47results about "Ammonia active ingredients" patented technology

The invention discloses traditional Chinese medicine suspension eye drops and a preparation method thereof, and the traditional Chinese medicine suspension eye drops are prepared from the following raw materials in parts by weight: 1-3 parts of a traditional Chinese medicine composition, 4-7 parts of hydroxypropyl-beta-cyclodextrin, 0.5-2 parts of microcrystalline cellulose-sodium carboxymethyl cellulose and auxiliary materials. The traditional Chinese medicine suspension eye drops provided by the invention abandon a traditional eye ointment form, are directly dropped for use, are convenient to use, have good stability and dispersity, and are excellent in use curative effect and medication experience; on the basis of keeping the clinical efficacy of the Marcher eight-treasure ancient prescription, secondary development and research are scientifically carried out, so that the Marcher eight-treasure ancient prescription plays a greater clinical treatment role, and has a wider market development prospect.

The invention belongs to the field of medicines, and particularly relates to application of a cough relieving agent in preparation of an anti-influenza virus medicine. Through the synergistic effects of resisting viruses, resisting inflammation, regulating mucus secretion and inhibiting nerve sensitization, the antitussive agent relieves influenza symptoms and promotes recovery from the source, has the advantages of being stable in curative effect, small in toxic and side effect, not prone to generating drug resistance, not capable of promoting virus variation and the like, is wider in application stage and application crowd, and can intervene in the early stage of influenza infection. Due to the fact that the antitussive agent can treat influenza caused by exogenous cold and influenza viruses, the antitussive agent can be used in time to relieve symptoms when cough, excessive phlegm and other symptoms are found in the early stage of a patient, the antitussive agent can relieve the exogenous cold for a non-influenza patient, and the antitussive agent can prevent influenza from being converted into severe influenza from mild influenza for an influenza patient. And the reduction of the treatment effect caused by definite diagnosis delay and oseltamivir treatment delay is also avoided.

The invention discloses a traditional Chinese medicine composition for treating tumors. The invention belongs to the medical field of traditional Chinese medicine for treating tumors. The medicine consists of 21 traditional Chinese medicines such as artemisia anomala, pseudo-ginseng, pseudobulbus cremastrae seu pleiones, rhizoma paridis, dried alum, sal ammoniac and ground beeltle, and comprises plant medicines, mineral medicines and animal medicines. According to the theory that tumor formation is mostly caused by qi and blood stasis, phlegm-damp toxin and stagnation and accumulation and is essentially blood death, stubborn phlegm and rotten water, the traditional Chinese medicine composition is prepared by adopting the method of regulating qi, promoting blood circulation to remove blood stasis, softening hardness to dissipate stagnation, eliminating phlegm, dredging collaterals, clearing away heat and toxic materials, relieving pain, removing rotten water and inducing diuresis as well as strengthening body resistance to eliminate pathogenic factors according to the principle of syndrome differentiation and treatment of traditional Chinese medicine. The method is an empirical method gradually formed by continuous exploration in the practice process. The medicine has a treatment effect on tumors; the traditional Chinese medicine composition also has the effect of relieving and easing pain caused by tumors.

The present invention may be directed to compositions and methods for the treatment of alopecia / epilation, which may include the treatment of alopecia conditions. Compositions and methods relate to oral supplements of oral minoxidil, including an SLC22A9 inducer, an HIF-alpha inducer, and / or an acidulant. Acidification of blood in patients with alopecia may cause mild acidosis, which may up-regulate SLC22A9 and / or down-regulate AABC3. Inducing SLC22A9, inducing HIF-alpha, and / or acidifying the patient's blood can promote oral form of minoxidil into hair follicles.

This invention belongs to the field of traditional Chinese medicine technology and discloses drugs and methods of administration for preventing and treating viral infections and tumors. The drugs for preventing and treating viral infections and tumors are divided into two components. By weight, component one includes 0.5-25 parts of ginseng, 1-20 parts of astragalus, 1-18 parts of gastrodia, 1-24 parts of earthworm, 1-26 parts of chuanxiong, 0.1-15 parts of salvia miltiorrhiza, 0.1-10 parts of borneol, 1-28 parts of notoginseng, 1-32 parts of pinellia, 0.1-14 parts of centipede, and 0.1-17 parts of leech. Component two includes 1.5-2.5 parts of borax, 0.5-1.5 parts of potassium nitrate, 1.5-2.5 parts of sal ammoniac, 2-4 parts of agarwood, 4-6 parts of malachite, and 2-4 parts of borneol. This invention combines prevention and treatment. For uninfected individuals, the first component spray can effectively prevent viral infection, while for confirmed patients, the second component powder can kill viruses and tumors, resulting in good therapeutic effects and preventing the disease from worsening and spreading.

Compositions and methods are provided for treating dental caries in individuals and animals. The compositions may be zinc compositions of [Zn(NH3)4]F2. Also provided are methods for producing inorganic zinc compounds (e.g., ZnO, Zn(OH)2, or Zn(OH)F) on the surface of carious lesions. The deposition of inorganic zinc compounds (e.g., ZnO, Zn(OH)2, or Zn(OH)F) reduces the amount of Zn 2+ This can occur by diluting a ZnO / NH3 solution (e.g., an aqueous or alcohol-based solution) into water (e.g., deionized water). The formation of inorganic zinc compounds (e.g., ZnO, Zn(OH)2, or Zn(OH)F) can occur instantaneously upon dilution.

Described herein are articles comprising a nitric oxide releasing compound and dextran bonded to at least one surface of the article, wherein a sulfonated triazine is covalently bonded to dextran. In one aspect, the articles bind to albumin, which can reduce clotting at the surface of the article and the risk of thrombosis.

An object of the present invention is to provide a liposome composition and a pharmaceutical composition, which exhibit a high AUC. Provided are a liposome composition including a hydrophilic polymer-modified diacylphosphatidylethanolamine, a dihydrosphingomyelin, and cholesterols as components of a liposome membrane, in which the liposome composition encapsulates a drug, an inner water phase thereof contains ammonium sulfate, and a molar ratio of sulfate ions in the inner water phase to the drug in an entire water phase is 0.36 or more; and a pharmaceutical composition including the liposome composition.

The invention discloses a multi-level targeting composite hydrogel microsphere based on amino fullerene and an application of the multi-level targeting composite hydrogel microsphere based on amino fullerene, methylacrylate modified aldehyde hyaluronic acid is used as a matrix carrier, amino fullerene is combined with the matrix carrier, and the methylacrylate modified aldehyde hyaluronic acid-fullerene composite hydrogel microsphere is obtained. The macroscopic-cell-mitochondrial multi-layer slow-release targeting effect is achieved, ROS is remarkably reduced in vitro / in vivo, and cartilage repair is promoted. Compared with the prior art, the invention has remarkable innovativeness in targeting precision, release control and curative effect, and is suitable for precise treatment of joint diseases.

Embodiments can relate to compositions and methods for the treatment of hair loss, which can include treatment of alopecia. The compositions and methods relate to an oral supplement to oral minoxidil includes a SLC22A9 inducer, a HIF-alpha inducer, and / or an acidifying agent. Acidifying blood of a patient suffering from alopecia can cause mild acidosis which can up-regulate SLC22A9 and / or down-regulate AABC3. Inducing SLC22A9, inducing HIF-alpha, and / or acidifying blood of the patient can facilitate oral forms of minoxidil to enter hair follicles.

Plant-based medicinal compounds or nutritional supplements in various carrier combinations are described. The carriers can include N-acylated fatty amino acids, penetration enhancers, and / or various other beneficial carriers. The plant-based composition / carrier combinations can create administration benefits.

The invention discloses a traditional Chinese medicine composition for treating nasosinusitis, an external ointment and a preparation method and application thereof. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 45 to 55 parts of flos magnoliae liliflorae, 55 to 65 parts of radix angelicae, 25 to 35 parts of flos genkwa, 45 to 55 parts of fructus gleditsiae, 75 to 85 parts of leech, 115 to 125 parts of maggot, 95 to 105 parts of centipeda minima, 25 to 35 parts of fructus xanthii, 55 to 65 parts of muskmelon base, 25 to 35 parts of herba asari, 15 to 25 parts of borneol, 5 to 15 parts of menthol and 15 to 25 parts of sal ammoniac. The biond magnolia flower and the cocklebur fruit are used as monarch drugs, the radix angelicae, the centipeda minima and the asarum are used as ministerial drugs, the lilac daphne flower bud, the leech, the maggot, the muskmelon base, the fructus gleditsiae and the sal ammoniac are used as adjuvant drugs, and the borneol and the menthol are used as conductant drugs, so that a compound structure of dredging orifices, expelling pus and guiding channels is formed, and the traditional Chinese medicine composition is suitable for phlegm-heat congestion type nasosinusitis and is quick in effect and high in cure rate.

Embodiments may relate to compositions and methods for treating hair loss, which may include treating alopecia. The compositions and methods relate to oral supplements to oral minoxidil, including an SLC22A9 inducer, a HIF-α inducer, and / or an acidifying agent. Acidifying the blood of patients suffering from alopecia can cause mild acidosis, which can upregulate SLC22A9 and / or downregulate AABC3. Induction of SLC22A9, induction of HIF-α, and / or acidifying the patient's blood can facilitate the entry of oral forms of minoxidil into hair follicles.

The invention relates to the technical field of biomedicine, in particular to application of hydrated electrons or a hydrated electron preparation in preparation of products for reducing uric acid and resisting inflammation or oxidation. The hydrated electron and the preparation thereof are found to be capable of effectively reducing the uric acid level, have antioxidant and anti-inflammatory effects, have obvious improvement and treatment effects on hyperuricemia, gout and inflammation and lesion of kidneys and joints caused by hyperuricemia and gout, do not have toxic or side effects and adverse reactions on animals, and are suitable for clinical application. The compound has a good application prospect in treatment of hyperuricemia and gout, and a new treatment means is provided for hyperuricemia and gout.

The invention discloses a traditional Chinese medicine lozenge for treating esophageal cancer, which comprises the following medicinal materials: 40 g of borax, 10 g of agilawood, 25 g of potassium nitrate, 9 g of chlorite schist, 10 g of borneol, 9 g of sal ammoniac, 9 g of clove, 30 g of pseudo-ginseng, 1.5 g of musk and 20 g of granulated sugar, and relates to the technical field of traditional Chinese medicine lozenges. The traditional Chinese medicine composition has the effects of inhibiting cancer cell proliferation and preventing metastasis and relapse, has small burden on the body and is beneficial to disease control.

This disclosure provides the use of nanoparticles of self-assembled acidic molecular clusters (NP-AMCs) of ammonium salts to lower the pH of skin and underlying tissue of a human or other mammal as a means of stimulating the localized immune response to a wound.

This disclosure provides the use of molecular complexes of polyammonium bisulfate alone and in combination with certain metals or metal salts to treat burn wounds.

Provided is compositions and methods for treating dental caries in individuals and animals. The compositions may be zinc compositions of [Zn(NH3)4]F2. Also provided are methods of making inorganic zinc compounds (e.g., ZnO, Zn(OH)2, or Zn(OH)F) onto the surface of a carious lesion. The deposition of inorganic zinc compound (e.g., ZnO, Zn(OH)2, or Zn(OH)F) may occur from dilution of a Zn2+ / NH3 solution (e.g., an aqueous or alcohol-based solution) into water (e.g., deionized water). The formation of inorganic zinc compound (e.g., ZnO, Zn(OH)2, or Zn(OH)F) may be instantaneous upon dilution.

Provided is compositions and methods for treating dental caries in individuals and animals. The compositions may be zinc compositions of [Zn(NH3)4]F2. Also provided are methods of making inorganic zinc compounds (e.g., ZnO, Zn(OH)2, or Zn(OH)F) onto the surface of a carious lesion. The deposition of inorganic zinc compound (e.g., ZnO, Zn(OH)2, or Zn(OH)F) may occur from dilution of a Zn2+ / NH3 solution (e.g., an aqueous or alcohol-based solution) into water (e.g., deionized water). The formation of inorganic zinc compound (e.g., ZnO, Zn(OH)2, or Zn(OH)F) may be instantaneous upon dilution.

Synthetic ionophores for the active carry and transport of free ions across biological membranes in vivo, comprising coordination complexes of molecules with polarized hexa-aqua and / or tetra-aqua syst

The invention discloses a traditional Chinese medicine preparation for treating chronic esophagitis and esophageal precancerous lesions and a preparation method thereof. The traditional Chinese medicine preparation is prepared from nux vomica, sal ammoniac, sculellaria barbata, Chinese lobelia, duchesnea indica, marsdenia tenacissima, solanum septemlobum bunge, selfheal, processed pinellia ternate, ginger, coptis chinensis, sticktight, airpotato yam, radix clematidis, borax, platycodon grandiflorum, hawthorn, kelp, seaweed, edible tulip and venenum bufonis. The preparation method comprises the following steps: processing or performing raw treatment on the materials, grinding into fine powder by using a grinder, finely screening by using a sieve, removing coarse stems, and mixing in parts by weight to obtain a finished product of the preparation. The traditional Chinese medicine is simple in preparation method and low in cost, can dissipate blood stasis, regulate liver and stomach and nourish stomach yin, and can effectively treat chronic esophagitis and esophageal precancerous lesions.

A dental composition is described that includes a homogeneous solution having a zinc complex stabilized with an amine-containing ligand and a fluoride anion source. A method for treating or preventing caries activity on a tooth surface using the dental composition is also described, as are kits.

A method of treating severe forms of PH, including PAH, in a patient is provided. The method includes administering at least one copper chelator comprising a tetrathiomolybdate (TTM) salt. The method may further include administering at least one active agent that enhances treatment such as methotrexate, inhibitors of the 5-lipoxygenase enzyme (5-LO), rituximab, baicalin, inhibitors of immune checkpoints CTLA-4, PD-1 and PDL-1, bufalin, quercetin, curcumin, integrins, inhibitors of NF-kappaB, and focal adhesion kinase inhibitors. Also provided is a composition including the TTM salt and the at least one active agent.

Several embodiments of NO releasing compounds are disclosed. In some embodiments, the structures are covalently modified to store and release nitric oxide. Some embodiments pertain to methods of making and use of these structures. The compounds may be tailored to release nitric oxide in a controlled manner and can be useful, for example, for treating or preventing microbial infections, or reducing the microbial load of a microbial infection.

The invention belongs to the technical field of biological medicines, and particularly relates to a biological cell regulating solution, a preparation method of the regulating solution and application of the regulating solution in the aspects of virus resistance, inflammation resistance and immune regulation. The method has the advantages that by accurately controlling the dilution concentration of the electromagnetic base liquid and key parameters such as the reduction potential and the pH value of the diluent, it is ensured that hydration electrons in the diluent can form a stable quantum state structure, and a foundation is laid for the subsequent biological regulation function. The biological cell regulation liquid is applied to anti-inflammatory, anti-virus and immune regulation, the function that one liquid has multiple purposes is achieved, overlapped medication is not needed, and the medicine has the advantages of being efficient in virus resistance (the virus inactivation rate exceeds 95%), high in selectivity (not affecting normal cells), rapid in effect, lasting and stable in regulation effect, free of excessive immune reaction risk and the like; in addition, the functions of various immune cells can be synchronously enhanced in the aspect of immune regulation, and comprehensive immune regulation is truly realized. In the anti-inflammatory aspect, accurate anti-inflammation can be achieved, the inflammatory factor level is remarkably reduced, the normal physiological function is not affected, the biocompatibility is good in use, and no accumulative side effect exists.

To provide ammonia-oxidizing bacteria for treatment of acne.SOLUTION: A method for treating skin disorders, for example acne, e.g., acne vulgaris, in a subject is provided. This method comprises administering a preparation containing an ammonia oxidizing bacterium to the surface of the subject, for example applying, for example, topically administering. Also provided is a preparation containing an ammonia oxidizing bacteria for treating skin disorders, for example acne, e.g., acne vulgaris, in a subject. The administration, for example the amount and frequency of application may be sufficient to reduce the amount or concentration of pathogenic bacteria, for example Propionibacterium acnes, on the surface of the subject.SELECTED DRAWING: None

Hypertonic pharmaceutical compositions are disclosed. The hypertonic pharmaceutical compositions contain an anti-platinum chemoprotectant agent and a gelling agent. Also disclosed are methods of medical use of the hypertonic pharmaceutical compositions.