Clarifying technology for drug compound with effects of treating face, whitening and fading speckles and quality control method

A quality control method and composition technology, applied in the direction of drug combinations, medical preparations containing active ingredients, pharmaceutical formulas, etc.

Inactive Publication Date: 2017-12-22
GUANGZHOU QINGLAN BIOTECHNOLOGY CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0015] At present, there are no relevant reports at home and abroad that the combination of extracts of red ginseng, Pyracantha fruit, Coleus forskohlii, mulberry, trillium and saxifrage extracts has the effect of whitening and lightening the face

Method used

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  • Clarifying technology for drug compound with effects of treating face, whitening and fading speckles and quality control method
  • Clarifying technology for drug compound with effects of treating face, whitening and fading speckles and quality control method
  • Clarifying technology for drug compound with effects of treating face, whitening and fading speckles and quality control method

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Embodiment Construction

[0053] A clarification process and quality control method of a pharmaceutical composition with facial whitening and blemish-relieving effects of the present invention, the clarification process is carried out as follows:

[0054] Clarification process and content of each component

[0055] (1) Preparation of clarifying agent: Type II ZTC1+1 natural clarifying agent consists of A and B components. Component A: Precisely measure 1.0g of component A, add a small amount of distilled water, stir to form a paste, then add distilled water to prepare 100mL of viscose, swell for 24 hours, and filter with double gauze. Component B: Precisely measure 1.0g of component B, add a small amount of acetic acid solution with a volume fraction of 1%, stir it into a paste, then add 1% acetic acid solution to prepare 100mL viscose solution, swell for 24 hours, use Double-layer gauze filter, that is.

[0056] (2) Adding sequence of clarifiers A and B: According to the instructions, ZTC natural cl...

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PUM

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Abstract

The invention discloses a clarifying technology for a drug compound with effects of treating face, whitening and fading speckles and a quality control method. The drug is prepared from six medicinal materials, including rubia yunnanensis, pyracantha fortuneana fruit, coleus forskohlii, mulberry, Trillium tschonoskii and saxifraga stolonifera. The specific clarifying technology includes the step of utilizing II-type ZTC 1+1 natural clarifying agent to clarify the drug compound extract solution. The specific quality control method comprises the steps of utilizing a thin-layer chromatography to perform thin-layer identification on the pyracantha fortuneana fruit, mulberry and Trillium tschonoskii in the drug compound and adopting a high performance liquid chromatography for determining the content of 2-methyl-1,3,6-trihydroxy-9,10-anthraquinone-3-O-(6'-O-acetyl)-alpha-rhamnosyl(1-2)-beta-glucoside, isoforskolin and gallic acid in the drug compound. The clarifying technology and the quality control method adopted by the invention have the advantages that the equipment cost is low, the operation technology is simple, the defects of high alcohol consumption, complex ethyl alcohol recycling, complex determination method for drug multi-components and the like of the traditional alcohol precipitation method are overcome, the inherent quality, curative effect and stability of the compound are quickly and effectively guaranteed and the controllability for the quality standard of drug compound is promoted.

Description

technical field [0001] The invention adopts a clarification process of a natural clarifier and a modern analysis and detection instrument to detect traditional Chinese medicine preparations. The technical field relates to a clarification process and a quality control method of a pharmaceutical composition with the effect of whitening and lightening the face. Background technique [0002] As the saying goes, "one white covers three ugliness", people have longed for a beautiful face and a moony face, as white as jade, since ancient times. Oriental women have always advocated fair skin, and whitening skin is what every girl pursues. The "Chinese Skin Typology" report hosted by Professor De La Chali, an expert in dermatology at the L'Oreal Life Science Institute, pointed out: "Compared with European women, the first thing Chinese women show in the process of skin aging is the problem of pigmentation. , and hyperpigmentation increases with age". Therefore, in China, freckle-rem...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/896A61P17/00G01N30/02G01N30/06G01N30/90
CPCA61K36/185A61K36/53A61K36/605A61K36/73A61K36/74A61K36/896A61K2236/333A61K2236/53A61K2236/55G01N30/02G01N30/06G01N30/90A61K2300/00
Inventor 王恩瀚陈文龙陈汉坤
Owner GUANGZHOU QINGLAN BIOTECHNOLOGY CO LTD
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