Triple oral vaccine for marine cultured fishes and preparation method thereof

Abstract

The invention discloses triple oral vaccine for marine cultured fishes and a preparation method thereof. The triple oral vaccine comprises the following formula components in parts by mass: 0.8 to 1 part of a phagostimulant, 13 to 15 parts of a saltwater fishmultivitamin, 8 to 10 parts of vitamin E, 12 to 13 parts of pharmaceutical starch, 13 to 15 parts of maltodextrin, 1 to 5 parts of vibrio harveyi, 4 to 6 parts of vibrio vulnificus, 12 to 16 parts of soyabean protein, 2 to 4 parts of vibrio parahemolyticus broth, 4 to 6 parts of edwardsiella tarda broth, 2 to 4 parts of vibrio alginolyticus, 2 to 4 parts of vibrio alginolyticus broth, and 5 to 7 parts of a multivitamin. The triple oral vaccine is ideal for immune effect, small in workload and suitable for mass vaccination campaign, meanwhile adopts a functional coating material, not only prevents the vaccine from being digested in gastric juice, but also ensures that the vaccine is rapidly released in an intestinal tract, produces immunoreactions, and obtains efficient immune effect.

Description

technical field [0001] The invention relates to the technical field of vaccine epidemic prevention for cultured seawater fish, in particular to a triple oral vaccine for cultured seawater fish and a preparation method thereof. Background technique [0002] The diseases of marine cultured fish in my country are increasing year by year, especially the prevalence of Vibrio parahaemolyticus, Vibrio alginolyticus and Edwardsiella tarda, which have caused huge economic losses and seriously hindered the development of aquaculture in my country. At present, fish bacterial diseases are mainly prevented and treated by using antibacterial drugs combined with optimized breeding techniques. However, the long-term use of antibiotics and chemicals has caused most bacteria to develop strong and extensive drug resistance, and has also caused food safety problems such as environmental pollution and excessive drug residues. Due to the problem of drug residues, the export of aquatic products i...

AI Technical Summary

Problems solved by technology

All the above researches use injection and immersion immunization methods. Because immersion has disadvantages such as poor immune effect and large amount of vaccine, the ope