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A kind of fossil composition of Tibetan medicine Manuo Decoction and its preparation method

A composition and fossil technology, applied in the directions of drug combination, pharmaceutical formula, plant raw material, etc., can solve the problems of inconvenience in taking, outdated process, and different formulation and quantity, and achieve the effects of controllable quality, stable process and convenient taking.

Active Publication Date: 2020-06-02
青海省藏医药研究院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The fossil composition, through pharmacological tests, determines the formula quantity, verifies the effectiveness and safety, and adopts modern pharmaceutical equipment and technology such as ultrafine pulverization, vacuum drying, centrifugal spray drying, etc. to make granular preparations, which not only eliminates the effect of calculus It is strong and effective, and it also solves the problems of different prescriptions, backward technology, uncontrollable quality, and inconvenient consumption of traditional Manuo soup.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] Prescription of Manuo Decoction Fossil Granules (parts by weight):

[0036] 12.8 parts of clasp wood and 12.8 parts of wide tendon rattan

[0037] 25.6 parts of Tibetan woody incense, 6.4 parts of fire nitrate, 6.4 parts of Naosha

[0038] Preparation process: put Tibetan woody incense, wide tendon rattan, and Rubus wood in a multi-functional extraction tank, add 8 times the amount of clean water, decoct and extract 3 times, each extraction time is 3 hours, combine the filtrates, and concentrate to relative density It is more than 1.3, and the dry extract powder is obtained by drying with a centrifugal spray dryer.

[0039] Grind fire salt and nacre sand respectively, pass through 800-200 mesh sieve, mix the obtained powder with dry extract powder passed through 40-200 mesh sieve, add 85% ethanol, make soft material, granulate on granulator, dry, and granulate , packaging, wherein the drying temperature is lower than 80°C.

Embodiment 2

[0041] Prescription of Manuo Decoction Fossil Granules (parts by weight):

[0042] 12.8 parts of clasp wood and 12.8 parts of wide tendon rattan

[0043] 25.6 parts of Tibetan woody incense, 6.4 parts of fire nitrate, 6.4 parts of Naosha

[0044] Preparation process: Grind Tibetan woody incense, broad tendon vine and rabus wood, put them in a multi-functional extraction tank, add 6 times the amount of clean water, decoct and extract twice, each extraction time is 5h, combine the filtrates, and concentrate to the relative The density is more than 1.3, and it is dried with a centrifugal spray dryer to obtain dry extract powder. Grind fire salt and nacre sand respectively, pass through 80-200 mesh sieve, mix the obtained powder with dry extract powder passed through 40-200 mesh sieve, add 85% ethanol, make soft material, granulate on granulator, dry, and granulate , packaging, wherein, the drying temperature is not higher than 80 ℃.

Embodiment 3

[0046] Prescription of Manuo Decoction Fossil Granules (parts by weight):

[0047] 12.8 parts of clasp wood and 12.8 parts of wide tendon rattan

[0048] 25.6 parts of Tibetan woody incense, 6.4 parts of fire nitrate, 6.4 parts of Naosha

[0049] Preparation Process:

[0050] 1) Grind the fire salt and Nao sand respectively and pass through a sieve of 80-200 meshes to obtain fire salt powder and Nao sand powder.

[0051]2) Weigh the medicinal materials of Tibetan woody incense, Rubus chinensis, and broad tendon rattan in the prescribed amount, and coarsely crush them through a 10-mesh sieve to form a coarse powder. Put the coarse powder in a multifunctional extraction tank, add 8 times the amount of clean water, distill and extract the volatile oil for 8 hours, decoct and extract 3 times, each extraction time is 1 hour; the volatile oil is sealed and refrigerated, the filtrate is combined, and concentrated to a relative density of more than 1.1 , add 8 times the amount of 8...

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Abstract

The invention discloses a Tibetan medicine Manuoxitang fossil composition or particles thereof as well as a preparation method thereof. The fossil composition is prepared by the following medicinal materials in parts by weight: 20-30 parts of Ramulus rubi, 10-15 parts of roots of Inula racemosa, 10-15 parts of Tinospora sinensis, 5-7.5 parts of potassium nitrate, and 5-7.5 parts of sal ammoniac. The fossil composition has efficacies for treating and preventing renal calculus and cystolith with good safety and effectiveness.

Description

technical field [0001] The invention belongs to the field of Tibetan medicine pharmacy, and in particular relates to a fossil composition of Tibetan medicine Manuo Decoction and a preparation method thereof. Background technique [0002] The basic prescription of Tibetan medicine Siwei Zangmuxiang Granules was first recorded in the classic of Tibetan medicine "Sibu Medical Code". It is composed of four medicinal materials: Zangmuxiang, Rubus wood, broad tendon rattan and dried ginger. It has an important position and value in the traditional prescriptions of Tibetan medicine. It is a characteristic medicinal method of Tibetan medicine to treat diseases by adding or subtracting the taste of medicine according to the condition. Based on the raspberry and the broad tendon rattan, according to the theory of Tibetan medicine, the "Manuo Decoction" series of decoctions for the treatment of various diseases have been derived. This series of decoctions is the most characteristic of ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/73A61K9/16A61P13/12A61P13/04A61P13/10A61K33/00A61K33/02
Inventor 多杰马志良赛桑杰
Owner 青海省藏医药研究院