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Application of two compounds in preparing nematocidal drugs

A technology of nematicides and compounds, applied in the direction of nematicides, applications, drug combinations, etc., can solve the problems of high residue and high toxicity, and achieve the effect of preventing and controlling nematode diseases, expelling nematode parasites, and having no toxic side effects

Active Publication Date: 2018-10-09
INST OF TROPICAL BIOSCI & BIOTECH CHINESE ACADEMY OF TROPICAL AGRI SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The existing agricultural nematicides mainly include organophosphorus pesticides such as nematosphate, which have the disadvantages of high toxicity and high residue; medical anthelmintics include albendazole, which also has certain side effects

Method used

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  • Application of two compounds in preparing nematocidal drugs
  • Application of two compounds in preparing nematocidal drugs
  • Application of two compounds in preparing nematocidal drugs

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] Example 1: Agricultural water solvent for preparing the compound of the present invention

[0032] Weigh the raw materials (unit: g) by weight: 6 g each of stilbostemin E and stemanthrene A, Tween-602 g, and 50 mL of water.

[0033] Add 50 mL of Tween-60 and heat to 50-60 degrees Celsius, slowly add stilbostemin E and stemanthrene A respectively, and filter to obtain an aqueous solution.

[0034] For agriculture to kill nematodes, 50mL of the prepared aqueous solution can be diluted to 2000mL with water for spraying or rhizosphere injection.

Embodiment 2

[0035] Example 2: Preparation of capsules of the compound of the present invention

[0036] Weigh each raw material (unit: g) according to the following weight: stilbostemin E and stemanthrene A each 60 g.

[0037] Add stilbostemin E and stemanthrene A to 100 mL of ethanol respectively, filter, add 1.8 g of sodium starch glycolate, mix well, spray-dry to form granules, and fill them into No. 1 capsules to obtain capsules.

Embodiment 3

[0038] Example 3: Preparation of tablets of the compound of the present invention

[0039] Weigh each raw material (unit: g) according to the following weight: stilbostemin E and stemanthrene A each 60 g.

[0040] Add stilbostemin E and stemanthrene A to 100 mL of ethanol, filter, add 1.8 g of sodium starch glycolate, mix well, spray-dry to form granules, and send them to a tablet machine for tableting.

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PUM

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Abstract

The invention relates to the technical field of pesticides and medicines, in particular to application of two compounds in preparing nematocidal drugs. The two compounds disclosed by the invention aresafe and reliable and can effectively prevent and control nematode diseases in agriculture; nematode parasites can be removed for medical use; in addition, the two compounds have no toxic or side effects and drug dependence to a human body, is superior to existing pesticides and medicines, and can be widely used in the preparation of the nematocidal drugs.

Description

Technical field [0001] The present invention relates to the technical fields of pesticides and medicines, in particular to the application of two compounds in the preparation of nematicidal drugs. Background technique [0002] Nematodes refer to the phylum of nematodes. There are many recorded species and can be seen everywhere in the world. Many of them are parasitic. Among them, there are as many as 25 parasitic nematodes recorded in my country. The more popular ones include roundworms, pinworms and hookworms. . With the improvement of medical and health conditions, the infection rate of soil-borne nematodes monitored in my country from 2005 to 2013 decreased from 20.88% to 3.12%, but still a large number of people's health is endangered. Agricultural and forestry nematodes are also very harmful, causing agricultural production to be reduced (such as root-knot nematodes, which are estimated to cause global crop losses of 100 million US dollars), and large areas of tree death (s...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A01N31/16A01P5/00A61K31/09A61P33/10
CPCA01N31/16A61K31/09A61P33/10A61K2300/00
Inventor 黄圣卓梅文莉王辉周丽曼王军戴好富
Owner INST OF TROPICAL BIOSCI & BIOTECH CHINESE ACADEMY OF TROPICAL AGRI SCI
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