New purpose of antithrombin III and kit

An antithrombin and kit technology, which can be used in biological testing, material testing, etc., and can solve problems such as limited application

Active Publication Date: 2018-01-12
唐颐生物医学(天津)有限公司 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there are very few studies on this enzyme at home and abroad, which limits its clinical application.

Method used

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  • New purpose of antithrombin III and kit
  • New purpose of antithrombin III and kit
  • New purpose of antithrombin III and kit

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] Embodiment 1 A kind of test kit for detecting or assessing TBI patient's injury condition

[0030] The kit includes substances for detecting antithrombin III, microtiter plate, standard, buffer, enzyme-labeled antithrombin III antibody diluent, washing solution, stop solution; the kit is used for detecting antithrombin Substance III is an enzyme-labeled rabbit anti-thrombin III antibody.

Embodiment 2

[0031] Embodiment 2 A kind of test kit for detecting or assessing TBI patient's injury condition

[0032] The kit includes substances for detecting antithrombin III, microtiter plate, standard, buffer, enzyme-labeled antithrombin III antibody diluent, washing solution, stop solution; the kit is used for detecting antithrombin The substance of III is an enzyme-labeled anti-thrombin III antibody;

[0033] Wherein, the enzyme-labeled anti-thrombin III antibody diluent is a phosphate buffer solution containing 0.75% sodium chloride and 2% polyethylene glycol 400 in mass fraction, and the concentration of the phosphate buffer solution is 1mol / L.

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Abstract

The invention provides new purpose of antithrombin III and a kit, which have the benefits that a substance used for detecting the antithrombin III can be used for evaluating the injury state of a TBIpatient or used for detection and auxiliary detection on the severity of the injury state of the to-be-evaluated TBI patient; when being used for evaluating or detecting the severity of the injury state of the TBI patient, the method has the advantages of being good in specificity, high in sensitivity, good in reproducibility, good in patient compliance and the like. A test proves that the antithrombin III can be taken as a marker for evaluating the severity of the injury state of the TBI patient and can also be used for evaluating the severity of the injury state of the TBI patient; results are accurate, the operation is simple and convenient, and the application value is large.

Description

technical field [0001] The invention belongs to the application field of antithrombin III, and in particular relates to a new application and kit of antithrombin III. Background technique [0002] Traumatic Brain Injury (TBI) is an important factor affecting human health in the world. Because it can occur in occasions closely related to human life, such as traffic accidents, work, and sports, it has a very high incidence rate. Recent statistics show that 2 million TBIs occur each year in the United States, and 43% of TBI patients will be left with disabilities. According to statistics, 1 million TBIs occur every year in China, and according to Chinese head trauma data (Chinese Head Trauma Data Bank, CHTDB), the mortality rate of TBI patients can reach 21.8%. [0003] According to the degree of injury, TBI can be divided into mild, moderate and severe TBI. The classification method is mainly based on the Glasgow Coma Scale (GCS), that is, in TBI, patients with a GCS score ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N33/68
Inventor 程世翔张赛徐忠伟衣泰龙曹毓琳
Owner 唐颐生物医学(天津)有限公司
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