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Traditional Chinese pharmaceutical composition for treating ischemic stroke

A technology for ischemic stroke and traditional Chinese medicine, applied in the directions of drug combination, pharmaceutical formula, cardiovascular system diseases, etc., can solve problems such as improving curative effect, aggravating heat stasis, injuring yin and changing dryness, etc., achieving controllable quality, easy storage, Ease of use

Active Publication Date: 2018-01-09
ZHEJIANG CHINESE MEDICAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, Chinese patent medicines for the treatment of this disease are mostly based on qi deficiency and blood stasis. They are treated by nourishing qi and promoting blood circulation or medicines for promoting blood circulation (Buyang Huanwu Decoction, Naoxintong Capsule, Naofukang, Naoluoan, etc.), although they are curative, they are easy to aggravate the fever Blood stasis, easy to cause injury to yin and dryness, cerebral hemorrhage, cerebral ischemia-reperfusion injury and other disadvantages, the curative effect also needs to be improved

Method used

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  • Traditional Chinese pharmaceutical composition for treating ischemic stroke
  • Traditional Chinese pharmaceutical composition for treating ischemic stroke
  • Traditional Chinese pharmaceutical composition for treating ischemic stroke

Examples

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Effect test

Embodiment 1

[0025] Raw material formula: 20 parts of astragalus, 20 parts of kudzu root, 15 parts of Chuanxiong, 10 parts of Morinda officinalis, 10 parts of Dilong, 10 parts of Radix Radix, 10 parts of Scutellaria baicalensis, 10 parts of Radix Paeoniae Rubra, 10 parts of Chuan Duan;

[0026] Preparation method: Astragalus, Pueraria root, Chuanxiong, Morinda officinalis, Dilong, Ophiopogon japonicus, Scutellaria baicalensis, Chishao, Chuanduan, the above 9 traditional Chinese medicines, using 10 times the amount of 70% ethanol as a solvent, soaked for 3 hours, and refluxed to extract 2 times, 1.5 hours each time, filter the extract, recover the ethanol from the filtrate under reduced pressure until it has no alcohol smell, and concentrate it into a clear paste with a relative density of 1.10±0.02 (50-60°C) for later use; the obtained dregs are reused 8 times Measure water as a solvent, boil and extract twice, each time for 1.5h, filter the extract, concentrate the filtrate into a clear pa...

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PUM

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Abstract

The invention provides a traditional Chinese pharmaceutical composition for treating ischemic stroke. The traditional Chinese pharmaceutical composition is prepared from active ingredients of radix astragali seu hedysari, radix puerariae lobatae, rhizoma chuanxiong, radix morindae officinalis, lumbricus, radix ophiopogonis, radix scutellariae, radix paeoniae rubra and radix dipsaci. The traditional Chinese pharmaceutical composition disclosed by the invention has the advantages of simple technology and controllable quality. The traditional Chinese pharmaceutical composition disclosed by the invention has the effects of reducing encephaledema, reducing brain vascular permeability, resisting oxygen deficit, dissolving fibrous protein by activating plasminogen, dissolving thrombus and the like. Meanwhile, the traditional Chinese pharmaceutical composition disclosed by the invention passes strict safety control like animal toxicity tests and the like, is suitable for ischemic stroke involving both collateral and meridian qi and yin deficiency, heat stasis collateral blocking syndrome, hemiplegia, mouth and tongue skew, sluggish speech, hemianesthesia, strength lack, dull red tongue, uneven pulse or sunken and string-like pulse and the like and has an obvious curative effect.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicines, in particular to a combination of traditional Chinese medicines for treating ischemic stroke. Background technique [0002] Ischemic stroke has the characteristics of high morbidity, disability, mortality, and recurrence, and the incidence is still increasing year by year. Stroke is the second deadliest disease in the world, and 87% of strokes are ischemic strokes (thrombosis or embolism); in 2008, the third national cause of death survey by the Ministry of Health showed that the number of stroke deaths in my country (136.64 / 100,000 ) has exceeded the number of deaths from malignant tumors (135.88 / 100,000) as the leading cause of death; 1.5 million people die of stroke in my country every year, accounting for 51% of the total annual death causes; there are 6-7 million survivors, 40% Severely disabled, 70% lost the labor force to varying degrees. There are complex pathological changes ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8968A61K9/16A61P9/10A61K35/62
Inventor 万海同周惠芬何昱万嘉洋杨洁红虞立
Owner ZHEJIANG CHINESE MEDICAL UNIVERSITY
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