61 results about "Pancreatic islet function" patented technology

The invention belongs to the technical field of medicine-food homologous formula food and particularly relates to special diet for hyperglycemia patients. The reason inducing hyperglycemia is that hepatic glycogen output is increased, too much high-fat food is ingested, the pancreatic islet function can not excellently secrete insulin, and then, the blood sugar content is increased. The traditional Chinese medical science always stresses that dietotherapy is better than medication, so as to avoid injection and medication and even pain of surgery. According to the special diet, whole grains are perfectly combined with medicine-food homologous and new-resource-food traditional Chinese medicines, and diet and health preserving are organically combined so as to regulate, prevent and resist hyperglycemia; probiotics are creatively utilized as a pioneer based on the inheritance of Chinese traditional Chinese medicine treasure treatment methods, and the proliferation of the probiotics is promoted, so that the movement functions of the spleen and stomach are enhanced; and meanwhile, various natural and original ecological medicine-food homologous edible materials are added according to the physical characteristics of hyperglycemia patients, so that the special diet has the unique advantage of integrated dietotherapy, prevention and regulation effects.

The invention provides an improved flour food. The improved flour comprises dietary fiber, whole wheat flour dietary fiber and amylose extracted from corn, potato, sweet potato and rice; the flour can be made into fine dried noodles, dumplings, gruel, bread, pastry, cake, steamed bread and so on. The food has low glycemic index, can satisfy health and nutrition of human body, delay the sugar absorption, effectively control blood sugar in diabetes patients, make the glycolated hemoglobin restore to normal value; the food with low glycemic index can reduce load of pancreatic islet, recover pancreatic islet function, secrete insulin resistance and protect B cell; the food with low glycemic index supplies high-nutrition content natural food to diabetes patients with nutrition utilization obstacle and nutrition deficiency caused by metabolic disorder; the invention is a kind of convenient health food.

The invention relates to a biscuit with the function of curing the diabetes and a preparation method thereof. The preparation method of the biscuit comprises the steps of: taking fingered citron, Chinese yam, mulberry, medlar, semen coicis, sealwort, fructus citri and kudzu root as raw materials; mixing the components of the raw materials; decocting extracting solution by means of water adding, and respectively filtering by a sieve with 160-180 meshes; concentrating filter liquor to obtain extractum; modulating flourdough according to the weight ratio of the extractum to the flour at 1:8-15; and preparing the biscuit by an existing normal biscuit preparation process. After the biscuit is eaten, the pancreas islet cell can be nourished, the pancreas islet function can be improved, the glucogenic index of the food can be effectively controlled, the fasting blood-glucose and the postmeal glucose can be reduced, the use level of the drug for curing the diabetes can be reduced, and the life quality can be improved.

The invention provides green tea with the function of reducing blood sugar. The green tea is prepared from the following components in parts by weight: 10-20 parts of buckwheat, 10-20 parts of agar, 5-15 parts of black fungus, 5-15 parts of bitter gourd, 5-15 parts of Chinese yam, 5-15 parts of green tea, 5-15 parts of honey and the balance of water and also comprises 106-109cfu/ml of probiotics. The invention also provides a preparation method of the green tea. The green tea is rich in nutrition and widespread in raw materials, combines various drugs, has the function of reducing blood sugar if being used for long term, is scientific in compatibility and has the effects of protecting pancreatic islet functions, improving glycometabolism and reducing sugar absorption, thus having an obvious effect of reducing blood sugar.

The kudzu vine root preparation for treating diabetes features that the kudzu vine root preparation is compounded with kudzu vine root and one or several kinds of Chinese medicinal materials of Chinese yam, tuckahoe, lophatherum herb, coix seed, etc. All the materials are medicated food materials, so that the medicine may be taken regularly. The kudzu vine root preparation can regulate body's Yin-Yang balance effectively, so as to restore the body's pancreatic islet function gradually, control and treat various complications effectively, and make the patient get rid of dependence on medicine, and has no side effect.

The invention relates to a beverage, and particularly relates to a beverage containing a fresh ginseng juice. The beverage is prepared by squeezing fresh ginseng with addition of water and is sterilized by an ultrahigh pressure device. In vivo animal experiments show that the fresh ginseng juice can significantly reduce fasting blood glucose of 2-type diabetes, increase the fasting insulin level and improve the islet function.

The invention is cDNA, cloning and expression of Chinese cobra neural growth factor (NGF), relating to cDNA and cloning of recombinant Chinese cobra neural growth factor, expression of neural growth factor, a method of using its expression carrier to prepare it and pharmacological use of the mentioned protein, separate-extracting total RNA from the poison gland of Chinese cobra, using RT-PCR method to make reverse transcription to get total cDNA, using the primer designed by us to provide a specific Cdna sequence at a length of 348 bp polynucleotide sequence and also providing a small-molecular weight protein, the molecular weight about 13000, successfully expressed in pichia pastoris. The recombinant neutral growth factor has pharmaceutical use in the aspects of reducing blood sugar and improving pancreas islet as well as curing peripheral polyneuritis caused by diabetes.

The invention belongs to the technical field of strain preparation, and discloses a bifidobacterium animalis and a preparation method thereof. The preservation number of the bifidobacterium animalis is CGMCC No:12944. The bifidobacterium animalis NMC disclosed by the invention is separated from the intestinal tract of a healthy 100-year-old person, the strain has extremely high acid resistance, capable of resisting gastric acid to successfully arrive at the intestinal tract, and an intestinal tract experiment proves that the strain has the probiotic functions of significantly alleviating constipation, improving intestinal flora, alleviating ulcerative colitis, enhancing the pancreatic islet function and fat metabolism of animals with type II diabetes, decreasing the triglyceride and cholesterol level in blood and the like, so the strain is an excellent probiotic strain; and the bifidobacterium animalis can treat constipation, prevent and treat tumors, protect the liver, treat cardiovascular disease, improve lactose digestion and delay senescence.

The invention discloses a preparation method of traditional Chinese medicinal pills for treating diabetes. The preparation method sequentially comprises the following steps: preparing materials, extracting, condensing, collecting a paste, coarsely grinding, sterilizing, mixing paste powder, drying the paste powder, grinding the dry paste, totally mixing, preparing a soft material, refining, preparing pills, flattening, drying plain pills, screening pills, coating and polishing, drying the coated pills and selecting the pills. The traditional Chinese medicinal pills are prepared from the following raw materials in parts by weight: 17-23 parts of rehmannia, 12-18 parts of radix ophiopogonis, 4-6 parts of fruit of Chinese magnoliavine, 19-23 parts of pachyrhizua angulatus, 15-19 parts of root of Chinese trichosanthes and 5-7 parts of liquorice. The preparation method disclosed by the invention is convenient to operate, and is capable of reducing labor intensity of operators and increasing yield; the preparation method is convenient for continuous and mass production; the traditional Chinese medicinal pills prepared by the method have the functions of nourishing yin, promoting fluid, quenching thirst, relieving restlessness, and benefiting and strengthening qi, and are applicable to treating material and carbohydrate metabolic disorders caused by pancreatic function decrease, diabetes caused by increase in blood sugar, deficiency in lung, stomach, kidney and yin, and later period of fever.

The invention discloses a traditional Chinese medicine preparation for reducing glucose and removing thirst, which is prepared by the thirteen raw materials of rehmannia, dogwood, yam, peony bark, and the like. A method for preparing the traditional Chinese medicine comprises the following steps: crashing seven materials of the rehmannia, the dogwood, and the like into medicinal powders for standby usage, dipping, decocting and boiling, filtering, concentrating and extracting oriental water plantain rhizome, Mongolian snakegourd root, cherokee rose fruit and other components to form medicinal active substances, concentrating the filtrate into extract with the relative density of 1.30-1.32 at 80-90 DEG C; adding the extract into the fine powders and evenly mixing to obtain the finished product. By observing the stability of three batches of glucose-reducing and thirst-removing capsules of the invention for 24 months, a result shows that all indexes are all accordant with the specifications. A pharmacodynamic experimental result shows that the product has the functions of reducing glucose and improving immunity to hyperglycemia animals with damaged insulin and cells, recovers the pancreatic island function, is suitable for clinically curing II type nondependent diabetic patients, and is safe, nontoxic and remarkable in curative effect.

The invention discloses health preserving tea lowering high blood fat, blood pressure and blood sugar The health preserving tea is mainly prepared from the following components, by weight, 60-70 parts of guava leaves, 5-8 parts of pine peel, 5-8 parts of pine needle, 7-12 parts of haw and 8-15 parts of turmeric. The health preserving tea has advantages of adjusting blood fat, softening blood vessels, dredging channels and collaterals, lowering blood fat, lowering blood pressure, lowering blood sugar, moistening intestines, relaxing bowel, raising the insulin sensitivity, repairing the damaged islet function, removing vivotoxin, eliminating fatigue, helping sleep, raising the immunity and delaying aging.

The invention discloses a functional food for adjusting blood glucose balance. The functional food is prepared from the following raw materials in parts by mass: 30-50 parts of mulberry leaf extract, 30-50 parts of cinnamomum cassia extract, 5-10 parts of vitamin C and 5-10 parts of vitamin E. Proven by experiments, not only do the raw materials in the function food have respective functions, after the raw materials are mixed together to prepare the functional food, but also the functional food is capable of adjusting the pancreatic islet function well, assisting insulin secretion in a human body to achieve a balance, adjusting glucose metabolism, also reducing blood fat at the same time and preventing blood vessels from atherosclerosis, so that the functions of adjusting blood glucose balance and preventing complications can be achieved well.

The invention discloses nutritional liquid food for promoting diabetes recovery and a preparation method thereof. Soybean protein powder and maltodextrin are dried and then pass through a 180-240-mesh sieve; soybean oligopeptide powder, maltodextrin, soybean protein powder, cranberry extracts, sea horse extracts, cactus extracts, synthetic nutrients and casein are weighed, purified water is added and mixed with the materials, and magnetic force is adopted for uniform stirring; olive oil, an emulsifier and a stabilizer are sequentially added to the uniformly-stirred materials, and homogenizing is conducted for 3-5 min; after homogenizing, reduced pressure drying sterilization is conducted, powder is obtained and packaged according to the specification of 45 g/bag, 170 ml of warm water at the temperature of 60 DEG C is added per 45 g of powder, and 200-ml nutrient supplementing or daily meal-replacing nutritional liquid food is prepared. The liquid food is suitable for patients suffering from diabetes or emergency diabetes, the bioavailability is high, free radicals can be eliminated, the immunity of organisms can be improved, the absorption effect is good, water-soluble dietary fibers and non-water-soluble dietary fibers are matched scientifically, blood sugar absorption is delayed, postprandial blood sugar is stabilized, pancreatic islet function recovery is promoted, and sugar tolerance of the organisms is improved.

The invention relates to a Chinese medicinal preparation for correcting pancreas islet function, and belongs to the technical field of Chinese medicine and Chinese medicaments. The Chinese medicinal preparation is prepared form prepared rehmannia, glossy privet fruit, chrysanthemum, cinnamon, honeysuckle, scurfpea fruit, gyp, cistanche, alpinia oxyphylla, spina date seed, rhizoma atractylodis, tortoise shell, kudzuvine root, cape jasmine, platycodon grandiflorum, amber, asparagus fern, calamus, schisandra chinensis, tribulusterrestris, lily, crude dragon bone, straight ladybell root, Chinese angelica root and white peony root. The preparation can be used for regulating vital energy of imbalanced internal organ, yin-yang and five elements of a diabetic patient, correcting control of cortical centre to the pancreas islet, so that the pancreas islet can work according to normal requirement of a human, and diabetes mellitus can be fundamentally cured. The Chinese medicinal preparation is strict in composition, excellent in drug selection and convenient to take, and does not have toxic or side effect.

The invention belongs to the field of biomedicine, and mainly relates to an application of a growth hormone releasing hormone receptor stimulant MR-409 in preparation of a drug for treating non-alcoholic fatty liver disease (NAFLD). At present, no targeted drug is provided for treatment of NAFLD, and lipid-lowering drugs and liver-protecting drugs are commonly adopted. MR-409 is novel GHRHR-A, GHRHR is widely expressed in the liver and pancreas, and literature reports that GHRHR-A has the effects of improving the pancreatic function, promoting the survival of transplanted pancreatic islets andrelieving diabetic eye complications. According to the invention, research finds that MR409 can improve non-alcoholic fatty liver disease imageology, serum enzymology, serum metabolism and histologyindexes of diabetic mice, and is expected to become a therapeutic drug for non-alcoholic fatty liver diseases. The invention provides a new application of MR-409 in treating the non-alcoholic fatty liver disease, provides a new strategy for treating the non-alcoholic fatty liver disease, has important clinical treatment significance, and provides a scientific basis for developing the MR-409 into amedicine for treating the non-alcoholic fatty liver disease in the future.

The invention relates to a compound islet function repairing hyperglycemic capsule. The formula comprises: 5% of red ginseng, 6% of astragalus, 3% of ganoderma lucidum, 3% of Schisandra chinensis, 6% of kudzu vine root, 6% of Salvia Miltiorrhiza, 4% of Ligusticum wallichii, 2% of Monopterus albus, 3% of semen cuscutae, 1% of black sesame, 7% of radix rehmanniae, 6% of prepared rhizome of rehmannia, 5% of black fungus, 2% of a ginkgo leaf extract, 3% of ophiopogon japonicus, 3% of radix asparagi, 6% of mulberry leaf, 3% of mulberry, 4% of Gynostemma pentaphyllum, 3% of pearl powder, 2% of cassia seed, 2% of coix seed, 3% of corn stigma, 3% of Coptis chinensis, 4% of bitter gourd, 4% of malt, and 1% of licorice. The preparation method includes: mixing obtained Chinese herbal mixed extract powder and mixed concentrated liquid together uniformly, putting the mixture into an infrared drying sterilization box to conduct drying and sterilization, and then loading the product into a capsule.

The invention provides a medicine for preventing/treating type 2 diabetes and an application thereof, and active ingredients in the medicine take miR-21 as a target spot and promote miR-21 in a targeted manner. In this way, the pancreas islet function can be promoted, and the purpose of reducing blood sugar is achieved.

The invention provides a traditional Chinese medicine preparation for treating diabetes, and belongs to the technical field of traditional Chinese medicines. The traditional Chinese medicine preparation for treating the diabetes is prepared from saussurea involucrata culture, radix ginseng, fructus hippophae, rhizoma polygonati odorati, rhizoma dioscoreae, white kidney bean extract, yeast beta-glucan, earthworm protein, L-arabinose, lutein ester, inulin, fructo-oligosaccharide, vitamin B1, vitamin B2, vitamin B6, vitamin B12, and isomalt. The traditional Chinese medicine preparation is strictly in accordance with the principle of ''monarch, minister, assistant and guide'' of traditional Chinese medicine, has a remarkable effect of treating the diabetes, is short in treatment period, and solves the deficiency of a current traditional Chinese medicine for treating the diabetes; and at the same time, the traditional Chinese medicine preparation provided by the invention has the effects ofstimulating pancreatic beta cells to secrete insulin, repairing islet function, increasing the sensitivity of insulin receptors, inhibiting glucose absorption, and improving fatty acid metabolism.

The invention discloses a traditional Chinese medicine composition which contains dried ginger, radix scutellariae, rhizoma coptidis, radix codonopsis, poria cocos, rhizoma atractylodis, cinnamon, radix paeoniae rubra, radix puerariae, radix et rhizoma rhei, corn stigma, gypsum, red yeast rice and stevia rebaudiana. The invention also discloses an application of the traditional Chinese medicine composition in preparation of medicines for preventing and/or treating diabetes mellitus. Monitoring of oral glucose tolerance, glycosylated hemoglobin, insulin resistance levels and pancreatic beta cell functions of diabetic patients proves that the traditional Chinese medicine composition has the treatment effects of reducing the blood sugar of the diabetic patients, improving the pancreatic function of the patients and recovering the sensitivity of organisms to insulin.

The invention relates to instant noodle with a function of treating diabetes mellitus and a preparation method thereof. The instant noodle is prepared by the following steps: step one, weighing following materials according to part by weight: 28-36 portions of bergamot, 25-30 portions of rhizoma dioscoreae, 10-13 portions of mulberry, 20-26 portions of fructus lycii, 5-7 portions of rhizoma anemarrhenae, 10-12 portions of rehmannia and 10-12 portions of radix ophiopogonis; and step two, mixing the raw materials, adding water and boiling the raw materials twice, adding 10 portions of water at the first time and boiling for two hours, adding eight portions of water and boiling for 1.5 hours, filtering extract solutions from the two times of boiling by a sieve with 160-180 meshes, concentrating filtrate until the density of the filtrate is 1.23-1.26g each cubic centimeter so as to obtain an extract, uniformly mixing the extract and wheat flour according to the proportion of the portions by weight of 1:9-12, and then preparing the instant noodle by the existing general preparing process of the instant noodle. In the invention, pancreas islet cells can be nutrient, the function of pancreas islet is improved, the sugar generation index of food can be controlled effectively, the blood sugar of limosis and the blood sugar after meal of a patient can be lowered, the taking amount of medicaments for treating the diabetes mellitus can be reduced, the life quality of the patient is improved, and the function of treating the diabetes mellitus is realized.

The invention discloses a Chinese medicinal preparation for lowering blood sugar, wherein the formula comprises ginseng 10-15 parts, astragalus root 50-80 parts, dried rehmannia root 15-20 parts, radix scrophulariae 15-20 parts, root of Chinese trichosannthes 15-25 parts, wolfberry fruit 20-30 parts, and curculigo rhizome 15-25. The invention also discloses its preparing process.

The invention discloses a preparation method and application of stem cells capable of inductively secreting insulin. At present, recombinant insulin is mainly clinically used for treating insulin-dependent diabetes mellitus. Mesenchymal stem cells are pluripotent stem cells, have all generality of stem cells, namely self-renewal and multidirectional differentiation capabilities, have a relatively strong immune regulation function, and have a treatment effect on pancreas islet function reduction caused by autoimmune injury. The induced insulin secretion type umbilical cord mesenchymal stem cell capable of responding to the change of glucose concentration has a wide application prospect in treating diabetes mellitus.