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Chronic renal failure treatment traditional Chinese medicine preparation and preparation method thereof

A technology of renal function and traditional Chinese medicine, which is applied in the field of traditional Chinese medicine composition for the treatment of chronic renal failure and its preparation field, and achieves the effects of improving renal function, reducing deposition, increasing glomerular filtration rate and renal blood flow

Active Publication Date: 2018-12-25
济南市第四人民医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Chronic renal failure (CRF) is the result of chronic renal parenchymal damage and progressive deterioration caused by various etiologies. syndrome, there is currently no effective way to reverse the course of the disease, and dialysis is the last option for life-sustaining patients with chronic renal failure

Method used

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  • Chronic renal failure treatment traditional Chinese medicine preparation and preparation method thereof
  • Chronic renal failure treatment traditional Chinese medicine preparation and preparation method thereof
  • Chronic renal failure treatment traditional Chinese medicine preparation and preparation method thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0031] Example 1, Astragalus 12 liang, Salvia miltiorrhiza 14.5 liang, Codonopsis 9 liang, Rhubarb 8.8 liang, Yimu 10 liang, Poria cocos 8 liang, Atractylodes macrocephala 8.5 liang, Epimedium 7 liang, Shouwu 8 liang, and Coptis 4 liang. The medicinal materials are cleaned to remove impurities (all are identified as pharmacopoeia varieties and meet the pharmacopoeia standards), and 1 / 3 of rhubarb is crushed into fine powder for later use. Mix the remaining astragalus and other raw materials into the extraction container, add 10 times the amount of water to decoct and extract twice, each time for 1.5 hours, combine the two extracts, and high-speed centrifuge filter (rotating speed 16000 rpm, the temperature of the drug solution is not lower than 60°C), the filtrate was concentrated under reduced pressure to a clear paste with a relative density of about 1.20, added rhubarb powder and stirred evenly, dried below 80°C, crushed into fine powder, granulated with 80% ethanol as a wet...

Embodiment 2

[0032] Example 2: Astragalus 10 liang, Danshen 15 liang, Codonopsis 7 liang, Rhubarb 12 liang, Yimu 8 liang, Poria 9 liang, Atractylodes macrocephala 6.5 liang, Epimedium 7.8 liang, Shouwu 8 liang, and Coptis 6 liang. The medicinal materials are cleaned to remove impurities (all are identified as pharmacopoeia varieties and meet the pharmacopoeia standards), and 1 / 3 of rhubarb is crushed into fine powder for later use. Mix the remaining astragalus and other raw materials into the extraction container, add 10 times the amount of water to decoct and extract twice, each time for 1.5 hours, combine the two extracts, and high-speed centrifuge filter (rotating speed 16000 rpm, the temperature of the drug solution is not lower than 60°C), the filtrate was concentrated under reduced pressure to a clear paste with a relative density of about 1.20, added rhubarb powder and stirred evenly, dried below 80°C, crushed into fine powder, granulated with 80% ethanol as a wetting agent, dried, a...

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Abstract

The invention belongs to the technical field of traditional Chinese medicine formulas, and relates to a chronic renal failure treatment traditional Chinese medicine composition and a preparation method thereof. The traditional Chinese medicine composition is prepared from 10-15 parts of Radix astragali, 10-15 parts of radix salviae milti orrhizae, 7-12 parts of radix codonopsis, 7-12 parts of radix et rhizoma rhei, 7-12 parts of herba leonuri, 6-10 parts of poria, 6-10 parts of rhizoma atractylodis macrocephalae, 5-8 parts of herba epimedii, 5-8 parts of radix polygoni multiflori and 3-6 partsof rhizoma coptidis. The traditional Chinese medicine composition has effects of effectively reducing blood triglyceride, cholesterol and low-density lipoprotein of patients and improving various serum lipid parameters in different degrees, increasing anemia patient's hemoglobin (Hb) content and improving the patient's anaemic status, improving various hemorheological indexes and improving hypercoagulability and blood circulation, has comprehensive functions of tonifying kidney, spleen and qi, removing turbid materials, clearing damp and dispersing blood stasis, and is an effective composition for treating chronic renal failure.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine formulas, and relates to a traditional Chinese medicine composition for treating chronic renal failure and a preparation method thereof. Background technique [0002] Chronic renal failure (CRF) is the result of chronic renal parenchymal damage and progressive deterioration caused by various etiologies. Syndrome, currently there is no effective way to reverse the course of the disease, and dialysis is the last option for patients with chronic renal failure to maintain life. Effective drug treatment can alleviate the clinical symptoms of CRF patients, improve and protect the residual renal function of patients, delay the progression of CRF, delay the time of dialysis or prolong the interval of dialysis, and improve the quality of life of patients, which is the main purpose of clinical drug treatment of CRF. Therefore, the development and production of effective therapeutic dru...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/718A61K9/16A61P13/12
CPCA61K9/1617A61K36/076A61K36/284A61K36/296A61K36/344A61K36/481A61K36/533A61K36/537A61K36/704A61K36/708A61K36/718A61P13/12A61K2300/00
Inventor 刘金凤李娟任秀明
Owner 济南市第四人民医院
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