Appliance Device for detecting chemical product in reaction kettle in on-line manner

Abstract

The invention relates to an appliance for detecting device for on-line detection of a chemical product in a reaction kettle in an on-line manner. The appliance device comprises the reaction kettle, aRaman spectrum detection system and a controller, wherein the reaction kettle comprises a kettle body; the kettle body is connected with a heating unit; the heating unit comprises a heating componentand multiple temperature sensors; the temperature sensors are connected with the controller; the Raman spectrum detection system comprises a laser device, an optical fiber sensor and a Raman spectrometer; the Raman spectrometer is connected with the controller; the optical fiber sensor comprises a light scattering probe; the light scattering probe comprises a probe and a detector directly facing the probe; the probe is connected with the laser device through an input optical fiber; the detector is used for receiving laser light from the probe and emitting scattered light; the probe is used forcollecting the scattered light and transmitting the scattered light to the Raman spectrometer through the input optical fiber; the controller receives an output signal of the Raman spectrometer; thedetector comprises a planar pedestal and a nano array located on the surface of the pedestal, and the nano array is formed by multiple conical carbon nanotubes.

Description

technical field [0001] The invention relates to the technical field of chemical product detection, in particular to a device for on-line detection of chemical products in a reaction kettle. Background technique [0002] At present, in the process of drug synthesis, the general practice for the detection of products at various stages of the reaction is to take samples from the reaction vessel and then perform chromatographic analysis, but the time required for chromatographic analysis is relatively long. For the detection of unstable products, The timeliness of the detection is very important. If it is left for a long time for detection, the concentration or structure of the product will change significantly, and the accuracy of the detection results cannot be guaranteed. As an analytical method, Raman spectroscopy is widely used in the fields of chemistry, biology, and medicine due to its unique advantages such as rich information, simple sample preparation, and small water ...

AI Technical Summary

Problems solved by technology

However, one of the main limitations of the application of Raman spectroscopy is that the Raman scattering signals obtained from micro-trace chemical substances are very weak, which reduces the applicable range of its detection and increases the difficulty of detection.

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