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Blood-glucose-reducing traditional Chinese medicine composition and preparation method thereof

A hypoglycemic and composition technology, applied in the field of hypoglycemic traditional Chinese medicine composition and preparation thereof, can solve the problems of unfavorable long-term use, complex traditional Chinese medicine formulation, heavy burden on liver and kidney, etc., achieves no toxic side effects, and controllable parameters. , the effect of correcting glucose metabolism disorders

Inactive Publication Date: 2017-10-24
BIOLOGY INST OF SHANDONG ACAD OF SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the existing traditional Chinese medicine compositions for lowering blood sugar and treating diabetes all have a certain degree of hypoglycemic effect, the traditional Chinese medicines used are complicated in prescription, large in dosage, complicated in preparation, and heavy burden on liver and kidney after long-term use, which is unfavorable for long-term use. take

Method used

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  • Blood-glucose-reducing traditional Chinese medicine composition and preparation method thereof
  • Blood-glucose-reducing traditional Chinese medicine composition and preparation method thereof
  • Blood-glucose-reducing traditional Chinese medicine composition and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] Embodiment 1. A kind of hypoglycemic traditional Chinese medicine composition, by weight, is made of the following raw materials: Polygonatum 25 parts, Radix Puerariae 25 parts, Maca 15 parts, Schisandra chinensis 10 parts, Dendrobium 5 parts, mulberry 20 parts, corn 20 copies are required.

[0032] The preparation method is: dry and pulverize Polygonatum odoratum, mulberry and corn silk at 40°C, add 10 times the amount of water to extract three times at 80°C, combine the extracts, add 0.5% (weight to volume ratio) chitin to flocculate, and obtain the first extract . Pueraria root, Maca and Schisandra were dried and pulverized at 40°C, added with 3 times the amount of water and 1.5% cellulase (weight to volume ratio), and enzymatically hydrolyzed for 30 minutes at 35°C and pH 5. After enzymatic hydrolysis, add 15 times the amount of 80% ethanol, extract 3 times at 50°C, each time for 60min, and combine the extracts. The extract was purified by D101 macroporous adsorpt...

Embodiment 2

[0033] Embodiment 2. A hypoglycemic traditional Chinese medicine composition, in parts by weight, is made of the following raw materials: 15 parts of Polygonatum Polygonatum, 15 parts of Pueraria Radix, 10 parts of Maca, 5 parts of Schisandra chinensis, 5 parts of Dendrobium, 10 parts of Mulberry, and 10 servings of corn silk.

[0034]The preparation method is as follows: dry and pulverize Polygonatum odoratum, mulberry and corn silk at 50°C, add 5 times the amount of water to extract twice at 90°C, combine the extracts, add 1% (weight to volume ratio) chitin to flocculate, and obtain the first extract . Pueraria root, Maca and Schisandra were dried and pulverized at 50°C, added with 3 times the amount of water and 1% cellulase (weight to volume ratio), and enzymatically hydrolyzed for 40 minutes at 40°C and pH value 5.5. After enzymatic hydrolysis, add 10 times the amount of 80% ethanol to extract 3 times at 60°C, each time for 70min, and combine the extracts. The extract i...

Embodiment 3

[0035] Embodiment 3. A hypoglycemic traditional Chinese medicine composition, made of the following raw materials in parts by weight: 35 parts of Polygonatum Polygonatum, 35 parts of Pueraria radiata, 20 parts of Maca, 15 parts of Schisandra chinensis, 8 parts of Dendrobium, 25 parts of mulberry, corn 25 copies are required.

[0036] The preparation method is: dry and pulverize Polygonatum odoratum, mulberry and corn silk at 60°C, add 8 times the amount of water to extract twice at 100°C, combine the extracts, add 3% (weight to volume ratio) chitin to flocculate, and obtain the first extract . Pueraria root, Maca and Schisandra were dried and pulverized at 50°C, added with 3 times the amount of water and 2% cellulase, and enzymatically hydrolyzed at 50°C and pH 6 for 60 minutes. After enzymatic hydrolysis, 13 times the amount of 80% ethanol was added to extract twice at 80°C, each time for 90 minutes, and the extracts were combined. The extract is purified by D101 macroporou...

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Abstract

The invention provides a blood-glucose-reducing traditional Chinese medicine composition and a preparation method thereof. The traditional Chinese medicine composition is produced from polygonatum odoratum, kudzu roots, Maca, schisandra chinensis, dendrobium nobile, mulberries, and corn silk. The traditional Chinese medicine composition is based on nourishing yin, tonifying Qi and removing heat-toxin, wherein synergistic effects of the raw materials are achieved, so that the composition has multidirectional, multilayer and multi-targeted clinical effects of assistant blood glucose reduction, and has excellent prevention and treatment effect on various complications caused by diabetes. The composition has low side effects, is low in cost, and is high in quality controllability during production, and is suitable for large-scale pharmaceutical production.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for lowering blood sugar and a preparation method thereof, belonging to the technical field of medicine. Background technique [0002] Diabetes is a chronic lifelong disease with high prevalence. According to WHO statistics, there were more than 170 million diabetics worldwide in 2000, and it is expected to exceed 360 million in 2030. There are more than 40 million diabetic patients in my country, accounting for 20% of the total number of diabetic patients in the world. [0003] Diabetes is a metabolic syndrome caused by the loss or decline of pancreatic islet function, insulin resistance, etc. Long-term diabetes can lead to chronic damage to the nervous system, cardiovascular system, urinary system and other systems. High mortality rate and low control rate. Diabetes can be divided into type 1 and type 2 from the pathological point of view. Type 1 diabetes is the complete loss of i...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61P3/10
CPCA61K36/31A61K36/488A61K36/57A61K36/605A61K36/79A61K36/8969A61K36/8984A61K36/899A61K2236/19A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61K2300/00
Inventor 张轩铭韩利文侯海荣张姗姗李晓彬何秋霞刘可春
Owner BIOLOGY INST OF SHANDONG ACAD OF SCI
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