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Medical disinfectant ultrasonic coupling agent and preparation method thereof

An ultrasonic coupling agent and disinfection type technology, which is applied in the direction of disinfectants, botany equipment and methods, echo/ultrasonic imaging agents, etc., can solve the problem of affecting the ultrasonic effect, not having disinfection function, and the disinfectant is corrosive to the ultrasonic probe, etc. problems, achieve low cost, avoid cross-infection, and do not pollute clothes

Inactive Publication Date: 2017-12-22
贺海霞
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, traditional medical ultrasonic coupling agents only have acoustic properties and do not have disinfection functions; existing disinfectants such as triclosan and chlorhexidine acetate are insoluble in water, and when combined with water-soluble carbomer matrix, they will produce turbidity and affect the ultrasonic effect. And the disinfectant is corrosive to the ultrasound probe

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] A medical disinfectant ultrasonic coupling agent, which consists of the following raw materials in parts by weight: 2.5% polyethylene glycol, 0.3% sodium carboxymethyl cellulose, 0.1% volatile oil of Perrin, 0.1% volatile oil of A. Extract 0.5%, Scutellaria baicalensis extract 0.5%, Senecio extract 0.5%, Radix isatidis extract 0.5%, Comfrey extract 0.5%, Fangfeng extract 0.5%, Carbomer 0.3%, Triclosan 0.01%, No Water ethanol 0.15%, propyl p-hydroxybenzoate 0.12%, purified water 93.32%.

[0017] The preparation method of the medical disinfection type ultrasonic coupling agent of the present embodiment is:

[0018] (1) Take 75% of the purified water and heat it to 45°C, add carbomer, triclosan, and sodium carboxymethylcellulose in sequence while stirring, and homogenize in vacuum for 3 minutes to obtain Sol A;

[0019] (2) Take another 10% of the amount of purified water, add polyethylene glycol and absolute ethanol to it, stir evenly, add propyl p-hydroxybenzoate, Perri...

Embodiment 2

[0023] A medical disinfectant ultrasonic coupling agent, which consists of the following raw materials in parts by weight: 5% polyethylene glycol, 0.5% sodium carboxymethyl cellulose, 0.5% volatile oil of Perrin, 0.5% volatile oil of Shixianglei volatile oil, 0.5% volatile oil of Artemisia argyi, Ligusticum chuanxiong Extract 1.5%, Scutellaria baicalensis extract 1.5%, Senecio extract 1.5%, Radix isatidis extract 1.5%, Comfrey extract 1.5%, Fangfeng extract 1.5%, Carbomer 0.6%, Triclosan 0.05%, No Water ethanol 0.35%, propyl p-hydroxybenzoate 0.32%, purified water 82.68%.

[0024] The preparation method of the medical disinfection type ultrasonic coupling agent of the present embodiment is:

[0025] (1) Take 80% of the amount of purified water and heat it to 55°C, add carbomer, triclosan, and sodium carboxymethylcellulose in sequence while stirring, and homogenize in vacuum for 10 minutes to obtain Sol A;

[0026] (2) Take another 15% of the amount of purified water, add poly...

Embodiment 3

[0030] A medical sterilizing ultrasonic coupling agent, which consists of the following raw materials in parts by weight: 3.75% polyethylene glycol, 0.4% sodium carboxymethyl cellulose, 0.3% perrin volatile oil, 0.3% volatile oil of Shixianglei volatile oil, 0.3% volatile oil of Artemisia argyi, Ligusticum chuanxiong Extract 1%, Scutellaria baicalensis extract 1%, Senecio extract 1%, Radix isatidis extract 1%, Comfrey extract 1%, Fangfeng extract 1%, Carbomer 0.45%, Triclosan 0.03%, No Water ethanol 0.25%, propyl p-hydroxybenzoate 0.22%, purified water 88%.

[0031] The preparation method of the medical disinfection type ultrasonic coupling agent of the present embodiment is:

[0032] (1) Heat 80% of the purified water to 50°C, add carbomer, triclosan, and sodium carboxymethylcellulose in sequence while stirring, and homogenize in vacuum for 7 minutes to obtain Sol A;

[0033] (2) Take another 12% of the amount of purified water, add polyethylene glycol and absolute ethanol t...

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Abstract

The invention discloses a medical disinfectant ultrasonic coupling agent and a preparation method thereof, which belong to the technical field of medical ultrasonic. The ultrasonic coupling agent is prepared from the following raw materials: polyethylene glycol, sodium carboxymethylcellulose, herba eupatorii volatile oil, Mosla chinensis Maxim volatile oil, folium artemisiae argyi volatile oil, rhizoma chuanxiong extract, radix scutellariae extract, herba senecionis scandentis extract, radix isatidis extract, radix arnebiae seu lithospermi extract, radix saposhnikoviae extract, Carbomer, triclosan, absolute ethyl alcohol, propyl p-hydroxybenzoate and purified water. The ultrasonic coupling agent is aromatic in fragrance, has a sterilizing and disinfectant effect, does not damage a probe, is non-irritating to the skin and free from allergenicity, avoids the cross infection of the clinical ultrasonic examination, does not pollute clothes, and is easy to clean, low in cost and good in stability; moreover, the medical disinfectant ultrasonic coupling agent is good in conduction effects, good in lubricating performance, easy to unfold, and good in safety, imaging effects and image resolution.

Description

technical field [0001] The invention belongs to the technical field of medical ultrasound, in particular to a medical disinfection type ultrasonic coupling agent and a preparation method thereof. Background technique [0002] With the continuous improvement of medical technology in our country, ultrasonography and treatment have become an important diagnosis and treatment technology. During ultrasound examination, the air between the probe and the patient's skin will hinder the transmission of ultrasonic waves into the human body. In order to obtain high-quality images, a liquid conductive medium is needed to connect the probe and the patient's body surface. This medium is the couplant. The quality of the couplant is closely related to the quality of the obtained sonogram. Poor quality couplant can cause loss of ultrasonic energy, lower resolution, blurred images, and even irritate the skin and damage the probe. The clinically used coupling agent is mainly gel component in...

Claims

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Application Information

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IPC IPC(8): A61K49/22A01N65/22A01N31/16A01P1/00
CPCA61K49/22A01N31/16A01N65/00A01N65/08A01N65/10A01N65/12A01N65/22
Inventor 贺海霞
Owner 贺海霞
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