Application of SPECC1L for medicine for treating liver cancer and/or postoperatively preventing liver cancer recurrence

Abstract

The invention discloses application of a SPECC1L gene for medicine for treating the liver cancer and / or postoperatively preventing liver cancer recurrence, namely application of the SPECC1L gene for medicine for treating the liver cancer and / or inhibiting liver cancer postoperative cancer cell proliferation, invasion and metastasis. The invention further discloses a pharmaceutical composition fortreating the liver cancer and / or postoperatively treating liver cancer recurrence. According to various means, it is found that the SPECC1L gene is highly expressed in the liver cancer cell line and liver cell cancer tissue, and high expression of the SPECC1L gene is closely related to total postoperative life time and disease-free survival time and unhealthy clinicopathologic features of a patient suffering from the liver cell cancer; it is found that high expression of the SPECC1L gene in the liver cell cancer tissue is an independent risk factor affecting liver cancer long-term survival prognosis; the SPECC1L gene can promote liver cancer cell proliferation, invasion and metastasis. Accordingly, the SPECC1L gene can be applied to preparing medicine for treating the liver cancer and / or inhibiting liver cancer postoperative cancer cell proliferation, invasion and metastasis.

Description

technical field [0001] The present invention relates to the field of liver cancer treatment, in particular to the application of a SPECC1L gene in the treatment of liver cancer and / or the drug for preventing the recurrence of liver cancer after operation. Background technique [0002] Liver cancer is one of the most common malignant tumors in the world. According to the latest statistics, there are 554,000 new cases of liver cancer in men worldwide every year, ranking fifth among all male tumors; 228,000 new cases are newly diagnosed in women every year, ranking eighth among all female tumors. Liver cancer accounts for 5.7% of all cancer deaths in the world every year. The incidence of liver cancer in developing countries is significantly higher than in developed countries. According to statistics, more than half of global liver cancer occurs in Asia, which seriously threatens human life and health. Although the diagnostic techniques of liver cancer and comprehensive trea...

AI Technical Summary

Problems solved by technology

[0003] The present invention provides the application of a kind of SPECC1L gene in the medicine of treating liver cancer and / or preventing the recurrence of liver cancer after operation, so as to solve the technical problem that the liver cancer cells in patients with liver cancer are easy to proliferate and invade and metastasize in the human body, leading to the spread of cancer cells

Images