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Tylosin injection liquid as well as preparation method and application thereof

A technology of tylosin and injection, which is applied in pharmaceutical formulations, medical preparations without active ingredients, and medical preparations containing active ingredients, etc. The problem of large body stimulation, etc., can increase the effect time, reduce the number of drugs, and reduce the stimulation effect.

Inactive Publication Date: 2018-09-14
FOSHAN NANHAI EASTERN ALONG PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Most of the tylosin injections sold in the market are acid-type tylosin tartrate injections, which have the disadvantages of high viscosity, short duration of drug action, many times of injection administration and great stimulation to the body.

Method used

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  • Tylosin injection liquid as well as preparation method and application thereof
  • Tylosin injection liquid as well as preparation method and application thereof
  • Tylosin injection liquid as well as preparation method and application thereof

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Embodiment Construction

[0019] The technical solutions of the present invention will be described in detail below in conjunction with specific embodiments, but the following are only specific implementations of the present invention, and are not intended to limit the protection scope of the present invention.

[0020] A tylosin injection provided by the embodiment of the present invention includes the following components and contents: basic tylosin: 1.0-30.0%, drug slow-release agent: 1.0-15.0%, surfactant: 1.0-10.0%, analgesic: 1.0-5.0%, solvent: 1.0-30.0%, and the rest is water for injection.

[0021] Among them, as a preferred implementation scheme, the ratio of tylosin basic to drug sustained-release agent is (1.8-2.2): 1, and the ratio of tylosin basic to surfactant is (2.2-2.8) : 1. As a further preferred implementation scheme, the ratio of basic tylosin to drug slow-release agent is 2:1, and the ratio of basic tylosin to surfactant is 2.5:1.

[0022] Wherein, as a possible implementation, t...

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Abstract

The invention discloses a tylosin injection liquid as well as a preparation method and application thereof. The tylosin injection liquid comprises the following components in content: 1.0-30.0% of alkali tylosin, 1.0-15.0% of a medicine slow-release agent, 1.0-10.0% of a surfactant, 1.0-5.0% of a pain killer, 1.0-30.0% of a solution medium and the balance of injection water. As an injection is directly prepared from the alkali tylosin, the treatment effect of a medicine can be greatly improved, and drinking times can be reduced; meanwhile, due to adoption of the high-performance medicine slow-release agent, the medicinal effect lasting time can be prolonged; in addition, by adopting the injection disclosed by the invention, the medicine viscosity can be effectively reduced, and irritationto animal bodies can be reduced.

Description

technical field [0001] The invention relates to a tylosin injection and a preparation method and application thereof. Background technique [0002] As a worldwide problem in the field of public health, the prevention and control of Swine streptococcosis not only leads to serious global public health events, but also brings great economic losses to the breeding industry. The economic loss caused is as high as more than 3 million U.S. dollars. In my country, streptococcal suis has spread out in more than 20 provinces and cities, and the mortality rate of sick pigs is as high as 88%. Streptococcus suis often causes meningitis, septicemia, endocarditis, arthritis, pneumonia and other diseases in pigs. Humans get sick through contact infection, leading to neurological deafness and even death. Due to the complex serotypes of the bacteria, there is no ideal vaccine available, so antibiotics are still an important measure to prevent and treat the disease. [0003] As one of the spe...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/08A61K31/7048A61K45/06A61K47/32A61K47/38A61K47/22A61P11/00A61P1/12
CPCA61K31/7048A61K9/0019A61K9/08A61K45/06A61K47/22A61K47/32A61K47/38A61K2300/00
Inventor 叶伟庆
Owner FOSHAN NANHAI EASTERN ALONG PHARMA CO LTD
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