Methods and compositions for modulating estrogen receptor mutants

A liquid crystal display panel and liquid crystal sealant technology, which is applied in chemical instruments and methods, optics, instruments, etc., can solve the problems of easy degradation of display characteristics of liquid crystal display panels, and achieve the effects of excellent display reliability and less pollution of liquid crystals

Active Publication Date: 2017-03-08
MITSUI CHEM INC
View PDF9 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Therefore, there is a problem that the display character...

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Methods and compositions for modulating estrogen receptor mutants
  • Methods and compositions for modulating estrogen receptor mutants
  • Methods and compositions for modulating estrogen receptor mutants

Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0141] Examples related to the present invention will be specifically described below, but the present invention is not limited to these Examples. Therefore, materials, production methods, and the like can be appropriately changed without departing from the present invention.

Synthetic example 1

[0142] [Synthesis Example 1] (Synthesis of methacrylic acid-modified bisphenol F-type epoxy resin (95% partial methacrylate))

[0143] Drop into 160g liquid bisphenol F type epoxy resin (Epotohto YDF-8170C Nippon Steel Sumikin Chemical Co., Ltd. manufacture epoxy equivalent 160g / eq), 0.1g p-methoxyphenol (polymerization inhibitor), 0.2g triethanolamine (catalyst), and 81.7 g of methacrylic acid. Dry air was sent into the said flask, and it was made to react at 90 degreeC, stirring for 5 hours under reflux. The resulting compound was washed 20 times with ultrapure water to obtain a methacrylic acid-modified bisphenol F-type epoxy resin (weight average molecular weight: 484).

Embodiment 1

[0145] 100 parts by mass of methacrylic acid modified bisphenol F type epoxy resin obtained in Synthesis Example 1, two (η5-2,4-cyclopentadien-1-yl)-bis(2,6-difluoro- 0.5 parts by mass of 3-(1H-pyrrol-1-yl)-phenyl)titanium (trade name Irgacure 784, manufactured by BASF Corporation) and 0.5 parts by mass of oxalic acid were mixed to prepare a liquid crystal sealing compound composition.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

PropertyMeasurementUnit
Epoxy equivalentaaaaaaaaaa
Login to view more

Abstract

Described herein are methods and compositions for treating an ER-related disease condition characterized by a mutation in the ESR1 gene by administering an estrogen receptor modulator. Also described herein are methods of treating hormone resistant-estrogen receptor (ER) positive breast cancers characterized by a mutation in the ESR1 gene by administering an estrogen receptor modulator.

Description

technical field [0001] The present invention relates to a manufacturing method of a liquid crystal display panel, a liquid crystal display panel obtained by the method, and a liquid crystal sealing agent composition. Background technique [0002] In recent years, liquid crystal display panels have been widely used as image display panels of various electronic devices typified by mobile phones and personal computers. A liquid crystal display panel is an image display panel having a structure in which a liquid crystal material (hereinafter, simply referred to as "liquid crystal") is sandwiched between two transparent substrates with electrodes provided on the surface, and its periphery is sealed with a liquid crystal sealant. [0003] Although the usage-amount of the said liquid crystal sealing compound is small, since it contacts a liquid crystal directly, it will have a big influence on the reliability of a liquid crystal display panel. Therefore, in order to realize high i...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): G02F1/1339C08F2/50C09K3/10
CPCC08F2/50C09K3/10G02F1/1339
Inventor 沟部佑司村田达司河野大辅
Owner MITSUI CHEM INC
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap