57 results about "Pain killers" patented technology

An aerosol container 190a provided with an outer container 11, a collapsible inner bag 12 inserted in the outer container, and a valve 13. The inner bag 12 comprises an upper and lower chamber 27, 26 and the chambers are divided at a constriction part formed in the middle of the inner bag by a partitioning member 72. The valve 13 has communicating holes that communicates valve 13 with the upper chamber 27 and the lower chamber 26 through a dip tube 28. An inner bag type aerosol product may be obtained by charging different kind of contents A and B into the container. Two-liquid reaction type agents, such as hair dye. enzyme hair dye, hair dress agent or setting agent for hair, reduction of inflammation pain killer, anti-heat flushes, coolants, pack agents, cleansing agents, shaving foams, moisturizers, antipersipirants. vitamin preparations, emollients and etc. may be preferably used for the combination of the contents for aerosol product.

Compositions and related methods for treating IBS and other gastrointestinal disorders and conditions (e.g., gastrointestinal motility disorders, functional gastrointestinal disorders, gastroesophageal reflux disease (GERD), duodenogastric reflux, Crohn's disease, ulcerative colitis, inflammatory bowel disease, functional heartburn, dyspepsia (including functional dyspepsia or nonulcer dyspepsia), gastroparesis, chronic intestinal pseudo-obstruction (or colonic pseudoobstruction), and disorders and conditions associated with constipation, e.g., constipation associated with use of opiate pain killers, post-surgical constipation, and constipation associated with neuropathic disorders as well as other conditions and disorders are described. The compositions feature peptides that activate the guanylate cyclase C (GC-C) receptor.

The present invention relates to a high-frequency thermotherapy device. More specifically, when a detection signal related to normal muscularity and abnormal muscularity, inputted through a sensor module, is received, the high-frequency thermotherapy device automatically changes the detection signal to have a frequency of 2 to 5 MHz in a frequency adjustment oscillation module of an impedance detection unit, and generates a high frequency in a high-frequency generation unit according to an impedance value, so as to provide the changed frequency to the location of the abnormal muscularity or skin, thereby enabling a treatment effect for deformation or various inflammations of the abnormal muscularity without damaging the normal muscularity and a reduction in the amount of a pain-killer used by alleviating pain, selectively adjusting an output from among three stages of strong, intermediate and weak according to a state of an affected part in a control panel unit of a display, adjusting voltage settings, and receiving power from a second power source unit and control a ceramic member to sequentially generate deep heat according to a set time of a timer in a control unit.

Compositions and related methods for treating IBS and other gastrointestinal disorders and conditions (e.g., gastrointestinal motility disorders, functional gastrointestinal disorders, gastroesophageal reflux disease (GERD), duodenogastric reflux, Crohn's disease, ulcerative colitis, inflammatory bowel disease, functional heartburn, dyspepsia (including functional dyspepsia or nonulcer dyspepsia), gastroparesis, chronic intestinal pseudo-obstruction (or colonic pseudoobstruction), and disorders and conditions associated with constipation, e.g., constipation associated with use of opiate pain killers, post-surgical constipation, and constipation associated with neuropathic disorders as well as other conditions and disorders are described. The compositions feature peptides that activate the guanylate cyclase C (GC-C) receptor.

The current invention provides peptide nucleic acid derivatives targeting the 3' splice site of exon 4 in the human SCN9A pre-mRNA. The peptide nucleic acid derivatives potently induce SCN9A mRNA splice variant(s) lacking the SCN9A exon 4 in cells, and are useful to safely treat pains or conditions involving Nav1.7 activity.