the following raw materials in parts by weight: 3 parts of artemisinin, 7 parts of chlorpheniramine, 23 parts of taurine, and 19 parts of amoxicillin .

[0021] Mix and grind chlorpheniramine and amoxicillin, add deionized water 6.2 times the mass of the two, and stir at a temperature of 66°C for 50 minutes to prepare mixture A. Mix taurine with mixture A, stir at 60°C for 25min, add artemisinin, then ultrasonicate at 43°C for 33min, ultrasonic power is 800W, then stir at 55°C until Dried and granulated to obtain the Chinese and Western medicine composition.

Embodiment 3

[0023] In the embodiment of the present invention, a Chinese and Western medicine composition for treating tuberculous pleurisy is composed of the following raw materials in parts by weight: 1.5 parts of artemisinin, 4 parts of chlorpheniramine, 17 parts of taurine, and 13 parts of amoxicillin .

[0024] Mix and grind chlorpheniramine and amoxicillin, add deionized water 6.2 times the mass of the two, and stir at a temperature of 66°C for 49 minutes to prepare mixture A. Mix taurine with mixture A, stir at 60°C for 24min, add artemisinin, then sonicate at 43°C for 33min, ultrasonic power is 800W, then stir at 55°C until Dried and granulated to obtain the Chinese and Western medicine composition.

technical field

[0001] The invention relates to the technical field of medicine, in particular to a traditional Chinese and western medicine composition for treating tuberculous pleurisy and its preparation method and application. Background technique

[0002] Tuberculous pleurisy is a pleural inflammation caused by Mycobacterium tuberculosis and its autolyzed products and metabolites entering the pleural cavity of ultra-sensitive organisms. Tuberculous pleurisy is the disease caused by Mycobacterium tuberculosis first invading the body. The majority of tuberculous pleurisy in my country is caused by Mycobacterium tuberculosis. Most tuberculous pleurisy is acute. The symptoms are mainly systemic poisoning symptoms of tuberculosis and local symptoms caused by pleural effusion. The symptoms of tuberculosis poisoning are mainly manifested as fever, chills, sweating, fatigue, loss of appetite, and night sweats. Local symptoms include chest pain, dry cough, and dyspnea. Ches...

Examples

Embodiment 1

[0017] In the embodiment of the present invention, a Chinese and Western medicine composition for treating tuberculous pleurisy is composed of the following raw materials in parts by weight: 1 part of artemisinin, 3 parts of chlorpheniramine, 15 parts of taurine, and 11 parts of amoxicillin .

[0018] Mix and grind chlorpheniramine and amoxicillin, add deionized water 6.2 times the mass of the two, and stir at 66° C. for 48 minutes to prepare mixture A. Mix taurine with mixture A, stir at 60°C for 23min, add artemisinin, then ultrasonicate at 43°C for 33min, ultrasonic power is 800W, then stir at 55°C until Dried and granulated to obtain the Chinese and Western medicine composition.

Embodiment 2

[0020] In the embodiment of the present invention, a Chinese and Western medicine composition for treating tuberculous pleurisy is composed of the following raw materials in parts by weight: 3 parts of artemisinin, 7 parts of chlorpheniramine, 23 parts of taurine, and 19 parts of amoxicillin .

[0021] Mix and grind chlorpheniramine and amoxicillin, add deionized water 6.2 times the mass of the two, and stir at a temperature of 66°C for 50 minutes to prepare mixture A. Mix taurine with mixture A, stir at 60°C for 25min, add artemisinin, then ultrasonicate at 43°C for 33min, ultrasonic power is 800W, then stir at 55°C until Dried and granulated to obtain the Chinese and Western medicine composition.

Embodiment 3

[0023] In the embodiment of the present invention, a Chinese and Western medicine composition for treating tuberculous pleurisy is composed of the following raw materials in parts by weight: 1.5 parts of artemisinin, 4 parts of chlorpheniramine, 17 parts of taurine, and 13 parts of amoxicillin .

[0024] Mix and grind chlorpheniramine and amoxicillin, add deionized water 6.2 times the mass of the two, and stir at a temperature of 66°C for 49 minutes to prepare mixture A. Mix taurine with mixture A, stir at 60°C for 24min, add artemisinin, then sonicate at 43°C for 33min, ultrasonic power is 800W, then stir at 55°C until Dried and granulated to obtain the Chinese and Western medicine composition.

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