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Chinese medicine soft capsule for treating ankylosing spondylitis and preparation method thereof

A technology for ankylosing spondylitis and soft capsules, applied in the directions of capsule delivery, pharmaceutical formulations, and medical preparations containing active ingredients, etc., can solve problems such as single dosage form, achieve significant curative effect, improve drug release, and reduce unit dosage Effect

Inactive Publication Date: 2017-11-17
AFFILIATED HOSPITAL OF ZUNYI MEDICAL COLLEGE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, the formulations of Chinese patent medicines for the treatment of ankylosing spondylitis are relatively single, mainly tablets and pills

Method used

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  • Chinese medicine soft capsule for treating ankylosing spondylitis and preparation method thereof
  • Chinese medicine soft capsule for treating ankylosing spondylitis and preparation method thereof
  • Chinese medicine soft capsule for treating ankylosing spondylitis and preparation method thereof

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Effect test

Embodiment 1

[0033] An embodiment of the traditional Chinese medicine soft capsule for treating ankylosing spondylitis of the present invention, the traditional Chinese medicine soft capsule described in this embodiment includes a capsule fluid and a capsule shell, and the capsule fluid is composed of a Chinese medicine extract and a pharmaceutical auxiliary material. The mass ratio of the Chinese medicine extract to the pharmaceutical excipient is 1:1.2, and the Chinese medicine extract is composed of the following components by weight: 25 parts of Clematis clematis extract, 40 parts of Ivy vine extract, 25 parts of Rhizoma Drynariae extract parts, 10 parts of Achyranthes bidentata extract; the pharmaceutical adjuvant consists of the following components by weight: 8 parts of diluent, 7 parts of suspending agent, 2 parts of antioxidant, wherein the diluent is vegetable oil, and the auxiliary The suspension is a mixture of 10% to 30% oil and wax, and the antioxidant is a food-grade antioxid...

Embodiment 2

[0045] An embodiment of the traditional Chinese medicine soft capsule for treating ankylosing spondylitis of the present invention, the traditional Chinese medicine soft capsule described in this embodiment includes a capsule fluid and a capsule shell, and the capsule fluid is composed of a Chinese medicine extract and a pharmaceutical auxiliary material. The mass ratio of the Chinese medicine extract to the pharmaceutical excipient is 1:1.4, and the Chinese medicine extract is composed of the following components by weight: 25 parts of Clematis clematis extract, 30 parts of Ivy vine extract, 35 parts of Rhizoma Drynariae extract part, 10 parts of Achyranthes bidentata extract; the pharmaceutical adjuvant consists of the following components by weight: 10 parts of diluent, 8 parts of suspending agent, 3 parts of antioxidant, wherein the diluent is vegetable oil, and the auxiliary The suspension is a mixture of 10% to 30% oil and wax, and the antioxidant is a food-grade antioxid...

Embodiment 3

[0048] An embodiment of the traditional Chinese medicine soft capsule for treating ankylosing spondylitis of the present invention, the traditional Chinese medicine soft capsule described in this embodiment includes a capsule fluid and a capsule shell, and the capsule fluid is composed of a Chinese medicine extract and a pharmaceutical auxiliary material. The mass ratio of the Chinese medicine extract to the pharmaceutical excipient is 1:1.5, and the Chinese medicine extract is composed of the following components by weight: 30 parts of Clematis clematis extract, 30 parts of Ivy vine extract, 30 parts of Rhizoma Rhizoma Rhizoma part, 10 parts of Radix Achyranthes Radix Extract; described pharmaceutical excipient is made up of the component of following parts by weight: diluent 11 parts, suspending agent 7 parts, antioxidant 4 parts, wherein said diluent is vegetable oil, and described auxiliary The suspension is a mixture of 10% to 30% oil and wax, and the antioxidant is a food...

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Abstract

The invention discloses a Chinese medicine soft capsule for treating the ankylosing spondylitis and a preparation method thereof. The Chinese medicine soft capsule comprises capsule fluid and a capsule shell, the capsule fluid is composed of Chinese medicine extracts and pharmaceutic adjuvant, and the Chinese medicine extracts are composed of the following ingredients, by weight, 20-40 parts of a radix clematidis extract, 20-40 parts of a sinomenium acutum extract, 20-40 parts of a drynaria rhizonme extract and 10-20 parts of a radix achyranthis bidentatae extract. The Chinese medicine soft capsule is convenient to dose, rapid in effect initiating, high in bioavailability and good in stability, the capsule fluid contains the Chinese medicine extracts with the enough concentration so that the effects of dispelling wind and eliminating dampness, promoting meridian and blood and nourishing kidney and activating blood can be achieved, and the Chinese medicine soft capsule has notable curative effects on various kinds of ankylosing spondylitis patients.

Description

technical field [0001] The invention relates to a Chinese patent medicine and a preparation method thereof, in particular to a traditional Chinese medicine soft capsule for treating ankylosing spondylitis and a preparation method thereof. Background technique [0002] Ankylosing spondylitis (AS), also known as deforming spondylitis, atrophic spondylitis, bamboo spondylosis, etc., is a chronic progressive, independent, systemic disease of unknown etiology. AS belongs to the category of "big hunchback" and "stubborn numbness" in traditional Chinese medicine. It is a disease mainly characterized by chronic inflammation of the axial joints. The lesions mainly involve the sacroiliac joints, the small intervertebral joints of the spine, and the hips, knees, and ankles of the lower limbs. Joints and other large joints. In the early stage of clinical practice, back stiffness and pain are the main symptoms. Chronic progression and prolonged healing can cause spinal rigidity and fibr...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/716A61K36/72A61K9/48A61K47/44A61K47/42A61K47/10A61P19/08A61P29/00A61P19/02
CPCA61K9/4825A61K9/4858A61K36/12A61K36/126A61K36/21A61K36/264A61K36/59A61K36/716A61K36/72A61K47/10A61K47/42A61K2236/331A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 王信
Owner AFFILIATED HOSPITAL OF ZUNYI MEDICAL COLLEGE
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