Anesthetic and preparation method and use method thereof

Abstract

The invention belongs to the technical field of medicines, and particularly discloses an anesthetic. According to the anesthetic, propofol is used as a basic medicament, and a chamomile extract, astragalus powder, mentholum, radix notoginseng powder and a flos daturae extract are used as auxiliary medicaments. The invention further provides a preparation method and a use method of the anesthetic. By adoption of a western and traditional Chinese medicine combined technology, under the condition of keeping the original propofol medicament effect, the pain easing function is enhanced; furthermore, a more serious circulation suppression and breathing suppression effect caused by the propofol is effectively improved; during use, the use amount of a cooperatively used pain killer is reduced, the side effect of the medicament is reduced, and the clinical safety is improved.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to an anesthetic. Background technique [0002] Propofol, whose chemical name is 2,6-diisopropylphenol, is a new type of rapid and short-acting intravenous anesthetic commonly used clinically for induction of anesthesia, maintenance of anesthesia, and sedation of critically ill ICU patients. Propofol injection is a white isotonic intravenous injection, containing 10 mg of dipropofol per milliliter, refined soybean oil, refined egg yolk lecithin, glycerin and water for injection, etc. This product is a short-acting intravenous anesthetic of alkylphenols, which exerts sedative and hypnotic effects by activating the GABA receptor-chloride ion complex. In clinical doses, propofol increases chloride ion conduction, and in large doses, it desensitizes GABA receptors, thereby inhibiting the central nervous system, producing sedative and hypnotic effects, and its anesthetic po...

AI Technical Summary

Problems solved by technology

[0003] In the current clinical anesthesia application, propofol is mostly used for intravenous compound anesthesia. Propofol has strong vasodilation, myocardial inhibition and respiratory depression, which often leads to more serious circulatory depression and respiratory depression, especially when combined with opioids. Respiratory depression is more obvious when taking drugs, and propofol anesthesia does not have analgesic properties. During anesthesia, it is necessary to use analgesics to relieve pain, which increases the risk of anesthesia and adverse reactions, and the scope of clinical application is limited.