242 results about "Hormones levels" patented technology

The various embodiments of the present invention relate to a human identical flowable hormone composition dispersed in a cream or gel contained in the novel “Smart” metered dose applicator, which facilitates numerous patient specific dosing options, dose titration, as well as continuous and variable dosing. The composition is designed for transdermal usage for consumers who follow a specified dosage protocol resulting in static and cyclic variations on serum hormone levels over a 28 day cycle stretched over the span of a month. The regimen is modeled after nature, in an attempt to replicate temporal variations in serum progesterone and estradiol hormone levels of premenopausal females with healthy hormone cycles. A dispenser is also disclosed for flowable cream-base medicaments, specifically; a unidirectional rotatable platform attached to a screw that is slipped into a barrel where it is secured in place and it joins the said components that house an elevator.

Hormone compositions including bioidentical hormones dispersed in a lipid-based cream are provided in syringes for dispensation and self-administration by a user. The compositions, which are topically applied by the user, are percutaneously delivered to the vascular system of the user in accordance with a dosage protocol that causes a rhythmic and cyclic variation in the serum hormone levels that mimics the temporal variation in hormone levels present in the serum of a normal premenopausal woman.

Lactobacillus plantarum having an anti-diabetic function and application thereof are disclosed, the strain is Lactobacillus plantarum NCU116, and the accession number is CGMCC 11885. The strain has a function to alleviate symptoms of diabetes, and the composition is in a form of food or a pharmaceutical composition. The present invention also discloses a method for screening and identification of the lactic acid bacteria strain as well as a method to achieve the anti-diabetic effect by regulating blood sugar, blood lipids and hormone levels and regulating metabolic pathways in the body. The daily-intake lactic acid bacteria or a composition thereof is used to replace a medicine to achieve the anti-diabetic effect; and the healthy daily-intake lactic acid bacteria or the composition thereof is free of toxic and side effects to human body is used as a new choice to alleviate the symptoms of diabetes.

Methods and devices are described for electrically stimulating nerves and organs to induce and modulate the production of hormones according to desired hormone production patterns and hormone level patterns to treat gynecological conditions. Such methods and devices may be used to treat or alleviate the symptoms of menopause. In addition, such methods and devices may be used for birth control.

The present invention provides peptidomimetic macrocycles capable of modulating growth hormone levels and methods of using such macrocycles for the treatment of disease.

The present invention relates to a system for assessing ovarian reserve functions in subjects. The system for assessing the ovarian reserve functions of the subjects comprises a data acquisition module used for obtaining data of a subject's age, an anti-Mullerian hormone (AMH) level, a follicle stimulating hormone (FSH) level and antral follicle counting (AFC); and a module for calculating the ovarian reserve functions used for calculating information obtained in the data acquisition module to calculate a probability (p) of subject's ovarian hyporesponsiveness. Further, a relationship betweenthe predicted ovarian hyporesponsiveness probability and a medicine dose of an ovulation-promoting medicine is predicted to divide populations into four groups in order to group closes ovarian responsiveness into one group.

Hormone compositions comprising bioidentical hormones dispersed in a lipid-based cream are provided in syringes for dispensation and self-administration by a user. The compositions, which are topically applied by the user, are percutaneously delivered to the vascular system of the user in accordance with a dosage protocol that causes a rhythmic and cyclic variation in the serum hormone levels that mimics the temporal variation in hormone levels present in the serum of a normal premenopausal woman.

The present invention relates to the use of control compositions and kits comprising such to evaluate and monitor the consistency of assays utilized to determine parathyroid hormone levels.

The present invention is directed to a method of improving ovarian reserve in a human female with diminished ovarian reserve as measured by the female's anti-Müllerian hormone level. The method may include evaluating a first anti-Müllerian hormone level of the female, administering dehydroepiandrosterone to the female for at least about one month, and evaluating a second anti-Müllerian hormone level of the female, wherein the second anti-Müllerian hormone level is greater than the first anti-Müllerian hormone level.

The invention relates to the technical field of sanitation supplies and especially relates to a biological anti-dandruff and itch-relieving compound and an application thereof. The biological anti-dandruff and itch-relieving compound comprises the following components by weight percent: 2-4% of sweet wormwood extract, 2-4% of pseudo-ginseng root extract, 2-3% of radix sileris extract, 2-3% of folium artemisiae argyi extract, 2-3% of fructus cnidii extract, 1-3% of radix stephaniae extract, 1-3% of sophora flavescens root extract, 0.6% of phenoxyethanol and the balance of water; the mass ratioof sweet wormwood extract to pseudo-ginseng root extract is at 1:1; the mass ratio of radix stephaniae extract to sophora flavescens root extract is at 1:1. The biological anti-dandruff and itch-relieving compound provided by the invention can be used as a functional raw material and can be used for preparing shampoo, hair conditioner and hair gel. The biological anti-dandruff and itch-relieving compound provided by the invention is rich in various natural compound plant polyphenols and has the effects of regulating hormone level and sebum metabolism, efficiently resisting against inflammationand sterilizing, removing dandruff and relieving itch.

The invention relates to a tissue culture propagating method of Tilia miqueliana Maxim, which pertains to the technical field of ligneous plant plantlet vegetative propagation. The invention aims at solving the problem that both seed seedling raising (low seed germination rate and long dormancy stage) and cottage propagation of the Tilia miqueliana Maxim are difficult. The method comprises the following steps: the stem sections with axillary buds at the different ages are taken as explants which are respectively inoculated on inducing culture medium, the best explant is selected based on the bud inducing result; and the best disinfection method is selected by comparing the contamination rates of different disinfection ways; an optimal bud inducing culture medium and an optimal successive propagation culture medium are respectively screened by adopting an L9(3<3>) orthogonal experimental design; based on the successive culture medium, 12 culture media are prepared by adjusting the hormone levels; the best rooting sound plantlet hardening culture medium is screened according to rooting situation. By adopting the experiment, the best tissue culture propagating method of the Tilia miqueliana Maxim is obtained by optimization.

The invention discloses a hatching egg incubation illumination regulating and controlling method and an illumination regulating and controlling device, with side-direction light supply. Egg supports loaded with hatching eggs are placed on each layer of turnable egg stands, LED lamps are mounted above one side or multiple sides of each layer of the turnable egg stands and parallel to the turnable egg stands, and the LED lamps can turn along with the turnable egg stands; or the LED lamps are horizontally, or vertically or obliquely mounted on one side or multiple sides outside three-dimensional egg stands, and the LED lamps do not turn along with the turnable egg stands. After light enters, the hatching eggs perform diffuse reflection on the light, so that the light tends towards uniformity; when the hatching eggs are incubated, the LED lamps are regularly switched on, the light transmits egg shells of the hatching eggs, embryos mutually influence through squirm, and concurrent work and rest rhythm and hormone level are formed, so that the health state of the embryos is increased, the growth of the embryos is promoted, the incubation time is shortened, and the incubation rate of the hatching eggs, and the development and the stress resistant capacity of internal organs of chicks are improved. The hatching egg incubation illumination regulating and controlling method and the illumination regulating and controlling device disclosed by the invention are used for regulating and controlling illumination in the process of incubating the hatching eggs, the design is simple, the structure is reasonable, and the use rate of light energy is greatly increased.

The invention is suitable for the field of nutrition and health care and provides a health food capable of enhancing bone mineral density and immunity and a preparation method of the health food. The health food comprises the following components in percentage by weight: 20%-40% of D-glucosamine, 20%-40% of calcium, 8%-15% of a kudzuvine root extract, 5%-10% of chondroitin sulfate, 2%-5% of casein phosphopeptides, 0.5%-3.3% of colostrum basic protein and the balance of auxiliary materials. According to the health food, bone metabolism is promoted by the modes of restoring or improving the normal physiological functions of the organism, such as regulating the hormone level in the organism, improving the capacity of a bone tissue for actively absorbing osteoblast nutrients, stimulating osteoblast proliferation, self-synthesizing ossein, repairing bones and joints and bone tissues, improving the skeleton micro-structure and improving the bone immunity; the bone health is maintained; and the condition of the bone mineral density is fundamentally improved.

A method of improving cumulative embryo score may comprise administering an androgen to a human female, for example, DHEA, for at least about four consecutive months followed by harvesting and fertilizing oocytes and forming embryos. Between about 50 mg and about 100 mg of DHEA may be administered to a human female per day. Moreover, a method of increasing the quantity of fertilized oocytes in one cycle of in vitro fertilization may comprise administering an androgen to a human female for at least about four consecutive months, harvesting and fertilizing the oocytes. Furthermore, a method of increasing the quantity of day 3 embryos from one cycle of in vitro fertilization may comprise administering an androgen for at least about four consecutive months, harvesting and fertilizing the oocytes and forming day 3 embryos. A method of normalizing ovarian DHEA also may include administering an androgen for at least about four consecutive months. A method of increasing the rate and number of euploid oocytes may include administering an androgen for at least about four consecutive weeks. In addition, a method of increasing male fetus sex ratio may comprise raising baseline androgen levels in a female prior to or at time of embryo implantation.

The invention discloses a Boer breeding goat feeding key technology suitable for the area between the Yangtze River and the Huaihe River. The technology includes the following steps of firstly, selecting breeding sheep to be bred; secondly, feeding rams; thirdly, feeding ewes. The technology is developed according to the unique geographical and climatic environment of the area between the Yangtze River and the Huaihe River, the adaptability of Boer goats to the area between the Yangtze River and the Huaihe River can be improved, the breeding cost of Boer goats is reduced, the reproduction performance of Boer goats can be remarkably improved, the service life of Boer goats can be remarkably prolonged, the litter size is increased, and the birth weight and survival rate of lambs are increased. Feed is prepared respectively according to the physical characteristic difference of breeding rams and ewes, the development state and hormone level of breeding sheep can be easily adjusted and controlled, and therefore the overall quality of Boer goats is improved, and variety optimizing is achieved. The technology has the advantages of being small in breeding risk, short in breeding cycle, high in benefit and the like; scientific and standardized instructions can be provided for farmers, the healthy development of large-scale sheep breeding is ensured, the technological content of sheep breeding is improved, and the high development of large-scale sheep breeding is promoted.

The invention belongs to the technical field of forage and relates to a preparation method of aquarium fish forage. The aquarium fish forage is prepared from wheat malt, fish meal, chicken liver powder, silkworm chrysalis powder, whole egg powder, dry shrimp powder, dehydrated spinach, red yeast rice powder and soybean protein peptide. The aquarium fish forage contains essential nutrients such as proteins, carbohydrates, fat, inorganic salts, vitamins and cellulose, and also contains a red yeast rice pigment, a plurality of digestive enzymes and protein peptides. Through utilization of the aquarium fish forage, aquarium fish has a good color and a high ornamental value. The aquarium fish forage can reduce the amount of harmful microbes in the fish intestinal tract, can improve an internal metabolic hormone level of aquarium fish, can improve disease resistance of aquarium fish and can prolong an aquarium fish life.

The invention belongs to the field of traditional Chinese medicines, relates to a pharmaceutical composition for adjusting estrogen level as well as a preparation method and application thereof, and in particular relates to a method for preparing the pharmaceutical composition. The method comprises the steps of preparing a fructus psoraleae extract and preparing a eucommia ulmoides extract, a radix salviae miltiorrhizae extract and a rhizoma anemarrhenae extract. The invention also relates to the pharmaceutical composition prepared by the method. The pharmaceutical composition comprising the fructus psoraleae extract, the eucommia ulmoides extract, the radix salviae miltiorrhizae extract and the rhizoma anemarrhenae extract is basically free of toxicity for liver, and can effectively prevent and treat diseases related to the imbalance of in-vivo estrogen level or reduce the symptom.

The invention is related with the chemical synthesis for increase the growth rate in marketable fish and crustacean The aim of this invention is supply GHRP-6 to induce directly or indirectly the release of growthing hormone or like, to produce the increase of circulating growthing hormone level in the blood of the fishes. The peptide is stable, soluble and biologically active. The peptide is able to stimulate growth, improve the larvae quality, and increase the defense against pathogen agents, the dry weight, the protein concentration and the RNA in muscle of fish and crustaceans.

An animal pregnancy test which includes detecting a hormone level in a bodily extract. The bodily extract is tested for a threshold level of the hormone, specifically oestrogen. The test includes a test substance and a material capable of facilitating movement of bodily extract within it. The test substance includes a substance capable of reacting with oestrone sulphate and an indicator dye which is attached to the surface of the substance capable of reacting with oestrone sulphate. The threshold level of the test substance is calibrated to suit specific species and to indicate the desired litter size of that species so that if the detected level of oesterone sulphate exceeds a predetermined threshold level for that species, then there is a high probability of the actual litter size exceeding the calibrated litter size. The apparatus for detecting pregnancy in animals consists of a testing substance, a control test, a sample extractor, and a sample container. The control test consists of a control testing substance which can be either another murine monoclonal antibody or a reagent to any general blood constituent, and an indicator dye.

The invention provides a Chinese medicinal composition containing Chinese yams. The composition consists of the following components in mass ratio: 5 to 25 parts of Chinese yams, 5 to 25 parts of coix seeds and 1 to 15 parts of tangerine peel. The Chinese medicinal composition containing Chinese yams has the main advantages of: (1) reasonable formulation, function of invigorating spleen and regulating qi and capability of effectively regulating astrointestinal motor function; (2) capability of improving stress ability of organisms; (3) capability of regulating hormone level and immune function of stomachs-intestines with functional dyspepsia; and (4) capability of improving the ability of the organisms to clear oxygen free radicals.

The invention relates to a beverage for maintaining beauty and keeping young. The beverage is prepared from the following raw materials: wolfberry, chrysanthemum, semen cuscutae, bright raspberry, rhizoma cimicifugae, fresh purslane and anthocyanin. The preparation method comprises the following steps: juicing the bright raspberry and the fresh purslane; extracting the wolfberry, chrysanthemum, semen cuscutae, and rhizoma cimicifugae; finally, adding the anthocyanin. The beverage disclosed by the invention has the effects of adjusting the function of a human body, regulating the estrogen level and resisting oxidation, and has good effects of relieving climacteric syndrome, treating chloasma, delaying skin aging, improving the smoothness of the skin, resisting creases and facilitating hair growth.

The present invention relates to a control technical system for important metabolic disease of dairy cattle after delivery, belonging to the technical field of veterinary medicine. The technical system is used for controlling and preventing important metabolic diseases of dairy cattle after delivery by detecting dairy cattle before and after delivery in the aspects of dietary cation anion balance (DCAB), oxidation resistance capability of cow plasma (glutathione peroxidase GSH-Px, superoxide dismutase SOD, methylene dioxyamphetamine MDA), plasma leptin hormone levels, liver function indexes (ornithine carbamoyl transferase OCT, aspartate transaminease AST, gamma-glutamyl transpeptidase GGT, total bilirubin Tbil, total protein TP, albumin ALB), blood biochemical indexes (acetone bodies, nonesterified fatty acid NEFA, lactic acid, blood sugar, blood fat, triglyceride TG, total cholesterol TC, calcium, phosphorus and magnesium), cow appetite, milk output increase speed, etc. The important metabolic diseases include cow parturient paresis, retention of afterbirth, endometritis, ketosis, ruminant acidosis, mastitis and fatty liver. The present invention is suitable for preventing and controlling metabolic diseases of dairy cattle after delivery in large-scale dairy farms.

This invention relates to a Chinese medicine compound preparation for treating abortion resulted from abnormal of immune regulation function and deficiency of incretion function which comprises codonopsis pilosula, Cuscuta chinensis, Loranthus parasiticus (L.)Merr and Cortex Eucommiae etc.. Said medicine can regulate the foetus protection immune function and raising increment hormone level to actthe foctus protection effect and is benefical to the foetus growth.

The invention aims at providing a new application of akebiasaponin D, particularly an application of akebiasaponin D in preparing medicines and / or health products for treating and preventing fatty liver and related diseases by using akebiasaponin D as an active component, wherein, the fatty liver comprises alcoholic fatty liver and non-alcoholic fatty liver, and fatty liver and hyperlipidemia due to decreased estrogen levels, and the related diseases comprise fatty liver with lipid metabolism abnormality, hormone level disorder, fatty liver with dyslipidemia, steatohepatitis, liver cirrhosis, and the like. Studies of pharmacology, pharmaceutical effect and toxicology prove that the medicines and / or health products prepared by using akebiasaponin D as the active component have remarkable effects on treating and preventing fatty liver and fatty liver with hyperlipidemia, diabete and other related diseases, and have tiny toxicity.

The invention provides a method and a kit for simultaneously detecting multiple steroid hormones in a blood sample. According to the method, a biological sample is pretreated through methanol deproteinization combination of sodium bicarbonate and a solid-phase support extraction method, chromatographic separation and mass spectrometric detection are performed, a pair of qualitative ions and a pairof quantitative ions are selected for each hormone, and the relative retention time and the qualitative ion pair are used as qualitative basis to determine the content of the sodium bicarbonate in the biological sample. And making a standard curve for quantification by using a standard substance. Meanwhile, three levels of quality control products are applied to investigate the accuracy and effectiveness of the method, and detection result distortion is avoided. The purpose of simultaneously detecting eighteen hormones in a serum sample by applying an HPLC-MS / MS technology is achieved for thefirst time, the influence of interferents is reduced, the method is easy, convenient and rapid to operate, high in flux and low in cost, the steroid hormone level in a human body is effectively monitored in real time, a sufficient basis is provided for clinical disease diagnosis, and the method is worthy of popularization and application.

The present invention relates to non-human transgenic animals, tissues and / or cells derived therefrom having depleted or ablated cytochrome P450 reductase (CPR) expression, methods of producing such animals, tissues and / or cells, and methods of using such animals, tissues and / or cells. Non-human transgenic animals, tissues and or cells derived therefrom of the present invention may be used for, but non exclusively, in both in vivo and in vitro screening of therapeutic agents, drug development, drug metabolism / disposition studies and studying disease states, pregnancy, fetal development, modulation of hormone function and hormone levels, and other pathways and / or substrate metabolism in which cytochrome P450 plays a role.