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Attenuated total reflection microfluidic prism for detecting trace liquid terahertz spectrum and manufacturing method

An attenuated total reflection, trace liquid technology, applied in the field of liquid-phase sample terahertz spectrum detection, can solve the problems of high detection cost, unfavorable volatile samples, toxic and harmful samples detection, etc., and achieve the effect of saving sample volume and avoiding contact.

Active Publication Date: 2020-11-20
CHONGQING INST OF GREEN & INTELLIGENT TECH CHINESE ACADEMY OF SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

The amount of detection is expensive for rare samples and expensive samples
In addition, the liquid bearing pool of the general attenuated total reflection prism is an open structure, which is not conducive to the detection of volatile samples, toxic and harmful samples

Method used

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  • Attenuated total reflection microfluidic prism for detecting trace liquid terahertz spectrum and manufacturing method
  • Attenuated total reflection microfluidic prism for detecting trace liquid terahertz spectrum and manufacturing method
  • Attenuated total reflection microfluidic prism for detecting trace liquid terahertz spectrum and manufacturing method

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Embodiment Construction

[0032] The preferred embodiments of the present invention will be described in detail below with reference to the accompanying drawings.

[0033] Such as figure 1 As shown, the present invention is an attenuated total reflection microfluidic prism, which includes an attenuated total reflection prism body 1 and a cover sheet 2. The attenuated total reflection prism body 1 is in the shape of a triangular prism. Among the three cylindrical surfaces, one of the rectangular surfaces is a total reflection surface 12, and the remaining two rectangular surfaces are terahertz wave coupling surfaces 11;

[0034] The cover sheet 2 is arranged on the total reflection surface, and the surface of the cover sheet 2 is provided with a micro-channel structure 21, and at least two through holes 22 are provided to run through the micro-channel structure 21, and the through holes 22 are used for liquid sampling or When the sample is taken out, the cover sheet 2 is closely attached to the total r...

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Abstract

The invention relates to an attenuated total reflection microfluidic prism for detecting micro fluid terahertz wave spectrum and a manufacturing method thereof, and belongs to the technical field of liquid phase sample terahertz wave spectrum detection. The attenuated total reflection microfluidic prism comprises an attenuated total reflection prism main body and a cover plate, wherein the attenuated total reflection prism main body is in a triangular prism shape; in three cylindrical surfaces, one rectangular surface is a total reflection surface; the rest two rectangular surfaces are terahertz wave coupling surfaces; the cover plate is arranged on the total reflection surface; a micro-channel structure is arranged on the surface of the cover plate; a through hole is also formed for communicating with the micro-channel structure; the through hole is used for liquid sample feeding or sample outlet; the cover plate is tightly attached to the total reflection surface. The detection sample quantity of the traditional attenuated total reflection mode is reduced to be dozens of microliters; the attenuated total reflection microfluidic prism is very suitable for the detection of valuablesamples and rare samples; meanwhile, tested liquid is sealed through microflow, so that the attenuated total reflection microfluidic prism is very suitable for the detection of volatile samples and toxic and harmful samples.

Description

technical field [0001] The invention belongs to the technical field of liquid phase sample terahertz spectrum detection, and relates to an attenuated total reflection microfluidic prism for detecting trace liquid terahertz spectrum and a manufacturing method thereof. Background technique [0002] Terahertz spectroscopy has been widely used in various biochemical detection fields. Attenuated total reflection is an effective method for liquid sample terahertz detection. Attenuated total reflection is to measure the interaction information between the evanescent wave on the surface of the total reflection prism and the sample, resulting in a spectrum similar to the transmission absorption. The evanescent wave propagates tangentially along the interface and decays exponentially in amplitude with increasing distance from the outer surface of the crystal. In the terahertz band, the evanescent wave can interact with the liquid tens to hundreds of microns above the total reflectio...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G01N21/01G01N21/3586G01N21/3577
CPCG01N21/01G01N21/3577G01N21/3586
Inventor 张明焜魏东山杨忠波汤明杰颜识涵张华王化斌崔洪亮
Owner CHONGQING INST OF GREEN & INTELLIGENT TECH CHINESE ACADEMY OF SCI
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