The invention relates to a method for preparing no-stimulation talcum powder used for baby, which belongs to the technical field of talcum powder. According to the invention, natural Chinese herbal medicine is taken as a skin protection substance, bacterial invasion on the baby skin can be prevented, loofah sponge is taken as a carrier, hydrogen peroxide is used for bleaching, phosphatidylcholine bilayer is modified to increase the activity on the surface of the loofah sponge, a skin protection substance is loaded, when the perspiration is absorbed, the perspiration is released, so that skin can be better protected, the amino acid content is increased by adding the pearl powder, and smoothness of the skin is increased. The method takes the natural Chinese herbal medicines as the skin protection substance, the natural vegetable fiber is taken as the carrier, the pearl powder is taken as a nutriment which is natural and harmless, no stimulation is generated on skin, and the problems that the traditional talcum powder takes powdered steatile as a main material, the powdered steatile is easily deposed on the surface of fallopian tube or ovary of girl baby, epithelial hyperproliferation is stimulated, cancer is induced, and the stimulation is large to baby skin can be solved.