A kind of hydroxypropyl methylcellulose plant hollow capsule

A technology of hydroxypropyl methylcellulose and plant hollow capsules, which is applied in the directions of capsule delivery, pharmaceutical formulations, and medical preparations of inactive ingredients, etc., can solve problems such as hindering the development of pharmaceutical dosage forms, and achieve low loss on drying and destructive properties. Small, fast effects
CN107296801BActive Publication Date: 2020-03-17ANHUI HUANGSHAN CAPSULE CO LTD
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Patent Information

Authority / Receiving Office
CN Β· China
Patent Type
Patents(China)
Current Assignee / Owner
ANHUI HUANGSHAN CAPSULE CO LTD
Publication Date
2020-03-17

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Abstract

The invention discloses a hydroxypropyl methyl cellulose plant empty capsule which is prepared through the following method: dissolving hydroxypropyl methyl cellulose in a mixed solvent of an organic solvent and water, preparing a hydroxypropyl methyl cellulose solution with the mass percentage of 10 to 33 percent, and making capsules by using the hydroxypropyl methyl cellulose solution, wherein the organic solvent is ethyl alcohol and / or acetone. The hydroxypropyl methyl cellulose plant empty capsule has the advantages that the capsule is disintegrated fast, is not brittle and has extremely low weight loss on drying; furthermore, according to the preparation method of the capsule, no heating is needed, so that energy consumption is reduced; no gelatinizer is added, so that influence on disintegration due to the gelatinizer is avoided; the capsule is cured and molded only through volatilization of the organic solvent, so that the hydroxypropyl methyl cellulose plant empty capsule is suitable for filling of certain medicines having special requirements.
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Description

technical field

[0001] The invention relates to the technical field of auxiliary materials in pharmaceutical preparations, in particular to a hydroxypropylmethylcellulose (HPMC) plant hollow capsule. Background technique

[0002] Hollow capsules are widely used in the preparation of medicines, health care products and functional foods because of their effective isolation of drug odors and the convenience of taking them.

[0003] Most of the existing hollow capsules use animal gelatin as the main raw material, but for special drugs that require rapid disintegration and are prone to cross-linking reactions with proteins, it is not suitable to use gelatin hollow capsules for filling, and HPMC plant hollow capsules need to be used instead of gelatin Empty capsule filling. HPMC is a high molecular polymer obtained by modifying cellulose. It has good mechanical properties, chemical stability and water vapor resistance, and is a good raw material for preparing plant hollow capsule...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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