13 results about "Blood triglycerides" patented technology

The invention provides a method for preparing quintuple diglyceride oil for improving blood vessel health through enzymolysis, application and a product, and belongs to the technical field of enzyme engineering. The preparation method comprises the following steps: mixing low-erucic acid rapeseed oil, glycerol, water, fatty acid and lipase, and carrying out enzymolysis reaction, molecular distillation, decoloration and deodorization to obtain diglyceride oil; the lipase is a mixture of Candida antarctica Aspergillus niger lipase, Candida column lipase and bovine pancreas lipase, and the weight ratio of the low-erucic acid rapeseed oil to the glycerin to the water to the fatty acid to the lipase is 500: (80-100): (1-2): (30-60): (10-20). The diglyceride oil prepared by the method can be used for preparing a diglyceride oil composition, and has five functions of reducing blood uric acid, reducing blood total cholesterol, reducing blood triglyceride, reducing blood sugar and increasing blood flow velocity to improve blood vessel health.

The present invention belongs to the field of biomedical technology and provides an application of betulinone and its analogs in the prevention and treatment of fatty liver disease and adjuvant lipid-lowering. The present invention also provides a composition for treating fatty liver disease or adjuvant lipid-lowering, which comprises an effective dose of betulinone and its analogs. The betulinone and its analogs provided by the present invention have the effects of reducing blood triglyceride and liver triglyceride in vivo, reversing liver steatosis, and can improve liver fibrosis and inflammatory symptoms of mice with fatty hepatitis, and have good safety and no toxic side effects, and can be used for preparing preventive and therapeutic drugs for fatty liver disease, fatty hepatitis and related diseases.

The application provides a method, application and product for preparing a triglyceride oil with five effects of improving blood vessel health by enzymolysis, and belongs to the technical field of enzyme engineering. The preparation method comprises the following steps: mixing low erucic acid rapeseed oil, glycerol, water, fatty acid and lipase, performing enzymolysis reaction, performing molecular distillation, and performing decolorization and deodorization to obtain the triglyceride oil; the lipase is a mixture of Candida antarctica black Aspergillus niger lipase, Candida cylindracea lipase and bovine pancreas lipase; and the weight ratio of the low erucic acid rapeseed oil, glycerol, water, fatty acid and lipase is 500:80-100:1-2:30-60:10-20. The triglyceride oil prepared by the method can be used to prepare a triglyceride oil composition, and has the five effects of lowering blood uric acid, lowering blood total cholesterol, lowering blood triglyceride, lowering blood sugar and improving blood flow speed, thereby improving blood vessel health.

The present invention relates to a composition comprising a Salvia miltiorrhiza or Paeonia lactiflora extract as an active ingredient for prevention or treatment of lipid metabolism disorder and, more particularly, provides a pharmaceutical composition and a health functional food composition, each comprising a Salvia miltiorrhiza extract, a Paeonia lactiflora extract, or an extract from a mixture of Salvia miltiorrhiza and Paeonia lactiflora as an active ingredient for prevention or treatment of lipid metabolism disorder. The composition prevents the differentiation of preadipocyte cells to adipocyte cells, reduces blood triglyceride and cholesterol levels, and effectively suppresses fatty liver and visceral fat formation and as such, can be advantageously used as a pharmaceutical and food composition for prevention, alleviation, or treatment of lipid metabolism disorder.

The application belongs to the technical field of medicine, and discloses a kind of optical compound and its preparation method and application, specifically discloses the enantiomer has different effect.In vitro experiment, enantiomer shows selectivity to target point, S-isomer tends to activate PPARγ, and R-isomer tends to activate FFAR1.In animal model, the efficacy of enantiomer also shows difference, first, two enantiomers can significantly reduce the blood sugar of animal, and significantly improve the insulin resistance of animal.However, in reducing blood triglyceride, the effect of S-isomer is obviously superior to racemate and R-isomer, and in reducing blood cholesterol, the effect of R-isomer is obviously superior to racemate and S-isomer.Therefore, (S)‑1 has important role in preparing blood sugar reducing, triglyceride reducing drug, and (R)‑1 has more significant effect in reducing blood sugar, reducing cholesterol, and has important significance for clinical targeted treatment and application.

The present invention relates to a composition for regulating hepatic lipid metabolism, comprising Lactiplantibacillus plantarum OPT-A1 strain deposited under accession number KCTC 15555BP, a culture liquid thereof, a cultured product thereof, or a culture lysate thereof. The composition suppresses lipid accumulation and expression of genes related to lipogenesis in hepatocytes, and enhances expression of genes related to lipid oxidation. In addition, the composition inhibits accumulation of triglycerides in hepatocytes and reduces blood triglyceride levels, total cholesterol levels, and liver injury indices. Furthermore, the composition promotes rapid consumption of lipids in hepatocytes and somatic cells through enhancement of muscle mass, and thus can be advantageously used as a raw material for foods, pharmaceuticals, and the like related to alleviation and treatment of various metabolic diseases.

To provide an oral composition that can be used for anti-obesity, body fat reduction, abdominal fat or visceral fat reduction, BMI reduction, reduction or elevation suppression of blood triglycerides, reduction of blood cholesterol, promotion of lipolysis, promotion of fat burning, improvement of energy consumption, suppression of fat accumulation, and suppression of adipocyte maturation. 【Solution means】An oral composition containing gallocatechinol and hydroxycitric acid, wherein the mass ratio of gallocatechinol to hydroxycitric acid in the composition is gallocatechinol:hydroxycitric acid = 1:0.01 to 10. The oral composition preferably further contains isogallocatechinol.

The present application belongs to the field of analytical chemistry and electrochemistry, and particularly relates to an electrochemical sensor, a preparation method and application thereof in detection of sweat triglyceride content. A wearable sensor is prepared based on C-ZIF-67 / KB nanocomposite material, the sensor realizes detection of sweat triglyceride for the first time, and it is verified that sweat triglyceride level has high correlation with blood triglyceride level (correlation coefficient is 0.813, n=35). Through verification of a commercial colorimetric analysis kit, the sensor obtains a high correlation coefficient of 0.853 in detection of sweat triglyceride, which shows excellent accuracy.

A method of treating body composition resistance in a mammal is provided comprising administering to the mammal for a sufficient period of time nutrients comprising protein in an amount of 10-100g, creatine in an amount of 1-5g, vitamin D in an amount of 50-4000 IU, calcium in an amount of 100-1000 mg, and omega-3 fatty acids in an amount of 500-15,000 mg. In embodiments, the method additionally improves one or more of lean mass, muscle strength, body composition index, fat mass and % body fat, systemic inflammation levels, blood cholesterol levels and / or blood triglyceride levels

A gene editing system comprising: (a) a gene editor fusion protein comprising a Cas protein and a deaminase, or a nucleic acid encoding the gene editor fusion protein, and (b) a hybrid guide nucleic acid comprising a spacer sequence, wherein the spacer sequence comprises at least one deoxyribonucleotide and a plurality of ribonucleotide is claimed. A 2’ hydroxyl group of a ribose on at least one ribonucleotide may be covalently linked to a methyl group (2’-OMe). The gene editing system for use in treating or preventing an atherosclerotic cardiovascular disease, or lowering blood low-density lipoprotein cholesterol (LDL-C) levels or lowering blood triglyceride levels is further claimed. [None]

To provide an adjusted meal for improving health conditions.SOLUTION: A dietary regimen for improving health conditions, wherein an adjusted diet is continually consumed for at least one meal selected from breakfast, lunch, and dinner, and wherein the health conditions are assessed by one or more health indicators selected from body weight, BMI, body fat percentage, blood pressure, blood triglycerides, bone density, presenteeism, oxidative stress marker, stool frequency, and intestinal flora diversity.SELECTED DRAWING: Figure 2

The application provides biomass fiber aerogel and a preparation method and application thereof, and specifically, the aerogel comprises nanoparticles and biomass fibers, the nanoparticles are arranged on surfaces of the biomass fibers; the nanoparticles comprise shellac; and the biomass fibers comprise chitin.The aerogel has micro-plastic removal and lipid metabolism regulation functions, can be adapted to oil-water mixed systems of different oil types and different oil concentrations, can maintain structural stability and high adsorption performance in a complex static / dynamic digestion environment, and can reduce fat accumulation in the body, reduce blood triglyceride content, promote excretion of lipid feces and regulate lipid metabolism.In addition, the aerogel has good biocompatibility, is biodegradable, has no risk of in-vivo accumulation and has good clinical safety.

The invention provides bacillus natto and application, and belongs to the technical field of microorganisms. The bacillus natto disclosed by the invention is bacillus natto DG2-7 which is preserved in the China General Microbiological Culture Collection Center (CGMCC) and has the preservation number of CGMCC No.36482, and relates to application of the bacillus natto DG2-7 in improvement of intestinal functions and body metabolism. The strain can be used for preparing natto, natto powder, natto tablets and other preparations, has the effects of regulating constipation, diarrhea, flatulence, sour regurgitation and bad breath, can assist in reducing blood triglyceride and relieving gout, and is beneficial to relieving female dysmenorrhea. In a test, good intestinal regulation and metabolism improvement effects are shown, and the comprehensive function is superior to that of a commercially available probiotic product.