Medicine composition for treating dairy cow mastitis as well as preparation method and application thereof

Abstract

The invention provides a medicine composition for treating dairy cow mastitis. The medicine composition is prepared from the following raw material medicines in parts by weight: 1 to 3 parts of periplaneta Americana and 1 to 3 parts of solidago virgaurea. The invention further provides a preparation method and the application of the medicine composition. By compatible use of the periplaneta Americana and the solidago virgaurea, the medicine composition is used for treating the dairy cow mastitis, develops the synergistic interaction, has an obvious medicinal effect, is safe to use, does not have side effect, and provides a new medicine application choice for clinical treatment.

Description

technical field

[0001] The invention relates to a pharmaceutical composition for treating cow mastitis, which belongs to the field of veterinary medicine. Background technique

[0002] Mastitis is an inflammation caused by pathogenic microorganisms infecting the mammary parenchyma, interstitium and parenchymal interstitium. It is customarily called mastitis. Mastitis in dairy cows is caused by two types of pathogenic microorganisms, one is infectious pathogenic microorganisms (also known as cattle-dependent pathogenic microorganisms) such as: Staphylococcus aureus, Streptococcus agalactiae, etc.; the other is conditional pathogenic microorganisms ( Also known as environmental pathogenic microorganisms) such as: Escherichia coli, Klebsiella, Streptococcus uberis, etc. Mastitis has two manifestations of clinical mastitis and subclinical mastitis. I clinical mastitis, the milk is thin, off-white in mild cases, with flocs, the breast pain is not obvious, the milk production d...

Examples

Embodiment 1

[0020] The preparation of embodiment 1 medicine of the present invention

[0021] Take Periplaneta americana 1000g (A), Periplaneta americana 500g: Solidago 500g (B), Solidago 1000g (C) an appropriate amount, add 30 times the amount of ethanol, decoct 2 times, 1 hour each time, filter, combine the filtrate, Concentrate to a clear paste with a relative density of 1.13-1.15 (60-70°C), add ethanol to make the final content 75%, filter the precipitate, recover the ethanol from the filtrate, add water to 500ml, let stand for 48 hours, filter, and use 10% hydrogen to filter the filtrate Adjust the pH value of the sodium oxide solution to 6.5, add water for injection to 1000ml, mix well, and then treat with activated carbon, refrigerate, filter, pot, and sterilize to obtain the product.

Embodiment 2

[0022] The preparation of embodiment 2 medicines of the present invention

[0023] Get Periplaneta americana 1000g, Solidago 3000g, prepare by embodiment 1 method.

Embodiment 3

[0024] Embodiment 3 preparation of medicine of the present invention

[0025] Get Periplaneta americana 3000g, Solidago 1000g, prepare by the method of embodiment 1.

[0026] Prove the beneficial effect of the present invention below by concrete pharmacodynamics test.

technical field

[0001] The invention relates to a pharmaceutical composition for treating cow mastitis, which belongs to the field of veterinary medicine. Background technique

[0002] Mastitis is an inflammation caused by pathogenic microorganisms infecting the mammary parenchyma, interstitium and parenchymal interstitium. It is customarily called mastitis. Mastitis in dairy cows is caused by two types of pathogenic microorganisms, one is infectious pathogenic microorganisms (also known as cattle-dependent pathogenic microorganisms) such as: Staphylococcus aureus, Streptococcus agalactiae, etc.; the other is conditional pathogenic microorganisms ( Also known as environmental pathogenic microorganisms) such as: Escherichia coli, Klebsiella, Streptococcus uberis, etc. Mastitis has two manifestations of clinical mastitis and subclinical mastitis. I clinical mastitis, the milk is thin, off-white in mild cases, with flocs, the breast pain is not obvious, the milk production d...

Examples

Embodiment 1

[0020] The preparation of embodiment 1 medicine of the present invention

[0021] Take Periplaneta americana 1000g (A), Periplaneta americana 500g: Solidago 500g (B), Solidago 1000g (C) an appropriate amount, add 30 times the amount of ethanol, decoct 2 times, 1 hour each time, filter, combine the filtrate, Concentrate to a clear paste with a relative density of 1.13-1.15 (60-70°C), add ethanol to make the final content 75%, filter the precipitate, recover the ethanol from the filtrate, add water to 500ml, let stand for 48 hours, filter, and use 10% hydrogen to filter the filtrate Adjust the pH value of the sodium oxide solution to 6.5, add water for injection to 1000ml, mix well, and then treat with activated carbon, refrigerate, filter, pot, and sterilize to obtain the product.

Embodiment 2

[0022] The preparation of embodiment 2 medicines of the present invention

[0023] Get Periplaneta americana 1000g, Solidago 3000g, prepare by embodiment 1 method.

Embodiment 3

[0024] Embodiment 3 preparation of medicine of the present invention

[0025] Get Periplaneta americana 3000g, Solidago 1000g, prepare by the method of embodiment 1.

[0026] Prove the beneficial effect of the present invention below by concrete pharmacodynamics test.

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