Immune cells movement speed detection method and system thereof

A technology of immune cells and movement speed, which is applied in the field of biological and microbial analysis and detection, which can solve the problems that the movement speed of immune cells cannot be quantitatively measured, and achieve the effects of short measurement time, convenient operation and high measurement accuracy

Pending Publication Date: 2018-10-23
青岛汉朗智能科技有限公司
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Problems solved by technology

[0006] The purpose of the present invention is to provide a method and system for detecting the movement speed of immune cells to solve the technical problem that the movement speed of immune cells cannot be quantitatively measured in the prior art

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  • Immune cells movement speed detection method and system thereof
  • Immune cells movement speed detection method and system thereof
  • Immune cells movement speed detection method and system thereof

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Embodiment Construction

[0035] The technical solutions of the present invention will be clearly and completely described below in conjunction with the accompanying drawings. Apparently, the described embodiments are some of the embodiments of the present invention, but not all of them. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the protection scope of the present invention.

[0036] In the description of the present invention, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer" etc. The indicated orientation or positional relationship is based on the orientation or positional relationship shown in the drawings, and is only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the referred device or element must have a specific orientation, ...

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Abstract

The invention provides an immune cells movement speed detection method and a system thereof, which relate to the fields of biological and microbiological analysis detection. The method comprises the following steps: discontinuously obtaining several microscopic images containing immune cells; performing edge detection, filling up an internal gas of the edge to form a complete immune cells shape; calculating a change area of the immune cells at different time segments through a XOR operation, according to the change area and a perimeter of a change part, calculating an equivalent length; calculating an equivalent width according to the equivalent length and the change area; and calculating the immune cells movement deformation speed according to the equivalent width and time interval. Compared with the prior art, the immune cells movement speed detection method can be used for directly measuring the motion deformation speed of the immune cells, has the advantages of short measurement time, convenient operation, and no dyeing requirement, more importantly, the method has high measurement precision, is capable of performing quantitative analysis on the movement speed of the immune cells, and determines the activity of the immune cells.

Description

technical field [0001] The invention relates to the field of biological and microbial analysis and detection, in particular to a method and system for detecting the movement speed of immune cells. Background technique [0002] At present, there are few ways to detect the viability of immune cells in clinical practice. T cell proliferation and enzyme-linked immunospot method are mainly used to detect the number of active immune cells and the ability to kill viruses in patients, so as to judge the strength of the patient's autoimmune function, which belongs to indirect detection. method, the detection accuracy is low. [0003] The direct detection method for the detection of immune cell viability is to use the Brinell microscope detection method, and only a drop of blood from a fingertip can be used for manual detection. The Brinell microscope can also analyze and evaluate each person's physical status, hidden dangers and future trends, and provide the most direct, clear, tim...

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N15/10
CPCG01N15/10G01N2015/1006G01N2015/1075
Inventor 刘子萌刘复啟刘有斌
Owner 青岛汉朗智能科技有限公司
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