Capsule and process for preparing same

A preparation process and capsule technology, which is applied in the field of medicine, can solve the problems of unsatisfactory curative effect, large toxic and side effects, and high price, and achieve the effects of being easy to take, store and transport, ensuring smooth progress, and conducive to retention

Inactive Publication Date: 2018-05-29
INNER MONGOLIA TIANQI HAN&MONGOLIA PHARMA CO +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, Western medicine is commonly used in the treatment of coronary heart disease, which is expensive and has very high toxicity and side effects. However, the application of traditional Chinese medicine or adjuvant therapy can only relieve the pain of patients, but cannot cure it, and the curative effect is not satisfactory.

Method used

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  • Capsule and process for preparing same
  • Capsule and process for preparing same
  • Capsule and process for preparing same

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0047] 1. Prescription:

[0048]

[0049] 2. Preparation process:

[0050] Soak sandalwood, baldwood, red sandalwood, and nutmeg in a predetermined proportion, add 7 times the amount of water, soak for 2 hours, and reflux for 8 hours to obtain volatile oil, dregs, steam distillate and water extract, and set aside; Add a saturated aqueous solution containing 4.5g of β-cyclodextrin, and incubate at 65°C for 2 hours to obtain a volatile oil inclusion compound for later use; take a predetermined proportion of Salvia miltiorrhiza, add 9 times the amount of 90% ethanol and heat and reflux for extraction 3 times. After 1.5 hours, the dregs of Danshen are used for later use; the extract is filtered, and the filtrate is concentrated to a clear ointment with a relative density of 1.04 for later use; 65% ethanol, heated and refluxed for 3 times, each time for 1.5 hours, the extract was filtered, the filtrate was concentrated to a clear paste with a relative density of 1.05, and set a...

Embodiment 2

[0052] 1. Prescription:

[0053]

[0054]

[0055] 2. Preparation process:

[0056] Soak sandalwood, baldwood, red sandalwood, and nutmeg in a predetermined proportion, add 8 times the amount of water, soak for 2 hours, and reflux for 8 hours to obtain volatile oil, medicinal residues, steam distillate and water extract, and set aside; Add a saturated aqueous solution containing 4g of β-cyclodextrin, and incubate at 60°C for 2 hours to obtain a volatile oil inclusion compound for later use; take a predetermined proportion of Salvia miltiorrhiza, add 10 times the amount of 90% ethanol and heat and reflux for extraction 3 times, each time After 1.5 hours, the dregs of Danshen are used for later use; the extract is filtered, and the filtrate is concentrated to a clear ointment with a relative density of 1.05 for later use; 60% ethanol, heat and reflux for extraction twice, each time for 2 hours, filter the extract, concentrate the filtrate to a clear paste with a relative ...

Embodiment 3

[0058] 1. Prescription:

[0059]

[0060] 2. Preparation process:

[0061] Soak sandalwood, baldwood, red sandalwood, and nutmeg in a predetermined proportion, add 9 times the amount of water, soak for 2 hours, and reflux for 8 hours to obtain volatile oil, dregs, steam distillate and water extract, and set aside; Add a saturated aqueous solution containing 3.5g of β-cyclodextrin, and carry out inclusion complexation at 50°C for 2.5 hours to obtain a volatile oil inclusion compound for later use; take a predetermined proportion of Salvia miltiorrhiza, add 10 times the amount of 80% ethanol and heat and reflux for extraction 3 times, each After 1 hour, the dregs of salvia miltiorrhiza are used for later use; the extract is filtered, and the filtrate is concentrated to a clear paste with a relative density of 1.05 for later use; 60% ethanol, heated and refluxed twice, each time for 2.5 hours, the extract was filtered, the filtrate was concentrated to a clear paste with a rel...

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Abstract

The invention discloses a capsule. The capsule comprises 420-450 parts of radix salviae miltiorrhizae, 43-48 parts of lignum santali albi, 90-100 parts of lignum dalbergiae odoriferae, 43-48 parts oflignum pterocarri, 135-150 parts of semen myristicae, 135-148 parts of fructus choerospondiatis, 140-150 parts of fructus hippophae, 210-225 parts of lignum aquilariae resinatum, 125-138 parts of fructus piperis longi and 68-75 parts of rhizome of galanga resurrectionlily. The invention further provides a process for preparing the capsule. The capsule and the process have the advantages that effective components can be advantageously reserved as compared with the traditional decoction, the categories and the usage of excipients are screened, accordingly, capsule filling can be assuredly smoothly carried out on the capsule, and the accuracy of the loading capacity of the capsule can be guaranteed; various experimental conditions for the process for preparing the capsule are screened and optimized, accordingly, effective medicine components in medicinal materials can be sufficiently and effectively extracted, and the effective components can be assuredly reserved; capsule preparations are prepared from the capsule and accordingly are convenient to take, store and transport.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a Guanxin Huoxue capsule and a preparation process thereof. Background technique [0002] The incidence of coronary heart disease among middle-aged and elderly people is getting higher and higher, and there is a trend of younger patients. Patients with coronary heart disease are usually accompanied by palpitations, angina pectoris, cardiac insufficiency, etc., unable to engage in physical labor, seriously unable to take care of themselves, and even die. At present, Western medicine is commonly used in the treatment of coronary heart disease, which is expensive and has very large toxic and side effects. However, the application of traditional Chinese medicine treatment or auxiliary treatment can only alleviate the suffering of patients, but cannot cure it, and the curative effect is not satisfactory. [0003] Therefore, there is an urgent need for traditional Chinese...

Claims

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Application Information

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IPC IPC(8): A61K36/906A61K9/48A61K47/69A61P9/10
Inventor 佘宜寰韩风雨于秀玲李洪泽
Owner INNER MONGOLIA TIANQI HAN&MONGOLIA PHARMA CO
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