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Bacteriostatic and antiviral traditional Chinese medicine gel composition

A gel composition and antiviral technology, applied in the directions of antiviral agents, drug combinations, antibacterial drugs, etc., can solve problems such as vaginal microenvironment imbalance, affect treatment, easily cause drug resistance, etc., and restore the balance of vaginal flora , Inhibit the reproduction of bacteria and achieve the effect of vaginal flora balance

Inactive Publication Date: 2018-09-18
HUNAN QIANJIN MEADOW HEALTH PROD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] However, antibiotic sterilization is not selective, and will kill the beneficial bacteria in the vagina, resulting in an imbalance in the vaginal microenvironment. Long-term use may also easily lead to drug resistance, affecting subsequent treatment

Method used

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  • Bacteriostatic and antiviral traditional Chinese medicine gel composition

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Experimental program
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Effect test

Embodiment 1

[0056] Lactobacillus salivarius, Lactobacillus rhamnosus, Bifidobacterium bifidum, and Streptococcus thermophilus were used as fermentation strains, and whey was used as fermentation substrate, fermented at 40°C for 6 hours, and the clarified supernatant was filtered to obtain probiotics Bacterial fermentation liquid;

[0057] 5 parts by weight of probiotic fermented liquid, 1 part by weight of Phellodendron cork concentrate, 1 part by weight of Sophora flavescens concentrate, 0.05 part by weight of rosemary essential oil, 15 parts by weight of witch hazel extract, 15 parts by weight of seaweed peptide extract, menthol 0.1 parts by weight, 0.3 parts by weight of nano silver, 0.3 parts by weight of triclosan, 1 part by weight of carbomer, 1.15 parts by weight of triethanolamine, 10 parts by weight of sorbitol, EGCG palmitate (epigallocatechin gall palmitate) 0.08 parts by weight, tea polyphenols 0.1 parts by weight, solubilizer C0400.35 parts by weight, and purified water to 10...

Embodiment 2

[0061] Lactobacillus salivarius, Lactobacillus rhamnosus, Bifidobacterium bifidum, Streptococcus thermophilus were used as fermentation strains, whey was used as fermentation substrate, fermented at 45°C for 8 hours, and the clarified supernatant was filtered to obtain probiotics Bacterial fermentation liquid;

[0062] 1 part by weight of probiotic fermented liquid, 1 part by weight of Phellodendron cork concentrate, 1 part by weight of Sophora flavescens concentrate, 0.05 part by weight of rosemary essential oil, 15 parts by weight of witch hazel extract, 15 parts by weight of seaweed peptide extract, menthol 0.1 parts by weight, 0.1 parts by weight of nano silver, 0.1 parts by weight of triclosan, 1 part by weight of carbomer, 1.15 parts by weight of triethanolamine, 10 parts by weight of sorbitol, EGCG palmitate (epigallocatechin gall palmitate) 0.08 parts by weight, tea polyphenols 0.1 parts by weight, solubilizer C0400.35 parts by weight, and purified water to 100 parts b...

Embodiment 3

[0066] Lactobacillus salivarius, Lactobacillus rhamnosus, Bifidobacterium bifidum, Streptococcus thermophilus were used as fermentation strains, whey was used as fermentation substrate, fermented at 40°C for 10 hours, and the clarified supernatant was filtered to obtain probiotics Bacterial fermentation liquid;

[0067] 10 parts by weight of probiotic fermented liquid, 1 part by weight of Phellodendron cork concentrate, 1 part by weight of Sophora flavescens concentrate, 0.05 part by weight of rosemary essential oil, 15 parts by weight of witch hazel extract, 15 parts by weight of seaweed peptide extract, menthol 0.1 parts by weight, 0.3 parts by weight of nano silver, 0.3 parts by weight of triclosan, 1 part by weight of carbomer, 1.15 parts by weight of triethanolamine, 10 parts by weight of sorbitol, EGCG palmitate (epigallocatechin gall palmitate) 0.04 parts by weight, tea polyphenols 0.1 parts by weight, solubilizer C0400.35 parts by weight, and purified water to 100 part...

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Abstract

The invention provides a bacteriostatic and antiviral traditional Chinese medicine gel composition, which is prepared from the following ingredients in parts by weight: 1 to 10 parts of probiotic fermentation liquid, 0.1 to 5 parts of cortex phellodendri concentration solution, 0.1 to 5 parts of radix sophorae flavescentis concentration solution, 0.01 to 5 parts of rosemary essential oil, 5 to 20parts of witch hazel extraction liquid, 5 to 20 parts of seaweed polypeptide extraction liquid, 0.1 to 1 part of menthol, 0.1 to 0.5 part of nanometer silver, 0.1 to 0.5 part of trichloro hydroxydiphenyl ether, 0.2 to 5 parts of Carbomer, 0.3 to 3 parts of triethanolamine, 2 to 20 parts of sorbitol, 0.01 to 0.1 part of EGCG palmitate, 0.01 to 1 part of tea polyphenol, 0.5 to 2 parts of solubilizers C040 and a proper amount of purified water to reach the total quantity of 100 parts. The probiotic fermentation liquid is added, so that the vaginal flora balance is realized.

Description

technical field [0001] The invention belongs to the technical field of medicines, in particular to an important antibacterial and antiviral gel composition Background technique [0002] The normal female vagina has a constant pH value between 3.8 and 4.2, and there are a variety of aerobic and anaerobic bacteria inhabiting it, mainly Lactobacillus. Lactobacillus itself can secrete lactic acid, maintain the normal pH value of the vagina, and at the same time secrete and produce H 2 o 2 , has a toxic effect on other microorganisms and inhibits their reproduction, ensuring the health of the vaginal environment. However, due to the influence of sexual life and bad hygienic habits, the vagina is polluted, causing a large number of bacteria to multiply, and the dominant position of Lactobacillus is destroyed, which causes vaginal inflammation. According to different sources of infection, vaginal inflammation can be divided into: bacteria, fungi, and trichomonas. Typical symptom...

Claims

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Application Information

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IPC IPC(8): A61K36/756A61K47/32A61P15/02A61P31/04A61P31/12A61K9/06A61K31/045A61K31/353A61K33/38
CPCA61K36/756A61K9/06A61K31/045A61K31/353A61K33/38A61K36/185A61K36/489A61K36/53A61K47/32A61K2236/19A61P15/02A61P31/04A61P31/12A61K2300/00
Inventor 王洪孟君邓小波黄雯李丹郑赞
Owner HUNAN QIANJIN MEADOW HEALTH PROD
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