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8 results about "Blood triglycerides" patented technology

Method for the preparation of a penta-upgraded blood vessel health improving diglyceride oil by enzymatic hydrolysis, uses and products

The application provides a method, application and product for preparing a triglyceride oil with five effects of improving blood vessel health by enzymolysis, and belongs to the technical field of enzyme engineering. The preparation method comprises the following steps: mixing low erucic acid rapeseed oil, glycerol, water, fatty acid and lipase, performing enzymolysis reaction, performing molecular distillation, and performing decolorization and deodorization to obtain the triglyceride oil; the lipase is a mixture of Candida antarctica black Aspergillus niger lipase, Candida cylindracea lipase and bovine pancreas lipase; and the weight ratio of the low erucic acid rapeseed oil, glycerol, water, fatty acid and lipase is 500:80-100:1-2:30-60:10-20. The triglyceride oil prepared by the method can be used to prepare a triglyceride oil composition, and has the five effects of lowering blood uric acid, lowering blood total cholesterol, lowering blood triglyceride, lowering blood sugar and improving blood flow speed, thereby improving blood vessel health.
Owner:广东善百年特医食品有限公司

Optically active compounds, processes for their preparation and use thereof

PendingCN122627980AObvious effectReduce random blood sugarLow glucoseEnantiomer
The application belongs to the technical field of medicine, and discloses a kind of optical compound and its preparation method and application, specifically discloses the enantiomer has different effect.In vitro experiment, enantiomer shows selectivity to target point, S-isomer tends to activate PPARγ, and R-isomer tends to activate FFAR1.In animal model, the efficacy of enantiomer also shows difference, first, two enantiomers can significantly reduce the blood sugar of animal, and significantly improve the insulin resistance of animal.However, in reducing blood triglyceride, the effect of S-isomer is obviously superior to racemate and R-isomer, and in reducing blood cholesterol, the effect of R-isomer is obviously superior to racemate and S-isomer.Therefore, (S)‑1 has important role in preparing blood sugar reducing, triglyceride reducing drug, and (R)‑1 has more significant effect in reducing blood sugar, reducing cholesterol, and has important significance for clinical targeted treatment and application.
Owner:INST OF MATERIA MEDICA CHINESE ACAD OF MEDICAL SCI

Composition for regulating hepatic lipid metabolism, comprising lactiplantibacillus plantarum opt-a1 strain

PCT designated stageWO2026095764A1Digestive systemUnknown materialsLiver necrosisSomatic cell
The present invention relates to a composition for regulating hepatic lipid metabolism, comprising Lactiplantibacillus plantarum OPT-A1 strain deposited under accession number KCTC 15555BP, a culture liquid thereof, a cultured product thereof, or a culture lysate thereof. The composition suppresses lipid accumulation and expression of genes related to lipogenesis in hepatocytes, and enhances expression of genes related to lipid oxidation. In addition, the composition inhibits accumulation of triglycerides in hepatocytes and reduces blood triglyceride levels, total cholesterol levels, and liver injury indices. Furthermore, the composition promotes rapid consumption of lipids in hepatocytes and somatic cells through enhancement of muscle mass, and thus can be advantageously used as a raw material for foods, pharmaceuticals, and the like related to alleviation and treatment of various metabolic diseases.
Owner:OPTBIO INC

An electrochemical sensor, a preparation method and application thereof in detecting sweat triglyceride content

The present application belongs to the field of analytical chemistry and electrochemistry, and particularly relates to an electrochemical sensor, a preparation method and application thereof in detection of sweat triglyceride content. A wearable sensor is prepared based on C-ZIF-67 / KB nanocomposite material, the sensor realizes detection of sweat triglyceride for the first time, and it is verified that sweat triglyceride level has high correlation with blood triglyceride level (correlation coefficient is 0.813, n=35). Through verification of a commercial colorimetric analysis kit, the sensor obtains a high correlation coefficient of 0.853 in detection of sweat triglyceride, which shows excellent accuracy.
Owner:CHINA AGRI UNIV

Gene editing of PCSK9 or ANGPTL3 and compositions and methods of using same for treatment of disease

A gene editing system comprising: (a) a gene editor fusion protein comprising a Cas protein and a deaminase, or a nucleic acid encoding the gene editor fusion protein, and (b) a hybrid guide nucleic acid comprising a spacer sequence, wherein the spacer sequence comprises at least one deoxyribonucleotide and a plurality of ribonucleotide is claimed. A 2’ hydroxyl group of a ribose on at least one ribonucleotide may be covalently linked to a methyl group (2’-OMe). The gene editing system for use in treating or preventing an atherosclerotic cardiovascular disease, or lowering blood low-density lipoprotein cholesterol (LDL-C) levels or lowering blood triglyceride levels is further claimed. [None]
Owner:VERVE THERAPEUTICS INC

Adjusted meal

To provide an adjusted meal for improving health conditions.SOLUTION: A dietary regimen for improving health conditions, wherein an adjusted diet is continually consumed for at least one meal selected from breakfast, lunch, and dinner, and wherein the health conditions are assessed by one or more health indicators selected from body weight, BMI, body fat percentage, blood pressure, blood triglycerides, bone density, presenteeism, oxidative stress marker, stool frequency, and intestinal flora diversity.SELECTED DRAWING: Figure 2
Owner:NISSIN FOODS HOLDINGS CO LTD

Biomass fiber aerogel and preparation method and application thereof

ActiveCN121987808BBiotechnologyFiber
The application provides biomass fiber aerogel and a preparation method and application thereof, and specifically, the aerogel comprises nanoparticles and biomass fibers, the nanoparticles are arranged on surfaces of the biomass fibers; the nanoparticles comprise shellac; and the biomass fibers comprise chitin.The aerogel has micro-plastic removal and lipid metabolism regulation functions, can be adapted to oil-water mixed systems of different oil types and different oil concentrations, can maintain structural stability and high adsorption performance in a complex static / dynamic digestion environment, and can reduce fat accumulation in the body, reduce blood triglyceride content, promote excretion of lipid feces and regulate lipid metabolism.In addition, the aerogel has good biocompatibility, is biodegradable, has no risk of in-vivo accumulation and has good clinical safety.
Owner:WUHAN UNIV

Bacillus natto and application thereof

PendingCN121852290ABacteriaMetabolism disorderBiotechnologyAntiflatulent
The invention provides bacillus natto and application, and belongs to the technical field of microorganisms. The bacillus natto disclosed by the invention is bacillus natto DG2-7 which is preserved in the China General Microbiological Culture Collection Center (CGMCC) and has the preservation number of CGMCC No.36482, and relates to application of the bacillus natto DG2-7 in improvement of intestinal functions and body metabolism. The strain can be used for preparing natto, natto powder, natto tablets and other preparations, has the effects of regulating constipation, diarrhea, flatulence, sour regurgitation and bad breath, can assist in reducing blood triglyceride and relieving gout, and is beneficial to relieving female dysmenorrhea. In a test, good intestinal regulation and metabolism improvement effects are shown, and the comprehensive function is superior to that of a commercially available probiotic product.
Owner:HUAIAN ANDIYUAN BIOTECHNOLOGY CO LTD