Application and medicine of Malan or Malan extract in preparation of medicine for treating non-infectious inflammation
A non-infectious, extractive technology, applied in the field of medicine, can solve the problems of low patient tolerance, long treatment period of non-infectious enteritis, and poor curative effect, so as to reduce physical pain, eliminate psychological panic, and improve tolerance. Effect
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[0030] A more preferred method is the heating reflux extraction method. More specifically, the preparation method of the Malan extract comprises: heating the Malan extract to reflux at 75-90° C. for 2-3 hours with 45-55 wt % ethanol solution, and filtering the obtained The dregs are heated and refluxed at 75-90° C. with 45-55 wt % ethanol solution for 1-2 hours, and the filtrates obtained from two extractions are combined and concentrated under reduced pressure to obtain Malan extract.
[0031]More preferably, after the Malan extract is extracted by solvent extraction, the Malan extract is obtained; subsequently, the Malan extract is extracted with a low-polarity solvent, and the obtained large polar part is the Malan extract. The specific process is: remove the organic solvent in the obtained Malan extract, keep the water phase, then add a certain volume of low polarity solvent to the water phase for extraction, extract 2 to 3 times, and extract the obtained The water phase w...
Embodiment 1
[0036] The present embodiment provides a kind of medicine for treating radiation enteritis, and this medicine is oral liquid, and its preparation method is:
[0037] Fresh whole Malan herb is 1kg, quickly wash the roots to carry the sediment, and cut into sections. Add about 5L of water to a glass container and decoct, keep boiling slightly for 30 minutes after boiling, pour out the liquid medicine, add an appropriate amount of preservatives, subpackage, 250mL / bottle, and then make an oral liquid with a content of about 200g fresh medicinal materials / L. One bottle at a time, swallow slowly, and finish within 1 hour. Take 3 times a day.
Embodiment 2
[0039] The present embodiment provides a kind of medicine for treating radiation enteritis, and this medicine is granule, and its preparation method is:
[0040] Dry 10kg of Malan whole herb, crush it into coarse powder, add 80L of 50% ethanol to heat and extract in a stainless steel traditional Chinese medicine extraction tank, reflux for 2 hours, and obtain the extract after filtering. The residue was extracted with 50 L of 50% ethanol under reflux for 1 hour, and the extract was obtained after filtration. The extracts obtained twice were combined, and the ethanol was recovered under reduced pressure until there was no alcohol smell, and about 55 L of concentrated solution was obtained. The concentrated solution was extracted twice with petroleum ether, each time the volume of the concentrated solution was 1 / 2. Separate the aqueous phase and concentrate it to 10L.
[0041] Take 5kg of glucose and 4kg of sucrose and mix them as an absorbent; use a fluidized bed granulator, ...
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